Results 261 to 270 of about 3,430,031 (362)

The Effect of Hyperoxia on Nitric Oxide Metabolism in the Skeletal Muscle of Male Type 2 Diabetic Rats. [PDF]

Endocrinol Diabetes Metab
Mousavi M, Jeddi S, Norouzirad R, Ghasemi A.   +3 more
europepmc   +1 more source

Advanced Biomaterial Delivery of Hypoxia‐Conditioned Extracellular Vesicles (EVs) as a Therapeutic Platform for Traumatic Brain Injury

Advanced Science, EarlyView.
This research introduces a novel approach to enhance neuroregeneration following Traumatic Brain Injury (TBI). Extracellular Vesicles (EVs) are isolated from human neural progenitor cells under hypoxic conditions, leading to enhanced expression of neurogenic and angiogenic factors.
Joshua B. Stein, Songzi Zhang, Eun Ji Roh, Jeffrey Luo, Meizi Chen, Hyunjun Jang, Li Ling Goldston, Brandon Conklin, Inbo Han, Ki‐Bum Lee   +9 more
wiley   +1 more source

Regenerating aged bone marrow via a nitric oxide nanopump. [PDF]

Nat Commun
Li K, Hu S, Li H, Lin W, Zhao D, Xu Z, Pan C, Wang H, Li D, Liu J, Chen H.   +10 more
europepmc   +1 more source

Aberrant Mitochondrial Metabolism in Alzheimer's Disease Links Energy Stress with Ferroptosis

Advanced Science, EarlyView.
Alves et al. reveal how energy loss and oxidative stress, two major features of Alzheimer's disease, are connected. Mitochondria controls the flux of the antioxidant glutathione (GSH), via facilitating both its production and consumption. Energy restriction limits GSH synthesis, conferring vulnerability to cell death by ferroptosis, implicated as a ...
Francesca Alves, Darius Lane, Adam Wahida, Md. Jakaria, Pawel Kalinowski, Adam Southon, Abdel Ali Belaidi, Teresa Samperi‐Esteve, Triet Phu Minh Nguyen, Peng Lei, Marcus Krueger, Stefan Mueller, Marcus Conrad, Puja Agarwal, Sue E Leurgans, Julie Schneider, Ashley I. Bush, Scott Ayton   +17 more
wiley   +1 more source

Noninvasive Disease Assessment in Eosinophilic Esophagitis With Fractionated Exhaled Nitric Oxide, Blood, and Fecal Biomarkers. [PDF]

J Clin Gastroenterol
Göldi A, Kaymak T, Esposito L, Lehmann A, Negoias S, Tamm M, Niess JH, Hruz P.   +7 more
europepmc   +1 more source

Optimized Monothiol Thioredoxin Derivative (ORP100S) Protects In Vitro and In Vivo from Radiation and Chemotoxicity Without Promoting Tumor Proliferation

Advanced Science, EarlyView.
Native thioredoxin‐1 (TRX) stimulates proliferation and rescues stem cells and cancer cells from multiple stressors by suppressing p53 and inhibiting ferroptosis via GPX4/SLC7A11 upregulation mediated by enhanced KLF4 expression and p53 promoter binding.
Jian Wu, Xiaobei Wang, Parker Mathews, Shaima Jabbar, Min Zhang, Haim Moskowitz, Wei Duan, David P. Nichols, George William Schaaf, John D. Olson, Andrew N. Macintyre, J. Daniel Bourland, Ivan Spasojevic, Jen‐Tsan Ashley Chi, Joel Ross, Nelson Chao, J. Mark Cline, Peter B. Heifetz, Yubin Kang   +18 more
wiley   +1 more source

Medical gases in respiratory diseases: ozone, argon, and nitric oxide as game-changers in therapeutics. [PDF]

Front Med (Lausanne)
Chen L, Cai Q, Zheng P.
europepmc   +1 more source

Arginine Metabolic Disruption Impairs Hair Regeneration via ROS‐Mediated Inactivation of mTOR Signaling in Androgenetic Alopecia

Advanced Science, EarlyView.
Arginine deficiency accelerates androgenetic alopecia. Serum metabolome shows reduced circulating arginine, while local metabolic disruption depletes follicular reserves, triggering reactive oxygen species (ROS) accumulation and mTOR suppression that induce hair miniaturization.
Shixin Duan, Guo Li, Yanji Chu, Junbo Zhang, Li Yang, Yujin Zhang, Fangfen Liu, Jiayun Li, Mengting Chen, Ben Wang, Zhixiang Zhao, Wei Shi, Yiya Zhang, Guangtong Deng, Xinwei Kuang, Hongfu Xie, Yufan Cheng, Zhili Deng, Ji Li, Yan Tang   +19 more
wiley   +1 more source

Production and Role of Nitric Oxide in Endometrial Cancer. [PDF]

Antioxidants (Basel)
Yeo SG, Oh YJ, Lee JM, Yeo JH, Kim SS, Park DC.   +5 more
europepmc   +1 more source

Robust and Reversible Supramolecular Adhesive via Dynamic Covalent Bond Crosslinking‐Induced Assembly of Metal‐Coordinated Nanoparticles

Advanced Science, EarlyView.
A supramolecular polymer network is constructed through the assembly of metal‐coordinated nanoparticles induced by the crosslinking of dynamic covalent disulfide bond. The resulting supramolecular adhesive exhibited excellent adhesion performance, including strong adhesion strength, exceptional solvent resistance, and distinct reversible adhesion ...
Yanyan Guo, Mengran Zhang, Shuanggen Wu, Xunqiu Wang   +3 more
wiley   +1 more source