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In plants, NADPH oxidase (NOX) is also known as a respiratory burst oxidase homolog (Rboh). This highly important enzyme, one of the main enzymatic sources of superoxide radicals (O2•−), is involved in the metabolism of reactive oxygen and ...
Ángela Chu-Puga+4 more
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Cancer is considered one of the main causes of human death worldwide, being characterized by an alteration of the oxidative metabolism. Many natural compounds from plant origin with anti-tumor attributes have been described.
Marta Rodríguez-Ruiz+8 more
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In contrast to nitric oxide, which has well established and important roles in the regulation of blood flow and thrombosis, neurotransmission, the normal functioning of the genitourinary system, and the inflammation response and host defense, its ...
V. Kapil+7 more
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Nitric oxide and glomerulonephritis [PDF]
The glomerulus is a unique vascular network with the potential to express several isoforms of nitric oxide synthase (NOS). Induction of inducible NOS (iNOS) occurs as part of a rapid initial response to immune injury in glomerulonephritis (GN). Studies on rodent models suggest that this is due to activation of transcription factors by reactive oxygen ...
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Biotransformation of Nitric Oxide [PDF]
Previous investigations into the health effects of nitrogen oxides (NOx) have mostly been conducted with special reference to nitrogen dioxide (NO2) and its direct effects on the respiratory system, while the study of nitric oxide (NO) has been disregarded.
Katsumi Yoshida, Kazuo Kasama
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Background: Intrinsic factor (IF) is a glycoprotein crucial for cobalamin (vitamin B12) absorption in the human body. This study aimed to evaluate the binding affinity of nitrosylcobalamin (NO-Cbl), a cobalamin analog, to recombinant ...
Annette M. Sysel, Joseph A. Bauer
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Low temperature (LT) negatively affects plant growth and development via the alteration of the metabolism of reactive oxygen and nitrogen species (ROS and RNS).
Juan C. Begara-Morales+8 more
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Environmental stresses negatively affect plant growth, development and crop productivity [...]
Mounira Chaki+2 more
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Nitric oxide and reproduction [PDF]
639 tion. Moreover, local synthesis of NO within the uterus may be important for regulating myometrial activity, i.e. spontaneous contraction and relaxation of the uterus. Buhimschi et al. (1996) demonstrated that the rat cervix expressed all three isoforms of NOS (iNOS, nNOS, eNOS), whereas the uterus expressed only iNOS and eNOS, but not nNOS ...
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Refractory hypotension with end-organ hypoperfusion and failure is an ominous feature of shock. Distributive shock is caused by severe infections (septic shock) or severe systemic allergic reactions (anaphylactic shock). In 1986, it was concluded that nitric oxide (NO) is the endothelium-derived relaxing factor that had been discovered 6 years earlier.
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