Nitric oxide synthase - Open Access .click

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Novel features of nitric oxide, endothelial nitric oxide synthase, and atherosclerosis

Current Atherosclerosis Reports, 2004
There is a complex pathophysiologic scenario involving nitric oxide (NO), endothelial nitric oxide synthase (eNOS), and the development of atherosclerosis and unstable atheroma. Endothelial damage induced by atherosclerosis leads to the reduction in bioactivity of eNOS with subsequent impaired release of NO.
Claudio Napoli, Louis J. Ignarro
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Modulation of nitric oxide synthase by nitric oxide donor compounds in migraine

International Journal of Clinical & Laboratory Research, 1998
A controlled study was performed to assess the involvement of the nitric oxide pathway in migraine pathophysiology. Thirteen patients with migraine without aura and seven clinically healthy subjects (C) were selected. All of the migraine patients were studied both before, during an asymptomatic phase (t0), and 1 h after the administration of 5 mg ...
MARTELLETTI, Paolo +5 more
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Tetrahydrobiopterin and Nitric Oxide Synthase Recouplers

2020
Generation of nitric oxide (NO) by the nitric oxide synthase (NOS) enzymes plays multiple signalling roles in every organ system, with crucial roles in the cardiovascular system, mediated by endothelial nitric oxide synthase (eNOS, encoded by NOS3) and neuronal nitric oxide synthase (nNOS, encoded by NOS1) in regulation of blood pressure, flow, oxygen ...
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Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation