Results 131 to 140 of about 508,056 (310)

NITRIC OXIDE SYNTHASE AND THE EFFECT OF VITAMIN E ON NITRIC OXIDE SYNTHASE IN CHRONIC DIABETİC RAT PENİS

Urology Research and Practice, 2019
To determine nitric oxide synthase content in chronic diabetic rat penis and the effect of vitamin E on nitric oxide synthase in diabetic rats. 7” Male, young-adult Sprague-Dawley rats weighing 180-250 gr were divided into three groups: diabetic (n ...
B. Alıcı, M.K. Gümüştaş, E. Akkuş, H. Özkara, E. İkitimur, H. Hattat   +5 more
doaj  

Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors.

Circulation, 1998
U. Laufs, V. La Fata, J. Plutzky, James K. Liao   +3 more
semanticscholar   +1 more source

Dual Regulatory Functions of Classical Zinc Finger Clusters from Myeloid Zinc Finger‐1

Chemistry – A European Journal, EarlyView.
The classical zinc finger (ZF) protein MZF1 uses two ZF clusters to achieve metal‐dependent and gene‐specific promoter recognition. The differential redox stability and modular utilization of the two ZF clusters enable MZF1 to regulate cerebrovascular, neuronal, and cancer‐related transcriptional programs.
Yunha Hwang, Yerim Park, Nohwan Park, Heeju Noh, Hyun Goo Kang, Seung Jae Lee   +5 more
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

The Intricate Mechanism of Nitric Oxide Synthase. [PDF]

J Comput Chem
Siegbahn PEM.
europepmc   +1 more source

Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alpha1-syntrophin mediated by PDZ domains.

Cell, 1996
J. Brenman, D. Chao, S. H. Gee, Aaron W. McGee, S. E. Craven, D. Santillano, Zi-Qiang Wu, Fred Huang, Hou-Hui Xia, M. F. Peters, S. Froehner, D. Bredt   +11 more
semanticscholar   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Targeting Temozolomide-Resistant Glioblastoma: Therapeutic Potential of Neuronal Nitric Oxide Synthase Inhibitor. [PDF]

Cancer Med
Nimgampalle M, Ojha SK, Kartawy M, Feivelson M, Amal H.   +4 more
europepmc   +1 more source

Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension.

Journal of Clinical Investigation, 2003
U. Landmesser, S. Dikalov, S. Price, Louise A. McCann, T. Fukai, Steven M. Holland, W. Mitch, D. G. Harrison   +7 more
semanticscholar   +1 more source

Statin use and risk of remote seizure after first new onset status epilepticus

Epilepsia, EarlyView.
Abstract Objective Preclinical evidence supports the role of statins as antiepileptogenic agents. In this study, we investigated the risk of remote unprovoked seizures (RS) according to the use of statin therapy in a cohort of first‐ever status epilepticus (SE) survivors. Methods Retrospective analysis was made of adult patients (age ≥ 14 years) with a
Niccolò Orlandi, Giada Giovannini, Lisa Taruffi, Margherita Burani, Jefe Laureine Ngnintedem Dontsop, Mara Malerba, Simona Scolastico, Laura Madrassi, Leonardo Affronte, Matteo Pugnaghi, Anna Elisabetta Vaudano, Simona Lattanzi, Stefano Meletti   +12 more
wiley   +1 more source