Results 1 to 10 of about 96,804 (115)

Inducible nitric oxide synthase-expressing myeloid-derived suppressor cells regulated by interleukin 35 contribute to the pathogenesis of psoriasis [PDF]

Frontiers in Immunology, 2023
Although psoriasis is classified as a T cell-mediated inflammatory disease, the contribution of myeloid cells to the pathogenesis of psoriasis is not fully understood.
Junfeng Zhang, Junfeng Zhang, Yunsheng Zhang, Zhiya Yang, Dalei Cheng, Hui Zhang, Hui Zhang, Li Wei, Chen Liu, Fenglian Yan, Fenglian Yan, Chunxia Li, Chunxia Li, Guanjun Dong, Guanjun Dong, Changying Wang, Changying Wang, Dongmei Shi, Huabao Xiong   +18 more
doaj   +2 more sources

Inducible nitric oxide synthase deficiency promotes murine-β-coronavirus induced demyelination [PDF]

Virology Journal, 2023
Background Multiple sclerosis (MS) is characterized by neuroinflammation and demyelination orchestrated by activated neuroglial cells, CNS infiltrating leukocytes, and their reciprocal interactions through inflammatory signals.
Mithila Kamble, Fareeha Saadi, Saurav Kumar, Bhaskar Saha, Jayasri Das Sarma   +4 more
doaj   +2 more sources

Zinc-fortification restores gut nitric oxide without expression of inducible nitric oxide synthase gene in enterotoxigenic E. coli-induced diarrhea in zinc-deficient rats

Scientific African, 2021
Nitric oxide maintains the integrity of the gastric epithelium and is also elevated in diarrheal disease condition. Nitric oxide synthase isoforms (NOS) are responsible for production of nitric oxide (NO) in physiological and pathophysiological ...
Ebuka E. David, Muhammad A. Yameen, Ikechuku O. Igwenyi, Chidinma N. David   +3 more
doaj   +1 more source

Nitric oxide in gingival crevicular fluid and nitric oxide synthase expression in the gingiva of patients with sickle cell disease

Turkish Journal of Hematology, 2011
OBJECTIVE: This study aimed to biochemically measure the production of nitric oxide in gingival crevicular fluid and immunohistochemically measure the expression of inducible nitric oxide synthase in the gingiva of patients with sickle cell disease ...
Esra Güzeldemir, Hilal Uslu Toygar, Nebil Bal, Ruksan Anarat, Can Boğa   +4 more
doaj   +3 more sources

Pro- and anti-fibrotic effects of vascular endothelial growth factor in chronic kidney diseases

Renal Failure, 2022
Renal fibrosis is the inevitable common end-point of all progressive chronic kidney diseases. The underlying mechanisms of renal fibrosis are complex, and currently there is no effective therapy against renal fibrosis.
Changxiu Miao, Xiaoyu Zhu, Xuejiao Wei, Mengtuan Long, Lili Jiang, Chenhao Li, Die Jin, Yujun Du   +7 more
doaj   +1 more source

Nitric oxide in liver fibrosis: The role of inducible nitric oxide synthase [PDF]

Clinical and Molecular Hepatology, 2015
The inducible form of nitric oxide synthase (iNOS) is expressed in hepatic cells in pathological conditions. Its induction is involved in the development of liver fibrosis, and thus iNOS could be a therapeutic target for liver fibrosis.
Yasuko Iwakiri
doaj   +1 more source

Effects of Chitosan on the Secretion of Cytokines and Expression of Inducible Nitric Oxide Synthase mRNA in Peritoneal Macrophages of Broiler Chicken

Brazilian Archives of Biology and Technology, 2014
An in vitro experiment was conducted to study the effects of chitosan on the secretion of cytokines and expression of inducible nitric oxide synthase mRNA in peritoneal macrophages of broiler chicken.
Huiying Li, Binlin Shi, Sumei Yan, Tianzhang Zhao, Junliang Li, Xiaoyu Guo   +5 more
doaj   +1 more source

Examination of the different medicine effects at MDAH-2774 human ovary cancer three dimensional cell culture with nitric oxide synthase changing

Cerrahpaşa Medical Journal, 2013
Objectives: The purpose of our study is to examine the effects of the various medicines at the three dimensional MDAH-2774 human ovary cancer culture with cell proliferation and nitric oxide synthase changing.
Şule Ayla, Gülperi Öktem, Ayhan Bilir
doaj   +1 more source

Synthesis of N-(Methoxycarbonylthienylmethyl)thioureas and Evaluation of Their Interaction with Inducible and Neuronal Nitric Oxide Synthase

Molecules, 2010
Two isomeric N-(methoxycarbonylthienylmethyl)thioureas were synthesised by a sequence of radical bromination of methylthiophenecarboxylic esters, substitution with trifluoroacetamide anion, deprotection, formation of the corresponding isothiocyanates and
Michael D. Threadgill, Claire L.M. Goodyer, Ghadeer A.R.Y. Suaifan   +2 more
doaj   +1 more source

Study of the nitric oxide system in the rat cerebellum during aging

BMC Neuroscience, 2010
Background The cerebellum is the neural structure with the highest levels of nitric oxide, a neurotransmitter that has been proposed to play a key role in the brain aging, although knowledge concerning its contribution to cerebellar senescence is still ...
Martinez-Lara Esther, Rus Alma, Jimenez Ana, Hernandez Raquel, Del Moral Maria L, Castro Lourdes, Molina Francisco J, Blanco Santos, Siles Eva, Peinado Maria A   +9 more
doaj   +1 more source