Results 21 to 30 of about 1,306,598 (296)

The modulation of neuroinflammation by inducible nitric oxide synthase. [PDF]

open access: yesJ Cell Commun Signal, 2022
The accumulation and propagation of misfolded proteins in the brain is a pathological hallmark shared by many neurodegenerative diseases, such as the depositions of β-amyloid and hyperphosphorylated tau proteins in Alzheimer's disease. Initial evidence shows the role of nitric oxide synthases in the development of neurodegenerative diseases.
Justo AFO, Suemoto CK.
europepmc   +3 more sources

The analgesic effect of early hyperbaric oxygen treatment in chronic constriction injury rats and its influence on nNOS and iNOS expression and inflammatory factor production

open access: yesMolecular Pain, 2018
Objective To observe the analgesic effect of early hyperbaric oxygen (HBO) treatment in chronic constriction injury (CCI) rats, and to analyze the influence of HBO on the expression of neuronal nitric oxide synthase and inducible nitric oxide synthase ...
Yuanyuan Ding   +6 more
doaj   +1 more source

A Study of the Antioxidant and Anti-Inflammatory Effects of Dusokohwaeum

open access: yesJournal of Acupuncture Research, 2023
Background: The aim of this study is to determine the antioxidant and anti-inflammatory effects of Dusokohwaeum (DOE). Methods: To measure the antioxidant and anti-inflammatory effects of DOE, the total flavonoid and polyphenol contents and radical ...
Yun-Gwon Seon   +7 more
doaj   +1 more source

Phototriggering Nitric Oxide Synthase from Geobacillus stearothermophilus [PDF]

open access: yes, 2012
Nitric oxide synthases (NOS) produce L-citrulline and nitric oxide (NO) in two turnovers from L-arginine via the bound intermediate, N-hydroxy-L-arginine.
Keller, Gretchen Eva   +1 more
core   +1 more source

Inducible nitric oxide synthase links NF-κB to PGE2 in polyunsaturated fatty acid altered fibroblast in-vitro wound healing

open access: yesLipids in Health and Disease, 2005
Background This study investigated mechanisms of altered fibroblast collagen production induced by polyunsaturated fatty acids. 3T3-Swiss fibroblasts were grown in medium containing either eicosapentaenoic or arachidonic acid.
Turek John J, Jia Yi
doaj   +1 more source

Role of Dietary Polyphenols in the Activity and Expression of Nitric Oxide Synthases: A Review

open access: yesAntioxidants, 2023
Nitric oxide (NO) plays several key roles in the functionality of an organism, and it is usually released in numerous organs and tissues. There are mainly three isoforms of the enzyme that produce NO starting from the metabolism of arginine, namely ...
Gabriele Serreli, Monica Deiana
doaj   +1 more source

Inducible Nitric Oxide Synthase and Inflammatory Diseases [PDF]

open access: yesMolecular Medicine, 2000
Nitric oxide (NO) is a colorless gas at room temperature and one of the simplest molecules known, yet it has been implicated in a wide variety of regulatory mechanisms ranging from vasodilatation and blood pressure control to neurotransmission. It is also involved in nonspecific immunity and participates in the complex mechanism of tissue injury as a ...
R, Zamora, Y, Vodovotz, T R, Billiar
openaire   +2 more sources

Metabolites content of stable forms of nitric oxide in the lungs of guinea pigs with experimental allergic alveolitis in different periods of its formation

open access: yesJournal of Education, Health and Sport, 2017
In this paper was found that the conditions for the development of experimental allergic alveolitis on the 44-th day increased the activity of inducible nitric oxide synthase and stable forms of nitric oxide metabolites.
M. S. Reheda   +2 more
doaj   +3 more sources

The protective effects of tadalafil on renal damage following ischemia reperfusion injury in rats

open access: yesKaohsiung Journal of Medical Sciences, 2015
Ischemia-reperfusion injury can cause renal damage, and phosphodiesterase inhibitors are reported to regulate antioxidant activity. We investigated the prevention of renal damage using tadalafil after renal ischemia reperfusion (I/R) injury in rats.
Bulent Erol   +9 more
doaj   +1 more source

Myelin basic protein peptide 45–89 induces the release of nitric oxide from microglial cells. [PDF]

open access: yes, 2002
Continuous (24 h) exposure of mixed oligodendrocyte/microglial cells to peptides 45–89 derived from citrullinated C8 isoforms of myelin basic protein (MBP) induces cell death.
Pichkhadze, B.   +4 more
core   +5 more sources

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