Results 31 to 40 of about 1,306,598 (296)

Neuronal and inducible nitric oxide synthase upregulation in the rat medial prefrontal cortex following acute restraint stress: A dataset

Data in Brief, 2016
This data article provides additional evidence on gene expression changes in the neuronal and inducible isoforms of nitric oxide synthase in the medial prefrontal cortex following acute stress.
Jereme G. Spiers, Hsiao-Jou Cortina Chen, Johnny K. Lee, Conrad Sernia, Nickolas A. Lavidis   +4 more
doaj   +1 more source

Anti-inflammatory effects of Torin2 on lipopolysaccharide-treated RAW264.7 murine macrophages and potential mechanisms

Heliyon, 2022
Context: Torin2 has various pharmacological properties. However, its anti-inflammatory activity has not been reported. Objective: This study focused on the potential anti-inflammatory properties of Torin2 in lipopolysaccharide (LPS)-evoked RAW264.7 ...
Shanshan Wei, Ting Wang, Qi Cao, Xue Chen, Zhiyong Chu, Zhenzhen Zhang   +5 more
doaj   +1 more source

Effects of nitric oxide synthase inhibitor - Nitro-L-Arginine Methyl Ester, on silica-inducated inflammatory reaction and apoptosis [PDF]

, 2006
BACKGROUND: Although nitric oxide is overproduced by macrophages and neutrophils after exposure to silica, its role in silica-induced inflammatory reaction and apoptosis needs further clarification.
He Wang, Wang, He, Leigh, James, Leigh James, James Leigh, Wang He   +5 more
core   +1 more source

Correlation Between Endothelial Dysfunction and Left Ventricular Remodeling in Patients with Chronic Kidney Disease

Kidney & Blood Pressure Research, 2014
Background/Aims: To investigate the role of endothelial dysfunction on left ventricular remodeling in patients with chronic kidney disease and to evaluate the correlation between endothelial dysfunction and left ventricular remodeling.
Tao Peng, Zhao Hu, Ling Wu, Dengren Li, Xiangdong Yang   +4 more
doaj   +1 more source

Potential anti-inflammatory activity of walnut protein derived peptide leucine-proline-phenylalanine in lipopolysaccharides-irritated RAW264.7 cells

Food and Agricultural Immunology, 2021
The purpose of this study was to explore the anti-inflammatory mechanism of walnut peptide LPF in the LPS-induced RAW264.7 cells model. The walnut peptide LPF down-regulated the phagocytic ability and the production of nitric oxide (NO) induced by LPS ...
Qinghua Wang, Tongxin Zhi, Panpan Han, Siting Li, Junxia Xia, Zhou Chen, Chong Wang, Yongling Wu, Yingmin Jia, Aijin Ma   +9 more
doaj   +1 more source

Insulin-stimulated phosphorylation of endothelial nitric oxide synthase at serine-615 contributes to nitric oxide synthesis [PDF]

, 2009
Insulin stimulates endothelial NO (nitric oxide) synthesis via PKB (protein kinase B)/Akt-mediated phosphorylation and activation of eNOS (endothelial NO synthase) at Ser-1177.
Boyd, Alasdair R., Stuart A. Ritchie, Ian P. Salt, Salt, Ian P., Kohlhaas, Christine F, Yalla, Krishna C, Kohlhaas, Christine F., Boyd, Alasdair R, Krishna C. Yalla, Walsh, Kenneth, Ritchie, Stuart A, John M. C. Connell, Christine F. Kohlhaas, Kenneth Walsh, Ritchie, Stuart A., Connell, John M.C., Connell, John Mc, Salt, Ian P, Alasdair R. Boyd, Yalla, Krishna C.   +19 more
core   +1 more source

Redox Couples of Inducible Nitric Oxide Synthase [PDF]

Journal of the American Chemical Society, 2005
We report direct electrochemistry of the iNOS heme domain in a DDAB film on the surface of a basal plane graphite electrode. Cyclic voltammetry reveals FeIII/II and FeII/I couples at -191 and -1049 mV (vs Ag/AgCl). Imidazole and carbon monoxide in solution shift the FeIII/II potential by +20 and +62 mV, while the addition of dioxygen results in large ...
Udit, Andrew K., Belliston-Bittner, Wendy, Glazer, Edith C., Nguyen, Yen Hoang Le, Gillan, James M., Hill, Michael G., Marletta, Michael A., Goodin, David B., Gray, Harry B.   +8 more
openaire   +3 more sources

Estrogen stimulates dimethylarginine dimethylaminohydrolase activity and the metabolism of asymmetric dimethylarginine. [PDF]

, 2003
Background— Experimental evidence suggests that estrogens stimulate the production of nitric oxide (NO) by vascular endothelial cells. This effect has been attributed to increased expression and enzymatic activity of both the constitutive and inducible ...
Cartwright, JE, Stephen S. Nussey, Whitley, GS, Guy St J. Whitley, Holden, DP, Desmond P. Holden, Nussey, SS, Judith E. Cartwright   +7 more
core   +1 more source

Inducible Nitric Oxide Synthase and Blood Pressure [PDF]

Hypertension, 1998
Abstract —In the present studies, the influence of inducible nitric oxide synthase (NOS) inhibition with aminoguanidine on renal function and blood pressure was examined in rats. Intravenous aminoguanidine infusion (60 mg · kg −1 · hr −1 ) for 40 minutes to anesthetized Sprague ...
D L, Mattson, C Y, Maeda, T D, Bachman, A W, Cowley   +3 more
openaire   +2 more sources

Male gender predisposes to development of endotoxic shock in the rat [PDF]

, 2000
Objective: After intravenous (i.v.) injection of lipopolysaccharide (LPS) macrophages release nitric oxide (NO) due to the expression of the inducible NO synthase (iNOS).
Kriston, Tünde, Hamar, Péter, Losonczy, György, Baylis, C., Harvey, J., Müller, Veronika, Szabó, Attila József, Heemann, Uwe   +7 more
core   +1 more source