Results 1 to 10 of about 1,509,178 (304)

The role of caveolae in endothelial dysfunction

Medical Review, 2021
Caveolae, the specialized cell-surface plasma membrane invaginations which are abundant in endothelial cells, play critical roles in regulating various cellular processes, including cholesterol homeostasis, nitric oxide production, and signal ...
He Jinlong, Cui Zhen, Zhu Yi
doaj   +1 more source

Correlation Between Endothelial Dysfunction and Left Ventricular Remodeling in Patients with Chronic Kidney Disease

Kidney & Blood Pressure Research, 2014
Background/Aims: To investigate the role of endothelial dysfunction on left ventricular remodeling in patients with chronic kidney disease and to evaluate the correlation between endothelial dysfunction and left ventricular remodeling.
Tao Peng, Zhao Hu, Ling Wu, Dengren Li, Xiangdong Yang   +4 more
doaj   +1 more source

Is there a relationship between endothelial nitric oxide synthase gene polymorphisms and ankylosing spondylitis?

Clinics
OBJECTIVE: Nitric oxide is produced by endothelial nitric oxide synthase, and its production can be influenced by polymorphisms of the endothelial nitric oxide synthase gene.
Ismail Sari, Yusuf Ziya Igci, Gercek Can, Ali Taylan, Dilek Solmaz, Bulent Gogebakan, Servet Akar, Zeynep Eslik, Giray Bozkaya, Nurullah Akkoc   +9 more
doaj   +1 more source

Evaluation of serum nitric oxide synthase levels in patients with coronary slow flow based on corrected TIMI frame count

Archives of Medical Science: Atherosclerotic Diseases, 2023
Introduction The coronary slow flow phenomenon (CSFP) finding in angiography is characterized by the delayed filling of the terminal vessels without significant epicardial coronary disease.
Jamal Shamsara, Sepideh Elyasi, Mostafa Dastani, Nadia Behzadian, Hesamoddin Hosseinjani, Mahshid Ataei, Fatemeh Jafari, Mahdi Akbarzadeh, Mahshid Naserifar, Amirhossein Sahebkar, Amir Hooshang Mohammadpour   +10 more
doaj   +1 more source

Relationship of endothelial nitric oxide synthase gene polymorphism with atherosclerotic coronary and carotid arterial disease in Egyptian population

The Egyptian Heart Journal, 2015
Introduction: Atherosclerosis is partly a heritable disorder. Various genetic polymorphisms have been linked to the atherosclerotic process and its complications. Glu298Asp polymorphism of endothelial nitric oxide synthase gene is one such genetic marker
Hany Younan, Gomaa Abdel Razek, Khaled Elkhashab, Howyda Abdelrasol, Mohammed Saad   +4 more
doaj   +1 more source

Metformin promotes angiogenesis and functional recovery in aged mice after spinal cord injury by adenosine monophosphate-activated protein kinase/endothelial nitric oxide synthase pathway

Neural Regeneration Research, 2023
Treatment with metformin can lead to the recovery of pleiotropic biological activities after spinal cord injury. However, its effect on spinal cord injury in aged mice remains unclear.
Jin-Yun Zhao, Xiao-Long Sheng, Cheng-Jun Li, Tian Qin, Run-Dong He, Guo-Yu Dai, Yong Cao, Hong-Bin Lu, Chun-Yue Duan, Jian-Zhong Hu   +9 more
doaj   +1 more source

O‐GlcNAcylation Mediates Glucose‐Induced Alterations in Endothelial Cell Phenotype in Human Diabetes Mellitus

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Posttranslational protein modification with O‐linked N‐acetylglucosamine (O‐GlcNAc) is linked to high glucose levels in type 2 diabetes mellitus (T2DM) and may alter cellular function.
Nobuyuki Masaki, Bihua Feng, Rosa Bretón‐Romero, Elica Inagaki, Robert M. Weisbrod, Jessica L. Fetterman, Naomi M. Hamburg   +6 more
doaj   +1 more source

Premature Myocardial Infarction: Genetic Variations in SIRT1 Affect Disease Susceptibility

Cardiology Research and Practice, 2019
Objectives. Premature myocardial infarction (PMI) is an uncommon disease, and its incidence varies between 2% and 10%, rising, depending on genetic susceptibility under the influence of lifestyle.
Aylin Hatice Yamac, Omer Uysal, Ziya Ismailoglu, Mehmet Ertürk, Mert Celikten, Ahmet Bacaksiz, Ulkan Kilic   +6 more
doaj   +1 more source

Analysis of the relationship between the activity of inducible nitric oxide synthase and interleukin-1 in the pathogenesis of experimental diabetic retinopathy

Journal of Education, Health and Sport, 2020
The purpose of the study: analysis of changes in the development of hypoxia and endothelial dysfunction in experimental diabetic retinopathy. Our results indicate endothelial dysfunction and dysfunction of nitric oxide synthesis on the 30th day of ...
Ya. V. Sirman, I. V. Savytskyi
doaj   +1 more source

Role of Dietary Polyphenols in the Activity and Expression of Nitric Oxide Synthases: A Review

Antioxidants, 2023
Nitric oxide (NO) plays several key roles in the functionality of an organism, and it is usually released in numerous organs and tissues. There are mainly three isoforms of the enzyme that produce NO starting from the metabolism of arginine, namely ...
Gabriele Serreli, Monica Deiana
doaj   +1 more source