Loss of inducible nitric oxide synthase promotes Kras/Pten-driven lung tumorigenesis. [PDF]
Kabiri Z +4 more
europepmc +1 more source
The Endothelial CXCR Family in Vascular Health and Disease
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu +4 more
wiley +1 more source
Nitric oxide synthase activation in nTS is essential to NMDA receptor dependent encoding of the cough reflex. [PDF]
Farmer DGS +3 more
europepmc +1 more source
Thin endometrium upregulates Cxcl11, which polarizes ovarian macrophages via NF‐κB/AKT, impairing ovarian function. A new uter‐ovarian signaling axis is identified. ABSTRACT Objective Thin endometrium (TE) is a recognized cause of female infertility, primarily associated with impaired uterine receptivity.
Yulu Yang +8 more
wiley +1 more source
Dynamic tail amine interactions drive isoform selectivity for potent human neuronal nitric oxide synthase inhibitors. [PDF]
Awasthi A, Kang KM, Silverman RB.
europepmc +1 more source
Metrnl: A Novel Therapeutic Target in Atherosclerosis
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley +1 more source
Oral pathogens reprogram endothelial barrier and angiotensin-converting enzyme2/endothelial nitric oxide synthase-nitric oxide signaling to promote blood pressure dysregulation. [PDF]
Hsieh MS +6 more
europepmc +1 more source
Bisphenol A and Its Analogs: Toxicity Analysis in Mouse and Rat Liver—A Review
ABSTRACT Bisphenol A (BPA) and its analogs are widely recognized for their use in industry and plastic manufacturing. Consequently, humans and animals are continually exposed to various substances in their daily lives. This review evaluates the hepatic toxicity of BPA and its analogs in mice and rats, with particular emphasis on molecular mechanisms ...
Sevda Bagdatli +5 more
wiley +1 more source
Nitric Oxide Synthase 2 (NOS2) Gene Polymorphisms Association With Risk of Pulmonary Tuberculosis (PTB): A Case-Control Study. [PDF]
Alijani E +7 more
europepmc +1 more source
Electronic structure and orbital interactions of intermediates throughout electrochemically catalyzed CO2‐to‐CO reduction reaction by iron porphyrin are carefully discussed by DFT calculations in this work. The results demonstrate distinct functions of Fe 3d orbitals and porphyrin π* orbitals for electron transfer process to CO2, and the electronic ...
Ching‐Chin Chen
wiley +1 more source

