Results 161 to 170 of about 437,208 (310)

ENDOTHELIAL NITRIC OXIDE SYNTHASE AND ANGIOTENSIN II TYPE 1 RECEPTOR GENE POLYMORPHISMS CAN INFLUENCE CHRONIC INFLAMMATORY STATE IN RENAL TRANSPLANT PATIENTS

open access: bronze, 2004
Siren Sezer   +6 more
openalex   +1 more source

Immunomodulatory natural polysaccharide‐based nanoparticles for the treatment of neurodegenerative diseases

open access: yesIbrain, EarlyView.
Polysaccharide‐based nanoparticles offer versatile platforms for drug delivery and immune modulation in neurodegenerative diseases. This review highlights their potential in treating Alzheimer's, Parkinson's, and multiple sclerosis, focusing on targeted delivery and neuroinflammation.
Leto‐Aikaterini Tziveleka   +5 more
wiley   +1 more source

Identification of crucial genes for polycystic ovary syndrome and atherosclerosis through comprehensive bioinformatics analysis and machine learning

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To identify potential biomarkers in patients with polycystic ovary syndrome (PCOS) and atherosclerosis, and to explore the common pathologic mechanisms between these two diseases in response to the increased risk of cardiovascular diseases in patients with PCOS.
Lirong Wang   +7 more
wiley   +1 more source

Association analysis of genetic variations of eNOS and α2ß1 integrin genes with type 2 diabetic retinopathy

open access: yesThe Application of Clinical Genetics, 2012
Rania Azmy,1 Ashraf Dawood,1 Ayman Kilany,1 Yasser El-Ghobashy,1 Amin Faisal Ellakwa,2 May El-Daly31Medical Biochemistry Department, 2Ophthalmology Department, Faculty of Medicine, 3National Liver Institute, Menoufiya University, Shebin Elkom ...
Azmy R   +5 more
doaj  

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

open access: yesiMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu   +8 more
wiley   +1 more source

ROS and endothelial nitric oxide synthase (eNOS)-dependent trafficking of angiotensin II type 2 receptor begets neuronal NOS in cardiac myocytes [PDF]

open access: green, 2015
Ji Hyun Jang   +9 more
openalex   +1 more source

The influence of microbiome‐derived amino acids metabolites in shaping the glioma immunosuppressive microenvironment

open access: yesInterdisciplinary Medicine, EarlyView.
Left: The disruption of the balance between carcinogenic bacteria and probiotics mediated by antibiotics, protein, and glucose intake. Middle: The gut microbiota‐derived amino acids, primarily through tryptophan, tyrosine, arginine, and branched‐chain amino acid pathways, regulate glioma development via mechanisms such as AHR activation, metabolic ...
Qianquan Ma   +10 more
wiley   +1 more source

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