Results 151 to 160 of about 93,042 (311)

Fisiopatologia de la cèl·lula endotelial en la cirrosi hepàtica [PDF]

, 2008
[cat] La cirrosi hepàtica constitueix un estadi de fibrosi hepàtica irreversible que es produeix com a resposta a un dany hepàtic prolongat i que té com a conseqüència l'acumulació de teixit connectiu al fetge degut a un desequilibri important entre la ...
Tugues Solsona, Sònia
core  

Analysis of the risk factors impact on the life quality of patients with arterial hypertension

Endocrine Regulations
Objective. Recently, multicomponent quality-of-life indicators have become increasingly important in monitoring the health status of patients with hypertension and evaluating the effectiveness of treatment. Improving patient quality of life is considered
Pidruchna Svitlana, Yarema Nadiya, Kuzmak Iryna, Prokopovych Olena, Shmanko Volodymyr, Shmanko Oleh, Lykhatskyi Petro, Ostrivka Oksana, Mudra Alla, Palytsya Lylya, Letniak Nataliya, Yaroshenko Tetyana, Pohorielova Oksana, Chernyshenko Olena   +13 more
doaj   +1 more source

Dual Regulatory Functions of Classical Zinc Finger Clusters from Myeloid Zinc Finger‐1

Chemistry – A European Journal, EarlyView.
The classical zinc finger (ZF) protein MZF1 uses two ZF clusters to achieve metal‐dependent and gene‐specific promoter recognition. The differential redox stability and modular utilization of the two ZF clusters enable MZF1 to regulate cerebrovascular, neuronal, and cancer‐related transcriptional programs.
Yunha Hwang, Yerim Park, Nohwan Park, Heeju Noh, Hyun Goo Kang, Seung Jae Lee   +5 more
wiley   +1 more source

Influência de vias dependentes do óxido nítrico presentes na substância cinzenta periaquedutal dorso-lateral no efeito ansiolítico do álcool [PDF]

, 2002
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Farmacologia.Nesse estudo foi avaliado o envolvimento do [óxido nítrico] (NO) presente na [substância cinzenta periaquedutal ...
Ortiga, Roberta Moura
core  

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

CARDIOVASCULAR AND METABOLIC ADAPTATION TO PREGNANCY IN SPONTANEOUSLY HYPERTENSIVE RATS [PDF]

, 2008
Molti ormoni sono coinvolti nell’omeostasi dell’organismo innescando e sostenendo meccanismi di protezione e di adattamento in risposta a cambiamenti fisiopatologici e a stress metabolici, fisici, infiammatori, infettivi sia acuti che cronici.
Iacono, Anna
core  

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Gene Transfer of Calcitonin Gene-Related Peptide Inhibits Macrophages and Inflammatory Mediators in Vein Graft Disease [PDF]

, 2008
Vein graft disease is a chronic inflammatory disease and limits the late results of coronary revascularization. Calcitonin gene-related peptide (CGRP) inhibits macrophages infiltrated and inflammatory mediators, we hypothesized that transfected CGRP gene
Jian Zhuang, Hongsui Wu, Shiliang Chen, Jian Su, Yuhui Zheng, Xiaoning Zhang, Jianguang Chen, Huanxin Yang, Zhihong Chen   +8 more
core   +1 more source