Results 231 to 240 of about 437,208 (310)

DmdA‐independent lag phase shortening in Phaeobacter inhibens bacteria under stress conditions

open access: yesThe FEBS Journal, EarlyView.
The lag phase is crucial for resuming bacterial growth and can be shortened by fueling the methionine cycle with methyl groups from DMSP or other methylated compounds. While DmdA is the primary DMSP demethylase in Phaeobacter inhibens, stress activates additional enzymes like Bmt. This enzymatic flexibility allows bacteria to exit the lag phase rapidly,
Delia A. Narváez‐Barragán   +2 more
wiley   +1 more source

Relationship Between Periodontitis and Nitric Oxide in Patients Undergoing Maintenance Hemodialysis

open access: yesHemodialysis International, EarlyView.
ABSTRACT Background The inflammatory processes associated with periodontitis have been implicated in the development and progression of systemic diseases, including chronic kidney disease (CKD). Notably, individuals with CKD frequently exhibit shared risk factors with those affected by periodontitis, such as hypertension, smoking, and diabetes mellitus.
Gabriela Keiko Izumi   +7 more
wiley   +1 more source

Molecular Mechanisms of Type 2 Diabetes-Related Heart Disease and Therapeutic Insights. [PDF]

open access: yesInt J Mol Sci
Giraldo-Gonzalez GC   +3 more
europepmc   +1 more source

The loss of the urea cycle and ornithine metabolism in different insect orders: An omics approach

open access: yesInsect Molecular Biology, EarlyView.
Among urea cycle enzymes, only the nitric oxide synthase gene is universally present across insect genomes. All Hemiptera species lack the enzymes needed to convert citrulline to arginine, and some also lack the pathway from arginine to ornithine. Putrescine and spermidine synthesis is conserved in all insects, but aphids lack the capability to produce
Jessica Cristina Silva Martins   +7 more
wiley   +1 more source

The Landscape of SPP1+ Macrophages Across Tissues and Diseases: A Comprehensive Review

open access: yesImmunology, EarlyView.
SPP1+ macrophages represent a conserved, disease‐associated population present across cancerous and non‐cancerous conditions, involved in immunosuppression, fibrosis, lipid metabolism, phagocytosis, and other cellular processes. This review highlights their shared molecular programmes across tissues, their interactions with stromal and immune cells ...
Alessandro Palma
wiley   +1 more source

Identifying iNOS and glycogen as biomarkers for degenerated cerebellar purkinje cells in autism spectrum disorder: Protective effects of erythropoietin and zinc sulfate. [PDF]

open access: yesPLoS One
Al-Garni AM   +12 more
europepmc   +1 more source

Canagliflozin protects cardiovascular function in type 2 diabetic coronary artery disease by regulating natriuretic peptide B

open access: yesJournal of Diabetes Investigation, EarlyView.
Canagliflozin regulated the cyclic guanosine monophosphate (cGMP)‐protein kinase 1‐α signaling pathway through the natriuretic peptide B gene, thereby improving cell viability, apoptosis, and reactive oxygen species levels, and ultimately protecting cardiac function in type 2 diabetic patients with coronary artery disease.
Jiarui Zhang   +5 more
wiley   +1 more source

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