Results 111 to 120 of about 57,731 (238)

Tumor‐Regional Immune Microenvironment: A Critical Factor in the Design of Radiotherapy–Immunotherapy Combination Trials

International Journal of Cancer, EarlyView.
ABSTRACT Clinical trials combining radiotherapy (RT) with immune checkpoint blockade (ICB) have shown improved outcomes in only a fraction of patients, and optimal strategies for integrating these modalities remain under intense investigation. With a few exceptions, phase III combination trials have yielded disappointing results.
Xuanwei Zhang, Hui Wang, Weiyan Tang, Kai Kang, Kateryna Onyshchenko, Taotao Huang, Dan Liu, Jianxin Xue, You Lu, Gabriele Niedermann, Ren Luo   +10 more
wiley   +1 more source

MicroRNA-155 at the crossroads of inflammation and vascular dysfunction in essential hypertension. [PDF]

Mol Biol Rep
Salamt N, Che Roos NA, Mohamed Shakrin NNS, Ugusman A.   +3 more
europepmc   +1 more source

MicroRNA‐210 level as a biomarker for pre‐eclampsia severity: A systematic review and meta‐analysis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Pre‐eclampsia is a serious pregnancy‐related syndrome lacking accurate prognostic markers. MicroRNA‐210, overexpressed in the circulation of women with pre‐eclampsia, has recently emerged as a promising biomarker. Objectives We conducted a systematic review and meta‐analysis to evaluate the relationship between miR‐210 levels and ...
Dávid Márai, Isabel Pinto Amorim das Virgens, Ádám Vincze, Mahmoud Obeidat, Péter Hegyi, Mikolt Bakony, Zsófia Réka Erdélyi, Zsolt Melczer, Sándor Valent   +8 more
wiley   +1 more source

Evaluation of Serum Adipocytokines and Cystatin C As Early Biomarkers in Chronic Kidney Disease Patients and Their Relation to Endothelial Dysfunction. [PDF]

Cureus
Bagewadi HG, Patil S, Sugoor M, Melkundi RS, A S, Kallur R, Tondare SB.   +6 more
europepmc   +1 more source

Maternal and infant gut microbiome

iMeta, EarlyView.
The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang, Felicia Tin, Hui Chen, Fuxin Jiao, Min Wu, Shanshan Sun, Lisha Lin, Die Li, Huimin Zheng, Zhenxin Niu, Mengyao Lan, Bahtiyar Yilmaz, Johan G. Eriksson, Mengjia Wang, Andrew Macpherson, Jose C. Clemente, Jia Xu, Ri‐hua Xie, Xiaojiao Zheng, Tao Zhou, Jinfeng Wang, Wei Shen, Bing Huang, Xia Chen, Hai Li, Yan He   +25 more
wiley   +1 more source

Relationship Between eNOS T-786C and G894T Polymorphisms and Colorectal Cancer Susceptibility: A Study in the Algerian Population. [PDF]

Int J Mol Sci
Djaballah-Ider FZ, Gouaref I, Seghirate A, Touil-Boukoffa C, Galleze A.   +4 more
europepmc   +1 more source

The plant microbiome: From ecological foundations to precision microbial engineering for sustainable agriculture

iMeta, EarlyView.
From ecological principles to precision engineering of plant microbiomes for sustainable agriculture. The plant holobiont integrates diverse microbial niches (including rhizosphere, endosphere, phyllosphere, seed, and aerial‐root mucilagesphere), host genetics (namely M genes), and host metabolites. Furthermore, molecular dialogues, including rhizobial
Mi Wei, Tengxiang Lian, Liying Chen, Lanxiang Wang, Junjie Ye, Xiaofang Yao, Shilong Duan, Ziyu Lu, Jinji Tu, Hongfu Li, Xin‐Yue Xu, Jie Zhou, Junliang He, Feiying Zhu, Paola Bonfante, Lam‐Son Phan Tran, Zhiqiang Pang, Xin Zhou, Zhihui Xu, Lin Zhang, Mengcen Wang, Xiaolin Wang, Chang‐Fu Tian, Yong‐Xin Liu, Kai Sun, Ertao Wang, Xianan Xie   +26 more
wiley   +1 more source

Chronic simultaneous inducible nitric oxide synthase (iNOS) and peripheral cannabinoid CB₁ receptors blockade ameliorates pulmonary hypertension in monocrotaline-induced rat model. [PDF]

Front Pharmacol
Ryszkiewicz P, Remiszewski P, Pędzińska-Betiuk A, Mińczuk K, Baranowska-Kuczko M, Weresa J, Malinowska B.   +6 more
europepmc   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Unmet Need to Verify Coronary Artery Spasm in Patients with Chronic or Acute Coronary Syndrome and Non-Obstructive Coronary Arteries. [PDF]

Life (Basel)
Hung MJ, Hung MY.
europepmc   +1 more source