Results 31 to 40 of about 60,817 (284)

Exploring Supramolecular Assembly Space of Cationic 1,2,4-Selenodiazoles: Effect of the Substituent at the Carbon Atom and Anions

Molecules, 2022
Chalcogenodiazoles have been intensively studied in recent years in the context of their supramolecular chemistry. In contrast, the newly discovered cationic 1,2,4-selenodiazole supramolecular building blocks, which can be obtained via coupling between 2-
Mariya V. Grudova, Alexey S. Kubasov, Victor N. Khrustalev, Alexander S. Novikov, Andreii S. Kritchenkov, Valentine G. Nenajdenko, Alexander V. Borisov, Alexander G. Tskhovrebov   +7 more
doaj   +1 more source

Simple synthesis of pyrrolo[3,2-e]indole-1-carbonitriles

Beilstein Journal of Organic Chemistry, 2013
Alkylation of 5-nitroindol-4-ylacetonitriles with ethyl chloroacetate, α-halomethyl ketones, and chloroacetonitrile followed by a treatment of the products with chlorotrimethylsilane in the presence of DBU gives 1-cyanopyrrolo[3,2-e]indoles substituted ...
Adam Trawczyński, Robert Bujok, Zbigniew Wróbel, Krzysztof Wojciechowski   +3 more
doaj   +1 more source

Cyclic Nitriles:  Diastereoselective Alkylations [PDF]

The Journal of Organic Chemistry, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Fraser F, Fleming, Subrahmanyam, Gudipati, Zhiyu, Zhang, Wang, Liu, Omar W, Steward   +4 more
openaire   +2 more sources

Recent advances and perspectives in ruthenium-catalyzed cyanation reactions

Beilstein Journal of Organic Chemistry, 2022
The cyanation reaction has achieved rapid progress in recent times. The ability to exhibit multiple oxidation states increased the demand of ruthenium in the field of catalysis.
Thaipparambil Aneeja, Cheriya Mukkolakkal Abdulla Afsina, Padinjare Veetil Saranya, Gopinathan Anilkumar   +3 more
doaj   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

An unprecedented palladium-arsenic catalytic cycle for nitriles hydration

Frontiers in Chemistry, 2023
An unprecedented palladium/arsenic-based catalytic cycle for the hydration of nitriles to the corresponding amides is here described. It occurs in exceptionally mild conditions such as neutral pH and moderate temperature (60°C).
Damiano Cirri, Tiziano Marzo, Alessandro Pratesi   +2 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Enable biomass-derived alcohols mediated alkylation and transfer hydrogenation

Nature Communications
A single-atom catalyst with generally regarded inert Zn–N4 motifs derived from ZIF-8 is unexpectedly efficient for the activation of alcohols, enabling alcohol-mediated alkylation and transfer hydrogenation. C-alkylation of nitriles, ketones, alcohols, N-
Xixi Liu, Liang Huang, Yuandie Ma, Guoqiang She, Peng Zhou, Liangfang Zhu, Zehui Zhang   +6 more
doaj   +1 more source

Conversion of Natural Aldehydes from Eucalyptus citriodora, Cymbopogon citratus, and Lippia multiflora into Oximes: GC-MS and FT-IR Analysis †

Molecules, 2009
Three carbonyl-containing extracts of essential oils from Eucalyptus citriodora (Myrtaceae), Cymbopogon citratus (Gramineae) and Lippia multiflora (Verbenaceae) were used for the preparation of oximes.
Igor W. Ouédraogo, Michael Boulvin, Robert Flammang, Pascal Gerbaux, Yvonne L. Bonzi-Coulibaly   +4 more
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source