Results 51 to 60 of about 64,062 (284)

Recent advances and perspectives in ruthenium-catalyzed cyanation reactions

Beilstein Journal of Organic Chemistry, 2022
The cyanation reaction has achieved rapid progress in recent times. The ability to exhibit multiple oxidation states increased the demand of ruthenium in the field of catalysis.
Thaipparambil Aneeja, Cheriya Mukkolakkal Abdulla Afsina, Padinjare Veetil Saranya, Gopinathan Anilkumar   +3 more
doaj   +1 more source

Selective NaOH-catalysed hydration of aromatic nitriles to amides [PDF]

, 2015
The authors gratefully acknowledge the Royal Society (University Research Fellowship to CSJC)The selective synthesis of aromatic and heteroaromatic amides through base-catalysed hydration of nitriles was achieved using inexpensive and commercially ...
Cazin, Catherine S.J., Gomez Herrera, Alberto, Nahra, Fady, Révolte , Antoine, Schmid, Thibault, Sneddon , Deborah, Songis, Olivier   +6 more
core   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Enable biomass-derived alcohols mediated alkylation and transfer hydrogenation

Nature Communications
A single-atom catalyst with generally regarded inert Zn–N4 motifs derived from ZIF-8 is unexpectedly efficient for the activation of alcohols, enabling alcohol-mediated alkylation and transfer hydrogenation. C-alkylation of nitriles, ketones, alcohols, N-
Xixi Liu, Liang Huang, Yuandie Ma, Guoqiang She, Peng Zhou, Liangfang Zhu, Zehui Zhang   +6 more
doaj   +1 more source

Reaction between Indazole and Pd-Bound Isocyanides—A Theoretical Mechanistic Study

Molecules, 2018
The mechanism of the addition of indazole (Ind)—a bifunctional aromatic N,NH-nucleophile—to cyclohexyl isocyanide coordinated to the palladium(II) center in the model complex cis-[PdCl2(CNMe)(CNCy)] (1) to give the corresponding aminocarbene ...
Girolamo Casella, Maurizio Casarin, Vadim Yu. Kukushkin, Maxim L. Kuznetsov   +3 more
doaj   +1 more source

Sulfur-promoted, one-pot, and metal-free conversion of aromatic aldehydes to nitriles using an inorganic ammonium salt as the nitrogen source

Green Synthesis and Catalysis, 2023
A simple protocol for the sulfur-promoted conversion of aromatic aldehydes to aromatic nitriles has been developed. This strategy enables the one-pot conversion of inexpensive and readily available aromatic aldehydes into highly valuable aromatic ...
Jiawen Yin, Xia Meng, Changqun Cai, Lingyun Wang, Hang Gong   +4 more
doaj   +1 more source

Biological activity of glucosinolate derived compounds isolated from seed meal of Brassica crops and evaluated as plant and food protection agents [PDF]

, 2007
Glucosinolates are amino acid derived allelochemicals characteristic of plants of the order Capparales. These compounds are present in seeds of agriculturally common Brassica crops in varying quantities depending on the species (ref).
Bellostas, N., Casanova, E., Garcia-Mina, J.M., Hansen, L.M., Jørgensen, L.N., Kudsk, P., Madsen, P.H., Sørensen, H., Sørensen, J.C.   +8 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Synthetic Applications of the Parkins Nitrile Hydration Catalyst [PtH{(PMe2O)2H}(PMe2OH)]: A Review

Applied Sciences, 2015
The air-stable hydride-platinum(II) complex [PtH{(PMe2O)2H}(PMe2OH)], reported by Parkins and co-workers in 1995, is the most versatile catalyst currently available for the hydration of C≡N bonds.
Victorio Cadierno
doaj   +1 more source

Effect of dipole polarizability on positron binding by strongly polar molecules [PDF]

, 2015
A model for positron binding to polar molecules is considered by combining the dipole potential outside the molecule with a strongly repulsive core of a given radius.
Gribakin, G. F., Swann, A. R.
core   +2 more sources