Results 31 to 40 of about 44,003 (284)

Ahmad-Strong synthesis of 8-, 9-, and 10-pentadecynoic acids

open access: yesJournal of Lipid Research, 1969
Three pentadecynoic acids, with the triple bond in the 8-, 9-, and 10-positions, have been synthesized on a gram scale in over-all yield of 65% by refinements of the five-step Ahmad-Strong method; isolation of intermediates was shown to be unnecessary ...
David R. Howton, Robert A. Stein
doaj   +1 more source

Exploring Supramolecular Assembly Space of Cationic 1,2,4-Selenodiazoles: Effect of the Substituent at the Carbon Atom and Anions

open access: yesMolecules, 2022
Chalcogenodiazoles have been intensively studied in recent years in the context of their supramolecular chemistry. In contrast, the newly discovered cationic 1,2,4-selenodiazole supramolecular building blocks, which can be obtained via coupling between 2-
Mariya V. Grudova   +7 more
doaj   +1 more source

Simple synthesis of pyrrolo[3,2-e]indole-1-carbonitriles

open access: yesBeilstein Journal of Organic Chemistry, 2013
Alkylation of 5-nitroindol-4-ylacetonitriles with ethyl chloroacetate, α-halomethyl ketones, and chloroacetonitrile followed by a treatment of the products with chlorotrimethylsilane in the presence of DBU gives 1-cyanopyrrolo[3,2-e]indoles substituted ...
Adam Trawczyński   +3 more
doaj   +1 more source

Alkoxyallene‐Based LANCA Three‐Component Synthesis of 1,2‐Diketones, Quinoxalines, and Unique Isoindenone Dimers and a Computational Study of the Isoindenone Dimerization [PDF]

open access: yes, 2020
A series of β‐alkoxy‐β‐ketoenamides was prepared by the well‐established LANCA three‐component reaction of lithiated 1‐(2‐trimethylsilylethoxy)‐substituted allenes, nitriles, and α,β‐unsaturated carboxylic acids.
Bera M. K.   +6 more
core   +1 more source

Recent advances and perspectives in ruthenium-catalyzed cyanation reactions

open access: yesBeilstein Journal of Organic Chemistry, 2022
The cyanation reaction has achieved rapid progress in recent times. The ability to exhibit multiple oxidation states increased the demand of ruthenium in the field of catalysis.
Thaipparambil Aneeja   +3 more
doaj   +1 more source

Effect of ascorbic acid and glutathione on the production of nitriles by myrosinase [PDF]

open access: yes, 2006
Biofumigation is based on the use of glucosinolate-containing plants for the control of soil-borne pest and diseases. Upon tissue damage, glucosinolates are hydrolyzed by endogenous enzymes (myrosinase) and a range of biologically active compounds are ...
Bellostas, Natalia   +2 more
core  

Development of covalent triazine frameworks as heterogeneous catalytic supports [PDF]

open access: yes, 2019
Covalent triazine frameworks (CTFs) are established as an emerging class of porous organic polymers with remarkable features such as large surface area and permanent porosity, high thermal and chemical stability, and convenient functionalization that ...
Krishnaraj, Chidharth   +3 more
core   +1 more source

Cyclic Nitriles:  Diastereoselective Alkylations [PDF]

open access: yesThe Journal of Organic Chemistry, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Fraser F, Fleming   +4 more
openaire   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

An unprecedented palladium-arsenic catalytic cycle for nitriles hydration

open access: yesFrontiers in Chemistry, 2023
An unprecedented palladium/arsenic-based catalytic cycle for the hydration of nitriles to the corresponding amides is here described. It occurs in exceptionally mild conditions such as neutral pH and moderate temperature (60°C).
Damiano Cirri   +2 more
doaj   +1 more source

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