Results 1 to 10 of about 8,383 (210)

Efficacy of radical reactions of isocyanides with heteroatom radicals in organic synthesis [PDF]

Beilstein Journal of Organic Chemistry
Isocyanide is a promising synthetic reagent not only as a one-carbon homologation reagent but also as a nitrogen source for nitrogen-containing molecules.
Akiya Ogawa, Yuki Yamamoto
doaj   +2 more sources

Studies on the interaction of isocyanides with imines: reaction scope and mechanistic variations [PDF]

Beilstein Journal of Organic Chemistry, 2014
The interaction of imines with isocyanides has been studied. The main product results from a sequential process involving the attack of two units of isocyanide, under Lewis acid catalysis, upon the carbon–nitrogen double bond of the imine to form the 4 ...
Ouldouz Ghashghaei, Consiglia Annamaria Manna, Esther Vicente-García, Marc Revés, Rodolfo Lavilla   +4 more
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Synthesis of pyrrole-fused dibenzoxazepine/dibenzothiazepine/triazolobenzodiazepine derivatives via isocyanide-based multicomponent reactions [PDF]

Beilstein Journal of Organic Chemistry
An efficient and facile synthesis of pyrrole-fused dibenzoxazepine/dibenzothiazepine/triazolobenzodiazepine derivatives was developed through the isocyanide-based multicomponent reaction of isocyanides, gem-diactivated olefins, and cyclic imines such as ...
Marzieh Norouzi, Mohammad Taghi Nazeri, Ahmad Shaabani, Behrouz Notash   +3 more
doaj   +2 more sources

N-Halosuccinimide enables cascade oxidative trifluorination and halogenative cyclization of tryptamine-derived isocyanides [PDF]

Nature Communications
Both the pyrroloindoline core and N–CF3 moiety hold significant importance in medicinal chemistry. However, to date, no instances of constructing N–CF3-containing pyrroloindolines have been reported.
Jun-Yunzi Wu, Long-Ling Huang, Jia-Luo Fu, Jia-Yi Li, Shuang Lin, Shuang Yang, Zhi-Shu Huang, Honggen Wang, Qingjiang Li   +8 more
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A More Sustainable Isocyanide Synthesis from N-Substituted Formamides Using Phosphorus Oxychloride in the Presence of Triethylamine as Solvent

Molecules, 2022
A simple, green, and highly efficient protocol for the synthesis of isocyanides is described. The reaction involves dehydration of formamides with phosphorus oxychloride in the presence of triethylamine as solvent at 0 °C.
Sodeeq Aderotimi Salami, Xavier Siwe-Noundou, Rui Werner Maçedo Krause   +2 more
doaj   +1 more source

Synthesis of Chromeno[3,4-b]piperazines by an Enol-Ugi/Reduction/Cyclization Sequence

Molecules, 2021
Keto piperazines and aminocoumarins are privileged building blocks for the construction of geometrically constrained peptides and therefore valuable structures in drug discovery.
Ana Bornadiego, Ana G. Neo, Carlos F. Marcos   +2 more
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Ugi Reaction on α-Phosphorated Ketimines for the Synthesis of Tetrasubstituted α-Aminophosphonates and Their Applications as Antiproliferative Agents

Molecules, 2021
An Ugi three-component reaction using preformed α-phosphorated N-tosyl ketimines with different isocyanides in the presence of a carboxylic acid affords tetrasubstituted α-aminophosphonates.
Adrián López-Francés, Xabier del Corte, Edorta Martínez de Marigorta, Francisco Palacios, Javier Vicario   +4 more
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Using highly substituted isocyanides in the synthesis ofiminothiophenes fused to quinolines [PDF]

شیمی کاربردی روز, 2018
In this manuscript the reaction of 2-mercaptoquinoline-3-carbaldehydes and 1,1,3,3-tetramethyl butylisocyanide as highly substituted isocyanide in the reflux of ethanol without catalyst is described.
Morteza Shiri, shima fazelzadeh, Zeinab Faghihi, Behrouz Notash   +3 more
doaj   +1 more source

Synthesis of Depsipeptides via Isocyanide-Based Consecutive Bargellini–Passerini Multicomponent Reactions

SynOpen, 2021
An efficient and straightforward approach has been established for the preparation of a new class of depsipeptide structures via isocyanide-based consecutive Bargellini–Passerini multicomponent reactions.
Hassan Farhid, Mohammad Mahdi Rostami, Ahmad Shaabani, Behrouz Notash   +3 more
doaj   +1 more source

Radical Fluoroalkylation Reactions [PDF]

, 2018
Recent protocols and reactions for catalytic radical perfluoroalkylations will be described. The production of perfluoroalkyl radicals (RF = CnF2n+1, n ≥ 2), which effect both addition and substitution reactions on organic substrates, can be realized ...
Barata Vallejo, Sebastian, Cooke, María Victoria, Postigo, A.   +2 more
core   +1 more source