Results 41 to 50 of about 5,434 (218)

A Novel Method to Construct 2-Aminobenzofurans via [4 + 1] Cycloaddition Reaction of In Situ Generated Ortho-Quinone Methides with Isocyanides

Molecules, 2022
A new approach for the synthesis of 2-aminobenzofurans has been described via Sc(OTf)3 mediated formal cycloaddition of isocyanides with the in situ generated ortho-quinone methides (o-QMs) from o-hydroxybenzhydryl alcohol. Notably, as a class of readily
Huaxin Lin, Senling Tang, Yang Pan, Peng Liang, Xiaofeng Ma, Wei Jiao, Huawu Shao   +6 more
doaj   +1 more source

Isocyanide 2.0

Green Chemistry, 2020
Isocyanides are important chemicals, with limited availability, thus reducing their general use. Our highly improved isocyanide synthesis performed on mole to μ-mole scale, individually or in a 96-well parallel fashion enables unprecedented exploration of novel chemistries.
Pravin Patil, Maryam Ahmadian-Moghaddam, Alexander Dömling   +2 more
openaire   +3 more sources

One-step synthesis of imidazoles from Asmic (anisylsulfanylmethyl isocyanide)

Beilstein Journal of Organic Chemistry, 2021
Substituted imidazoles are readily prepared by condensing the versatile isocyanide Asmic, anisylsulfanylmethylisocyanide, with nitrogenous π-electrophiles.
Louis G. Mueller, Allen Chao, Embarek AlWedi, Fraser F. Fleming   +3 more
doaj   +1 more source

The Chemistry of Phenylimidotechnetium(V) Complexes with Isocyanides: Steric and Electronic Factors

Molecules, 2022
Organometallic approaches are of ongoing interest for the development of novel functional 99mTc radiopharmaceuticals, while the basic organotechnetium chemistry seems frequently to be little explored. Thus, structural and reactivity studies with the long-
Guilhem Claude, Laura Zeh, Maximilian Roca Jungfer, Adelheid Hagenbach, Joshua S. Figueroa, Ulrich Abram   +5 more
doaj   +1 more source

Click‐Spaltung quartärer Anilinium‐Tetrazine ermöglicht Kaskadenaufbau multifunktioneller biomolekularer Gerüste

Angewandte Chemie, EarlyView.
Die Click‐Chemie hat sich von dem Aufbau kovalenter Bindungen hin zum Spalten von Bindungen weiterentwickelt. Hier wird über einen Kaskaden‐Aufbau berichtet, der diese Verfahren kombiniert, um multifunktionale biomolekulare Gerüste in einer modularen Ein‐Topf‐Reaktion aufzubauen.
Markus Staudt, Christian B. M. Poulie, Andreas Löffler, Peter R. Meinig, Riley J. Deutsch‐Williams, Barbara Herrmann, Ralph Weissleder, Hannes Mikula, Jonathan C. T. Carlson, Matthias M. Herth   +9 more
wiley   +1 more source

Dehydroabietylamine derived bistetrazoles from ultrasound-assisted pseudo-seven-component Ugi reactions act as efficient and selective inhibitors of cholinesterases

European Journal of Medicinal Chemistry Reports
The reaction of dehydroabiethylamine (DHA) with isocyanides and formaldehyde produces varying products depending on the conditions employed. In a 4-component Ugi reaction using benzyl isocyanide, paraformaldehyde, and TMS-azide, the anticipated tetrazole
Niels V. Heise, Antonia Schmidt, Jördis-Ann Schüler, René Csuk   +3 more
doaj   +1 more source

Reaction between Indazole and Pd-Bound Isocyanides—A Theoretical Mechanistic Study

Molecules, 2018
The mechanism of the addition of indazole (Ind)—a bifunctional aromatic N,NH-nucleophile—to cyclohexyl isocyanide coordinated to the palladium(II) center in the model complex cis-[PdCl2(CNMe)(CNCy)] (1) to give the corresponding aminocarbene ...
Girolamo Casella, Maurizio Casarin, Vadim Yu. Kukushkin, Maxim L. Kuznetsov   +3 more
doaj   +1 more source

The reaction of arylmethyl isocyanides and arylmethylamines with xanthate esters: a facile and unexpected synthesis of carbamothioates

Beilstein Journal of Organic Chemistry, 2020
An unexpected formation of carbamothioates by a sodium hydride-mediated reaction of arylmethyl isocyanides with xanthate esters in DMF is reported. The products thus obtained were compared with the carbamothioates obtained by the sodium hydride-mediated ...
Narasimhamurthy Rajeev, Toreshettahally R. Swaroop, Ahmad I. Alrawashdeh, Shofiur Rahman, Abdullah Alodhayb, Seegehalli M. Anil, Kuppalli R. Kiran, Chandra, Paris E. Georghiou, Kanchugarakoppal S. Rangappa, Maralinganadoddi P. Sadashiva   +10 more
doaj   +1 more source

Aurophilic Interactions in Cationic Three-Coordinate Gold(I) Bipyridyl/Isocyanide Complex

Crystals, 2022
Gold(I) isocyanide complexes featuring Au···Au interactions attract considerable attention because of their tunable photophysical properties. Although the synthetic exploration of isocyanide gold(I) complexes seems reasonable, their structural diversity ...
Mariya V. Grudova, Alexander S. Novikov, Alexey S. Kubasov, Victor N. Khrustalev, Anatoly A. Kirichuk, Valentine G. Nenajdenko, Alexander G. Tskhovrebov   +6 more
doaj   +1 more source

Electron Donor–Acceptor Complex Catalysis in Synthetic Chemistry

Angewandte Chemie International Edition, EarlyView.
Electron donor–acceptor (EDA) complexes are moving beyond stoichiometric photoactivation toward catalytic platforms for radical generation. Productive EDA catalysis requires coordinated donor–acceptor association, charge‐transfer excitation, radical reactivity, and vcatalyst turnover.
Tristan von Münchow, Andrea Palone, Jonathan Samuel Trimble, Paolo Melchiorre   +3 more
wiley   +1 more source