Results 1 to 10 of about 2,988 (132)
Harnessing unprotected deactivated amines and arylglyoxals in the Ugi reaction for the synthesis of fused complex nitrogen heterocycles [PDF]
Beilstein Journal of Organic ChemistryPiperazines and diazepines are examples of nitrogen heterocycles present in many marketed drugs highlighting their importance in the discovery of novel bioactive compounds.
Javier Gómez-Ayuso +5 more
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Sequential Ugi reaction/base-induced ring closing/IAAC protocol toward triazolobenzodiazepine-fused diketopiperazines and hydantoins [PDF]
Beilstein Journal of Organic Chemistry, 2018 A practical three-step protocol for the assembly of triazolobenzodiazepine-fused diketopiperazines and hydantoins has been developed. The synthesis of these tetracyclic ring systems was initiated by an Ugi reaction, which brought together all necessary ...
Robby Vroemans +7 more
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α-Ketoglutaric acid in Ugi reactions and Ugi/aza-Wittig tandem reactions [PDF]
Beilstein Journal of Organic ChemistryA small library of bis- and tetraamides was synthesized by the Ugi reaction with α-ketoglutaric acid, tert-butyl isocyanide, aromatic aldehydes, and aromatic amines.
Vladyslav O. Honcharov +6 more
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Diastereoselective Ugi reaction of chiral 1,3-aminoalcohols derived from an organocatalytic Mannich reaction [PDF]
Beilstein Journal of Organic Chemistry, 2016 Enantiomerically pure β-aminoalcohols, produced through an organocatalytic Mannich reaction, were subjected to an Ugi multicomponent reaction under classical or Lewis acid-promoted conditions with diastereoselectivities ranging from moderate to good ...
Samantha Caputo +5 more
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N-Hydroxyimide Ugi Reaction toward α-Hydrazino Amides [PDF]
Organic Letters, 2017 Ajay L Chandgude, Alexander Domling
exaly +2 more sources
Ammonia-Promoted One-Pot Tetrazolopiperidinone Synthesis by Ugi Reaction [PDF]
ACS Combinatorial Science, 2017 Justyna Kalinowska-Tłuścik +2 more
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Propargyl Amines: Versatile Building Blocks in Post‐Ugi Transformations
ChemistryOpen, 2023 The Ugi reaction, a multicomponent reaction, allows diversity‐oriented synthesis Its importance is recognized by an exponential increase in the publications utilizing the post‐Ugi transformations as a strategy to build complex molecules via simple and ...
Rinkal B. Bhoraniya, Dr. Sachin G. Modha
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Ugi Four-Component Reactions Using Alternative Reactants
Molecules, 2023 The Ugi four-component reaction (Ugi-4CR) undoubtedly is the most prominent multicomponent reaction (MCRs) that has sparked organic chemists’ interest in the field.
Seyyed Emad Hooshmand, Wei Zhang
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ChemistryOpen, 2023 Straightforward and general Passerini and Ugi procedures have been developed to incorporate four‐membered heterocycles into highly functionalized scaffolds.
Gábor Sztanó +2 more
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Beilstein Journal of Organic Chemistry, 2020 In this report, we introduce a new strategy for controlling the stereochemistry in Ugi adducts. Instead of controlling stereochemistry directly during the Ugi reaction we have attempted to stereodefine the chiral center at the peptidyl position through ...
Yuqing Wang +9 more
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