Results 41 to 50 of about 10,504 (214)

Synthesis of novel glycopeptidomimetics via Nβ-protected- amino alkyl isonitrile based Ugi 4C reaction [PDF]

open access: yes, 2013
The Ugi-4C reaction employing Nβ-protected-amino alkyl isonitrile, amino acid ester, aldehyde, and glycosyl acid has resulted in novel glycosylated peptidomimetics.
Basavaprabhu, H.   +3 more
core   +1 more source

Multicomponent Reaction Based Synthesis of 1-Tetrazolylimidazo[1,5- a]pyridines [PDF]

open access: yes, 2018
A series of unprecedented tetrazole-linked imidazo[1,5- a]pyridines are synthesized from simple and readily available building blocks. The reaction sequence involves an azido-Ugi-deprotection reaction followed by an acetic anhydride-mediated N-acylation ...
Diekstra, Elmar   +5 more
core   +6 more sources

The Catalytic Enantioselective Ugi Four‐Component Reactions [PDF]

open access: yesAngewandte Chemie International Edition, 2018
Finally stereoselective: Enantioselective variations have been developed for many multicomponent reactions; however, it has been missing for the Ugi four-component reaction. This has now changed with the discovery of an efficient catalytic enantioselective variant for the four-component reaction of isocyanides, primary amines, aldehydes or ketones, and
Shabnam Shaabani, Alexander Dömling
openaire   +2 more sources

Diastereoselective Ugi reaction for the synthesis of unnatural amino esters

open access: yesOrbital: The Electronic Journal of Chemistry, 2012
Multicomponent Reactions (MCR) are useful reactions to obtain complex products by the simple mixture of 3 or more reactants. The classic Ugi reaction (4-UCR) involves a mixture of an amine, aldehyde, isocyanide and a carboxylic acid, giving peptoides as ...
Rafael Oliveira Rocha   +4 more
doaj   +1 more source

Medium effects in the production and decay of vector mesons in pion-nucleus reactions [PDF]

open access: yes, 1997
The $\omega$-, $\rho$- and $\phi$-resonance production and their dileptonic decay in $\pi^- A$ reactions at 1.1 - 1.7 GeV/c are calculated within the intranuclear cascade (INC) approach.
Cassing, W.   +2 more
core   +2 more sources

Substituent Effects in Ugi–Smiles Reactions

open access: yesThe Journal of Physical Chemistry A, 2013
In a recent communication, we described the mechanism of the well-known Ugi-type reactions with a model system (J. Org. Chem. 2012, 77, 1361-1366). Herein, focusing on the Ugi-Smiles coupling, we study the effects of each of the four reactants on the energy profile to further explain the experimental results.
Chéron, Nicolas   +4 more
openaire   +3 more sources

DFT Studies on the Stereoselective Three-Component Ugi Reaction

open access: yesOrbital: The Electronic Journal of Chemistry, 2019
Mechanism and stereochemistry of three component Ugi reaction (3C-Ugi) were studied theoretically based on DFT calculations. Structures of reagents, products, intermediates, and transition states were optimized at M062X/6-31+g(d,p) level of theory in gas
Elaheh Sadat Sharifzadeh   +1 more
doaj   +3 more sources

Asymmetric Ugi 3CR on isatin-derived ketimine: synthesis of chiral 3,3-disubstituted 3-aminooxindole derivatives

open access: yesBeilstein Journal of Organic Chemistry, 2014
An efficient Ugi three-component reaction of a preformed chiral ketimine derived from isatin with various isonitrile and acid components has been developed.
Giordano Lesma   +4 more
doaj   +1 more source

The role of the $P_{11}(1710)$ in the $NN{\to}N{\Sigma}K$ reaction

open access: yes, 1998
Using the resonance model, which was successfully applied for the study of the $pp{\to}p{\Lambda}K^+$ reaction, we investigate $NN{\to}N{\Sigma}K$ reactions that should provide cleaner information about resonance excitations and meson exchange ...
Cassing, W.   +3 more
core   +1 more source

One‐Pot Synthesis of a Small Synthetic Ligand for Antibody Purification

open access: yesBiotechnology and Bioengineering, EarlyView.
One‐pot liquid‐phase synthesis of the synthetic ligand B1Al2A2 enables controllable ligand density and efficient capture of IgG and IgY with high recovery and purity, streamlining small‐ligand affinity purification workflows. ABSTRACT The development of synthetic affinity ligands offers a cost‐effective alternative to traditional biological ligands ...
Carolina Mota Natal   +8 more
wiley   +1 more source

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