Results 41 to 50 of about 4,769 (209)
Raising the Diversity of Ugi Reactions Through Selective Alkylations and Allylations of Ugi Adducts [PDF]
Frontiers in Chemistry, 2019 We report here selective Tsuji-Trost type allylation of Ugi adducts using a strategy based on the enhanced nucleophilicity of amide dianions. Ugi adducts derived from aromatic aldehydes were easily allylated at their peptidyl position with allyl acetate in the presence of palladium catalysts.
Alaa Zidan +5 more
openaire +4 more sources
SynOpen, 2018 Biologically attractive azaspiro[4.5]trienones have been prepared via Ugi four-component reaction (Ugi-4CR) followed by bromine-mediated ipso-cyclization.
Saeed Balalaie +5 more
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2014 An efficient Ugi three-component reaction of a preformed chiral ketimine derived from isatin with various isonitrile and acid components has been developed.
Giordano Lesma +4 more
doaj +1 more source
Endoscopic features of cytomegalovirus disease of the upper gastrointestinal tract between transplant and non-transplant patients [PDF]
The Korean Journal of Internal MedicineBackground/Aims Cytomegalovirus (CMV) disease in the upper gastrointestinal (UGI) tract frequently occurs in immunocompromised patients. However, data regarding UGI CMV disease in non-transplant patients compared with those in transplant recipients are ...
Yuri Kim +10 more
doaj +1 more source
Late‐Stage Functionalization of Peptides on the Solid Phase
Angewandte Chemie International Edition, EarlyView.Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner +2 more
wiley +1 more source
, 2016 The Ugi coupling reaction involves the combination of isocyanide (a), aldehyde (b), amine (c) and carboxylic acid (d) components in a single reaction step to give an α-aminoacyl amide product, as exemplified above for the preparation of AZ126.
Darren S. Heeke (3220149) +13 more
core +1 more source
The Ugi reaction in polymer chemistry: syntheses, applications and perspectives
, 2015 The Ugi reaction, one of the most famous multicomponent reactions, has recently been introduced into polymer chemistry as a novel, efficient and useful tool to prepare multifunctional polymers.
Wei, Yen +4 more
core +1 more source
Beilstein Journal of Organic Chemistry, 2019 The synthesis of a novel category of pseudo-peptides via intramolecular Ugi reaction of levulinic acid (4-oxopentanoic acid), aromatic and aliphatic amines, and amino acid-based isocyanides is reported.
Maryam Khalesi +2 more
doaj +1 more source
Molecules, 2022 An efficient method for the synthesis of functionalized peptidomimetics via multicomponent Ugi reaction has been developed. The application of trifluoroethanol (TFE) as a reaction medium provided desired products with good yields.
Parul Sahrawat +6 more
doaj +1 more source
One‐Pot Synthesis of a Small Synthetic Ligand for Antibody Purification
Biotechnology and Bioengineering, EarlyView.One‐pot liquid‐phase synthesis of the synthetic ligand B1Al2A2 enables controllable ligand density and efficient capture of IgG and IgY with high recovery and purity, streamlining small‐ligand affinity purification workflows. ABSTRACT The development of synthetic affinity ligands offers a cost‐effective alternative to traditional biological ligands ...
Carolina Mota Natal +8 more
wiley +1 more source