Results 11 to 20 of about 10,504 (214)
Catalytic Three‐Component Ugi Reaction [PDF]
Angewandte Chemie International Edition, 2008 Perfect atom economy characterizes a novel catalytic three‐component Ugi reaction (see example). Different α‐amino amides are formed in good yields from aldehydes, primary amines, and isocyanides in the presence of phenyl phosphinic acid as the catalyst. The products will be useful for the synthesis of α‐amino acid derivatives and in diversity‐oriented
Pan, S., List, B.
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N-Hydroxyimide Ugi Reaction toward α-Hydrazino Amides. [PDF]
Org Lett, 2017 The Ugi four-component reaction (U-4CR) with N-hydroxyimides as a novel carboxylic acid isostere has been reported. This reaction provides straightforward access to α-hydrazino amides. A broad range of aldehydes, amines, isocyanides and N-hydroxyimides were employed to give products in moderate to high yields.
Chandgude AL, Dömling A.
europepmc +4 more sources
Diastereoselective Ugi reaction of chiral 1,3-aminoalcohols derived from an organocatalytic Mannich reaction [PDF]
Beilstein Journal of Organic Chemistry, 2016 Enantiomerically pure β-aminoalcohols, produced through an organocatalytic Mannich reaction, were subjected to an Ugi multicomponent reaction under classical or Lewis acid-promoted conditions with diastereoselectivities ranging from moderate to good ...
Samantha Caputo +5 more
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Silver(I) triflate-catalyzed post-Ugi synthesis of pyrazolodiazepines [PDF]
Beilstein Journal of Organic ChemistryA silver(I) triflate-catalyzed post-Ugi assembly of novel pyrazolo[1,5-a][1,4]diazepine scaffolds is reported offering high yields (up to 98%) under mild conditions.
Muhammad Hasan +6 more
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Propargyl Amines: Versatile Building Blocks in Post‐Ugi Transformations
ChemistryOpen, 2023 The Ugi reaction, a multicomponent reaction, allows diversity‐oriented synthesis Its importance is recognized by an exponential increase in the publications utilizing the post‐Ugi transformations as a strategy to build complex molecules via simple and ...
Rinkal B. Bhoraniya, Dr. Sachin G. Modha
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ChemistryOpen, 2023 Straightforward and general Passerini and Ugi procedures have been developed to incorporate four‐membered heterocycles into highly functionalized scaffolds.
Gábor Sztanó +2 more
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Open Notebook Science Challenge: Solubilities of Organic Compounds in Organic Solvents [PDF]
, 2010 This book contains the results of the Open Notebook Science Solubility Challenge. All experimental measurements are provided with a link to either the laboratory notebook page where the experiment was carried out or to a literature reference.
Andrew Lang +17 more
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Beilstein Journal of Organic Chemistry, 2020 In this report, we introduce a new strategy for controlling the stereochemistry in Ugi adducts. Instead of controlling stereochemistry directly during the Ugi reaction we have attempted to stereodefine the chiral center at the peptidyl position through ...
Yuqing Wang +9 more
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Molecules, 2023 Herein, advanced intermediates were synthesized through Ugi four-component reactions of isocyanides, aldehydes, masked amino aldehyde, and carboxylic acids, including N-protected amino acids.
Naděžda Cankařová, Viktor Krchňák
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Temperature-Controlled Diastereoselective Doebner/Ugi Tandem Reaction
SynOpen, 2023 Novel peptidomimetics containing a pyrrolone fragment were synthesized by a tandem combination of Doebner and Ugi type multicomponent reactions with controlled diastereoselectivity. This approach represents a convenient synthesis in the temperature range
Yana Sakhno +9 more
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