Results 11 to 20 of about 2,043,921 (203)
N-Hydroxyimide Ugi Reaction toward α-Hydrazino Amides [PDF]
Organic Letters, 2017 The Ugi four-component reaction (U-4CR) with N-hydroxyimides as a novel carboxylic acid isostere has been reported. This reaction provides straightforward access to α-hydrazino amides.
Ajay L Chandgude, Alexander Domling
exaly +5 more sources
Catalytic Three‐Component Ugi Reaction [PDF]
Angewandte Chemie International Edition, 2008 Perfect atom economy characterizes a novel catalytic three‐component Ugi reaction (see example). Different α‐amino amides are formed in good yields from aldehydes, primary amines, and isocyanides in the presence of phenyl phosphinic acid as the catalyst. The products will be useful for the synthesis of α‐amino acid derivatives and in diversity‐oriented
Pan, S., List, B.
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Diastereoselective Ugi reaction for the synthesis of unnatural amino esters
Orbital: The Electronic Journal of Chemistry, 2012 Multicomponent Reactions (MCR) are useful reactions to obtain complex products by the simple mixture of 3 or more reactants. The classic Ugi reaction (4-UCR) involves a mixture of an amine, aldehyde, isocyanide and a carboxylic acid, giving peptoides as ...
Rafael Oliveira Rocha +4 more
doaj +2 more sources
DFT Studies on the Stereoselective Three-Component Ugi Reaction [PDF]
Orbital: The Electronic Journal of Chemistry, 2019 Mechanism and stereochemistry of three component Ugi reaction (3C-Ugi) were studied theoretically based on DFT calculations. Structures of reagents, products, intermediates, and transition states were optimized at M062X/6-31+g(d,p) level of theory in gas
Elaheh Sadat Sharifzadeh +1 more
doaj +4 more sources
Novel postmodifications of the Ugi reaction [PDF]
, 2016 In this thesis several novel postmodifiactions of regular Ugi-4CR products have been examined. Their scope and limitations were tested both by permutating the required functionalities around the Ugi scaffold and by synthesizing compound libraries for successful permutations. The following reactions were examined: 1.
Welsch, Sebastian
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Beilstein Journal of Organic ChemistryA new tandem sequence involving the Ugi reaction and Diels–Alder [4 + 2] cycloaddition based on vinylfuran and 1,3-butadienylfuran derivatives was designed and studied.
Yuriy I. Horak +5 more
doaj +2 more sources
Innovations and Inventions: Why Was the Ugi Reaction Discovered Only 37 Years after the Passerini Reaction? [PDF]
J Org Chem, 2023 This year represents the 100th anniversary of the discovery of the Passerini three-component reaction. The related Ugi four-compound reaction was discovered 37 years after the Passerini reaction.
Dömling A.
europepmc +3 more sources
Ammonia-Promoted One-Pot Tetrazolopiperidinone Synthesis by Ugi Reaction [PDF]
ACS Combinatorial Science, 2017 Justyna Kalinowska-Tłuścik +2 more
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Sulfur-Switch Ugi Reaction for Macrocyclic Disulfide-Bridged Peptidomimetics. [PDF]
Org Lett, 2017 A general strategy is introduced for the efficient synthetic access of disulfide linked artificial macrocycles via a Ugi four-component reaction (U4CR) followed by oxidative cyclization.
Vishwanatha TM +2 more
europepmc +3 more sources
Two-Step Macrocycle Synthesis by Classical Ugi Reaction [PDF]
Journal of Organic Chemistry, 2018 Shabnam Shaabani +2 more
exaly +2 more sources