Results 31 to 40 of about 4,726 (220)

Selectivity in multiple multicomponent reactions: types and synthetic applications

Beilstein Journal of Organic Chemistry, 2019
Multiple multicomponent reactions reach an unparalleled level of connectivity, leading to highly complex adducts. Usually, only one type of transformation involving the same set of reactants takes place.
Ouldouz Ghashghaei, Francesca Seghetti, Rodolfo Lavilla   +2 more
doaj   +1 more source

Physicochemical, biological and application properties of isocyanides, Part 1., Origins, derivation and chemical reactions

, 2023
Isocyanides are the most unusual and unique group in organic chemistry. They possess an unusual valence structure and reactivity. Isocyanides are the only class of stable organic compounds with a formal divalent carbon, which allows them to be the ...
Pobłocki, Kacper, Jacewicz, Dagmara, Pawlak, Marta, Drzeżdżon, Joanna   +3 more
core   +1 more source

Sulfonyl isocyanides RSO2NC

, 2017
Flash vacuum pyrolysis (FVP) of 5-azido-1-aryltetrazoles results in triple N2 elimination and formation of aryl isocyanides RNC, which rearrange in part to aroylnitriles RCN under the reaction conditions.
Horst, Briehl, Curt, Wentrup
core   +1 more source

Biosynthetic Routes to Natural Isocyanides

, 2020
International audienceAs intriguing as it may appear, natural products bearing an isocyanide function are well known in different kingdoms of living organisms.
Evanno, Laurent, Poupon, Erwan, Laurent Evanno, Erwan Poupon, Xinming Zhang, Zhang, Xinming   +5 more
core   +1 more source

Leuckart-Wallach Approach to Sugar Isocyanides and Its IMCRs [PDF]

, 2015
We utilize our recently introduced Leuckart-Wallach approach to synthesize anomeric sugar isocyanides in good overall yields and two steps. Moreover, we show the general usage of these isocyanides in isocyanide-based multicomponent reactions (IMCRs) to ...
Neochoritis, Dinos, Zhang, Ji, Dömling, Alex   +2 more
core   +1 more source

Exploiting the Nucleophilicity of the Nitrogen Atom of Imidazoles: One-Pot Three-Component Synthesis of Imidazo-Pyrazines

Molecules, 2019
A novel one-pot multicomponent reaction to synthesize substituted imidazopyrazines is described. In brief, 1H-(imidazol-5-yl)-N-substituted methanamines react with aldehydes and isocyanides in methanol at room temperature to give imidazopyrazine ...
Ubaldina Galli, Rejdia Hysenlika, Fiorella Meneghetti, Erika Del Grosso, Sveva Pelliccia, Ettore Novellino, Mariateresa Giustiniano, Gian Cesare Tron   +7 more
doaj   +1 more source

The Isocyanide Complexes cis-[MCl₂(CNC₆H₄-4-X)₂] (M = Pd, Pt; X = Cl, Br) as Tectons in Crystal Engineering Involving Halogen Bonds

Crystals, 2021
The isocyanide complexes cis-[MCl2(CNC6H4-4-X)2] (M = Pd; X = Cl, Br; M = Pt; X = Br) form isomorphous crystal structures exhibiting the Cl/Br and Pd/Pt exchanges featuring 1D chains upon crystallisation.
Maria V. Kashina, Daniil M. Ivanov, Mikhail A. Kinzhalov   +2 more
doaj   +1 more source

A novel three-component reaction between isocyanides, alcohols or thiols and elemental sulfur: a mild, catalyst-free approach towards O-thiocarbamates and dithiocarbamates

Beilstein Journal of Organic Chemistry, 2019
A new multicomponent reaction has been developed between isocyanides, sulfur and alcohols or thiols under mild reaction conditions to afford O-thiocarbamates and dithiocarbamates in moderate to good yields.
András György Németh, György Miklós Keserű, Péter Ábrányi-Balogh   +2 more
doaj   +1 more source

Reaction between Indazole and Pd-Bound Isocyanides—A Theoretical Mechanistic Study

Molecules, 2018
The mechanism of the addition of indazole (Ind)—a bifunctional aromatic N,NH-nucleophile—to cyclohexyl isocyanide coordinated to the palladium(II) center in the model complex cis-[PdCl2(CNMe)(CNCy)] (1) to give the corresponding aminocarbene ...
Girolamo Casella, Maurizio Casarin, Vadim Yu. Kukushkin, Maxim L. Kuznetsov   +3 more
doaj   +1 more source

The reaction of arylmethyl isocyanides and arylmethylamines with xanthate esters: a facile and unexpected synthesis of carbamothioates

Beilstein Journal of Organic Chemistry, 2020
An unexpected formation of carbamothioates by a sodium hydride-mediated reaction of arylmethyl isocyanides with xanthate esters in DMF is reported. The products thus obtained were compared with the carbamothioates obtained by the sodium hydride-mediated ...
Narasimhamurthy Rajeev, Toreshettahally R. Swaroop, Ahmad I. Alrawashdeh, Shofiur Rahman, Abdullah Alodhayb, Seegehalli M. Anil, Kuppalli R. Kiran, Chandra, Paris E. Georghiou, Kanchugarakoppal S. Rangappa, Maralinganadoddi P. Sadashiva   +10 more
doaj   +1 more source