Results 11 to 20 of about 8,383 (210)

Sequential Homo- and Hetero-Coupling of Isocyanide and Carbon Monoxide Mediated by Acyclic Imino(silyl)Silylene. [PDF]

Angew Chem Int Ed Engl
We demonstrate the sequential reactions between an imino(hypersilyl)silylene and aryl isocyanide or carbon monoxide as a molecular‐level model of the Fischer–Tropsch process, providing systematic and detailed insight into C–C bond formation during the homologation of C1 building blocks.
Zhu H, Kostenko A, Liu X, Inoue S.
europepmc   +3 more sources

Copper- and Silver-Catalyzed Reactions of Active Methylene Isocyanides: Facile Access to Highly Substituted Five- and Six-Membered Heterocycles. [PDF]

Chemistry
This review summarizes recent advances in copper‐ and silver‐catalyzed reactions of active methylene isocyanides for the synthesis of highly substituted five‐ and six‐membered heterocycles. Emphasis is placed on [3+n] cycloadditions, annulations, and asymmetric strategies, highlighting current limitations and future opportunities in heterocycle ...
George J, Oh K.
europepmc   +2 more sources

Efficient Isocyanide-less Isocyanide-Based Multicomponent Reactions [PDF]

Organic Letters, 2015
Isocyanides are the "Jekyll and Hyde" of organic chemistry allowing for extremely interesting transformations that are not only extremely odorous but also noxious. Therefore, an isocyanide-less isocyanide-based multicomponent reaction (IMCR) has been developed, and this protocol is expected to replace many of the old procedures in the future not only ...
Neochoritis, Constantinos G.; Stotani, Silvia; Mishra, Bhupendra; Domling, Alexander   +4 more
openaire   +3 more sources

2‐Nitrobenzyl Isocyanide as a Universal Convertible Isocyanide [PDF]

Asian Journal of Organic Chemistry, 2017
Abstract2‐Nitrobenzyl isocyanide is reported as a universal convertible isocyanide with extensive applicability in both Ugi four‐component reaction (Ugi‐4CR) and Ugi‐tetrazole reaction. The cleavage of this isocyanide from 17 examples in both acidic and basic conditions is presented.
Chandgude, Ajay L.; Li, Jingyao; Domling, Alexander   +3 more
openaire   +3 more sources

The isocyanide SN2 reaction

Nature Communications, 2023
Abstract The S N 2 nucleophilic substitution reaction is a vital organic transformation used for drug and natural product synthesis. Nucleophiles like cyanide, oxygen, nitrogen, sulfur, or phosphorous replace halogens or sulfonyl esters, forming new bonds.
Patil, Pravin, Zheng, Qiang, Kurpiewska, Katarzyna, Dömling, Alexander   +3 more
openaire   +4 more sources

Multicomponent Reactions of Isocyanides for the Preparation of Low Molecular Weight Gelators: Preliminary Studies

Chemistry Proceedings, 2021
Low molecular weight gelators, LMWGs, are small molecules that can self-associate in organic solvents or in water to form fibrous supramolecular architectures and three-dimensional networks that present important applications in several fields.
José L. Ramiro, Carlos F. Marcos, Ana G. Neo   +2 more
doaj   +1 more source

Conductance of a single molecule anchored by an isocyanide substituent to gold electrodes [PDF]

, 2006
The effect of anchoring group on the electrical conductance of a single molecule bridging two Au electrodes was studied using di-substituted (isocyanide (CN-), thiol (S-) or cyanide (NC-)) benzene.
Cunningham I. D., Kei Murakoshi, Kenji Hara, Manabu Kiguchi, Masaya Sawamura, Shinichi Miura   +5 more
core   +2 more sources

Three-Component Reaction of 3-Arylidene-3H-Indolium Salts, Isocyanides, and Alcohols

Frontiers in Chemistry, 2019
A novel isocyanide-based multicomponent synthesis of alkyl aryl(indol-3-yl)acetimidates has been established. Starting from aryl(indol-3-yl)methylium tetrafluoroborates, aromatic isocyanides and alcohols, the imidates were obtained in moderate to very ...
Nikita E. Golantsov, Hung M. Nguyen, Alexandra S. Golubenkova, Alexey V. Varlamov, Erik V. Van der Eycken, Erik V. Van der Eycken, Leonid G. Voskressensky   +6 more
doaj   +1 more source

Semisynthesis of 6β-Acetoxyvouacapane Derivatives via the Ugi-Azide Multicomponent Reaction

Chemistry Proceedings, 2022
A semisynthesis of 6β-acetoxyvouacapane-1,5-disusbtituted tetrazoles derivatives from the leaves of Caesalpinia platyloba by using the Ugi-azide multicomponent reaction as a key step reaction is described. To our knowledge, this is the first report where
Gabriela Servín-García, Luis Chacón-García, Joaquín González-Marrero, Mariana Macías-Alonso, Mario A. Gómez-Hurtado, Gabriela Rodríguez-García, Rosa E. del Río, Carlos J. Cortés-García   +7 more
doaj   +1 more source

5,6-Dihydro-2H-pyran-3(4H)-on als Baustein zur Synthese pyrananellierter Heterocyclen [PDF]

, 1984
Während 5,6-Dihydro-2H-pyran-3(4H)-on (3) sich mit ortho-substituierten Phenylcarbonylverbindungen nur in Einzelfällen regioselektiv zu pyrananellierten Heterocyclen umsetzt - z. B.
Eiden, Fritz, Wanner, Klaus Th.
core   +1 more source