Results 21 to 30 of about 5,182 (207)

Three-Component Reaction of 3-Arylidene-3H-Indolium Salts, Isocyanides, and Alcohols

Frontiers in Chemistry, 2019
A novel isocyanide-based multicomponent synthesis of alkyl aryl(indol-3-yl)acetimidates has been established. Starting from aryl(indol-3-yl)methylium tetrafluoroborates, aromatic isocyanides and alcohols, the imidates were obtained in moderate to very ...
Nikita E. Golantsov, Hung M. Nguyen, Alexandra S. Golubenkova, Alexey V. Varlamov, Erik V. Van der Eycken, Erik V. Van der Eycken, Leonid G. Voskressensky   +6 more
doaj   +1 more source

Pyrrolidinodiones in Enol-Ugi, Enol-Passerini, and Anomalous Enol-Passerini Condensations

Proceedings, 2019
In continuation of our recent research on the development of novel multicomponent reactions with isocyanides, we have used, for the first time, enols as the acid components in Ugi- and Passerini-type reactions. Thus, electron-poor pyrrolidinodiones react
Ana G. Neo, Carlos F. Marcos
doaj   +1 more source

Multicomponent Reactions of Isocyanides for the Preparation of Low Molecular Weight Gelators: Preliminary Studies

Chemistry Proceedings, 2021
Low molecular weight gelators, LMWGs, are small molecules that can self-associate in organic solvents or in water to form fibrous supramolecular architectures and three-dimensional networks that present important applications in several fields.
José L. Ramiro, Carlos F. Marcos, Ana G. Neo   +2 more
doaj   +1 more source

Cyclization of Activated Methylene Isocyanides with Methyl N(N),N′-Di(tri)substituted Carbamimidothioate: A Novel Entry for the Synthesis of N,1-Aryl-4-tosyl/ethoxycarbonyl-1H-imidazol-5-amines

SynOpen, 2019
Base-induced cyclization of active methylene isocyanides with carbamimidothioates for the synthesis of N,1-aryl-4-tosyl/ethylcarboxy-1H-imidazol-5-amines is reported.
Dukanya Dukanya, Toreshettahally R. Swaroop, Shobith Rangappa, Kanchugarakoppal S. Rangappa, Basappa Basappa   +4 more
doaj   +1 more source

Semisynthesis of 6β-Acetoxyvouacapane Derivatives via the Ugi-Azide Multicomponent Reaction

Chemistry Proceedings, 2022
A semisynthesis of 6β-acetoxyvouacapane-1,5-disusbtituted tetrazoles derivatives from the leaves of Caesalpinia platyloba by using the Ugi-azide multicomponent reaction as a key step reaction is described. To our knowledge, this is the first report where
Gabriela Servín-García, Luis Chacón-García, Joaquín González-Marrero, Mariana Macías-Alonso, Mario A. Gómez-Hurtado, Gabriela Rodríguez-García, Rosa E. del Río, Carlos J. Cortés-García   +7 more
doaj   +1 more source

Recent Advances in Palladium-Catalyzed Isocyanide Insertions

Molecules, 2020
Isocyanides have long been known as versatile chemical reagents in organic synthesis. Their ambivalent nature also allows them to function as a CO-substitute in palladium-catalyzed cross couplings.
Jurriën W. Collet, Thomas R. Roose, Bram Weijers, Bert U. W. Maes, Eelco Ruijter, Romano V. A. Orru   +5 more
doaj   +1 more source

Physicochemical, biological and application properties of isocyanides, Part 1., Origins, derivation and chemical reactions [PDF]

, 2023
Isocyanides are the most unusual and unique group in organic chemistry. They possess an unusual valence structure and reactivity. Isocyanides are the only class of stable organic compounds with a formal divalent carbon, which allows them to be the ...
Pobłocki, Kacper, Jacewicz, Dagmara, Pawlak, Marta, Drzeżdżon, Joanna   +3 more
core   +1 more source

Xanthate Based Radical Cascade Toward Multicomponent Formation of Pyrrolopyrimidines

Molecules, 2011
A short sequential synthesis of pyrrolidino- pyridines and pyrimidines illustrates the potential of combining Ugi-Smiles couplings with radical tin-free processes.
Patil Pravin, Laurence Grimaud, Laurent El Kaïm   +2 more
doaj   +1 more source

Selectivity in multiple multicomponent reactions: types and synthetic applications

Beilstein Journal of Organic Chemistry, 2019
Multiple multicomponent reactions reach an unparalleled level of connectivity, leading to highly complex adducts. Usually, only one type of transformation involving the same set of reactants takes place.
Ouldouz Ghashghaei, Francesca Seghetti, Rodolfo Lavilla   +2 more
doaj   +1 more source

Passerini and Ugi Reactions Involving Kinetically Unstable Isocyanides

, 2021
International audienceKinetically unstable isocyanides as vinyl, allenyl and propargyl isocyanides react in Passerini and Ugi reactions faster than they decompose and lead to functionalized alpha-acyloxy amides and alpha-amino amides, respectively, which
Yann Trolez, Guillemin, Jean-Claude, Trolez, Yann, Alexandre Quelhas, Roisnel, Thierry, Thierry Roisnel, Jean‐Claude Guillemin, Quelhas, Alexandre, Gazzeh, Houda, Houda Gazzeh   +9 more
core   +1 more source