Results 21 to 30 of about 4,726 (220)
SynOpen, 2019 Base-induced cyclization of active methylene isocyanides with carbamimidothioates for the synthesis of N,1-aryl-4-tosyl/ethylcarboxy-1H-imidazol-5-amines is reported.
Dukanya Dukanya +4 more
doaj +1 more source
Recent Advances in Palladium-Catalyzed Isocyanide Insertions
Molecules, 2020 Isocyanides have long been known as versatile chemical reagents in organic synthesis. Their ambivalent nature also allows them to function as a CO-substitute in palladium-catalyzed cross couplings.
Jurriën W. Collet +5 more
doaj +1 more source
Molecules, 2023 α-Ketoamide moieties, as privileged units, may represent a valuable option to develop compounds with favorable biological activities, such as low toxicity, promising PK and drug-like properties.
Jia Xu +6 more
doaj +1 more source
Amide-Stabilized Enols in the Enol-Ugi Reaction: A Five-Component Synthesis of Triamides
Chemistry Proceedings, 2021 In continuation with our research in the use of enols in multicomponent reactions with isocyanides (IMCR), for the first time we have used amide-stabilized enols as the acid component in enol-Ugi reactions.
Ana G. Neo +3 more
doaj +1 more source
In-water synthesis of isocyanides under micellar conditions [PDF]
, 2022 An in-water dehydration of N-formamides to afford isocyanides using micellar conditions at room temperature is reported. This method allows for the preparation of aliphatic isocyanides in an environmental friendly manner.
Russo C. +4 more
core +1 more source
Anodic oxidation of aminotetrazoles: a mild and safe route to Isocyanides [PDF]
, 2021 A new electrochemical method for the preparation of isocyanides from easily accessible aminotetrazole derivatives has been developed, which tolerates an unprecedented range of functional groups. The use of chemical, rather than electrochemical, oxidation
Goodall, Iain C. A. +10 more
core +2 more sources
On the reaction of diphenylketene with isocyanides
Organic & Biomolecular Chemistry, 2005 The products obtained from the reaction of diphenylketene with a variety of isocyanides are shown to depend heavily on the concentration of diphenylketene; a high concentration results in the precedented dioxolane derivatives, at much lower concentrations the reactions follow an alternative course and polycyclic beta-lactams are generated by a cascade ...
Robertson, J, Bell, S, Krivokapic, A
openaire +3 more sources
Passerini and Ugi Reactions Involving Kinetically Unstable Isocyanides
, 2021 International audienceKinetically unstable isocyanides as vinyl, allenyl and propargyl isocyanides react in Passerini and Ugi reactions faster than they decompose and lead to functionalized alpha-acyloxy amides and alpha-amino amides, respectively, which
Yann Trolez +9 more
core +1 more source
Xanthate Based Radical Cascade Toward Multicomponent Formation of Pyrrolopyrimidines
Molecules, 2011 A short sequential synthesis of pyrrolidino- pyridines and pyrimidines illustrates the potential of combining Ugi-Smiles couplings with radical tin-free processes.
Patil Pravin +2 more
doaj +1 more source
, 2020 Despite the isolation of hundreds of bioactive isocyanides from terrestrial fungi and bacteria as well as marine organisms, the isocyanide functionality has so far received little attention from a medicinal chemistry standpoint. The widespread tenet that
Purghè, Beatrice +4 more
core +2 more sources