Results 61 to 70 of about 1,650 (181)

Late‐Stage Functionalization of Peptides on the Solid Phase

Angewandte Chemie International Edition, Volume 65, Issue 31, 27 July 2026.
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source

An Ugi–Joullié Platform for Medicinally Relevant 1,4‐Dihydrobenzothiazines

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
A series of benzothiazine derivatives was efficiently synthesized via an UJ‐2CR of a preformed imine and diverse isocyanides. The method features mild, room‐temperature conditions, broad functional‐group tolerance, and scalability, enabling rapid access to a chemically diverse library of 19 adducts with potential for further medicinal chemistry ...
Xiaofang Lei, Christina Tomza, Maria‐Aikaterini Giannakaki, Maria Gkountouva, Ioannis Olbasalis, Rafaela Maria Giappa, Constantinos C. Stoumpos, Christos Kontogiorgis, Alexander Dömling, Constantinos G. Neochoritis   +9 more
wiley   +1 more source

2D Rhodium‐Isocyanide Frameworks

Advanced Materials
Abstract 2D metal‐organic frameworks (2D MOFs) are emerging organic van der Waals materials with great potential in various applications owing to their structural diversity, and tunable optoelectronic properties.
Senhe Huang, Pu Yan, Zhiya Han, Hongyu Wu, Youcheng Wang, Jichao Zhang, Lei Yuan, Shuai Fu, Guanzhao Wen, Jinhui Zhu, Mischa Bonn, Hai I. Wang, Kecheng Cao, Xiaodong Zhuang   +13 more
openaire   +3 more sources

Design, Synthesis, and Photophysical Studies of Functionalized Polyaromatic Isonitriles as Visible Light Photoredox Catalysts

European Journal of Organic Chemistry, Volume 29, Issue 25, 4 July 2026.
A new series of structurally rich polyaromatic isonitriles is presented as photoredox catalysts. Their photophysical properties are investigated by UV–Vis absorption and fluorescence measurements, combined with experimental and theoretical studies to evaluate both ground‐ and excited‐state redox properties.
Cristina Martini, Camilla Russo, Jussara Amato, Carmine Volpe, Francesca Brunelli, Laurence Grimaud, Maxime R. Vitale, Greta Donati, Andrea Basso, Mariateresa Giustiniano   +9 more
wiley   +1 more source

Recent Advances in Benzannulation Approaches to Aromatic Frameworks

Chemistry – An Asian Journal, Volume 21, Issue 13, 14 July 2026.
This review summarizes benzannulation strategies reported over the past 5 years, highlighting recent advances that enable efficient access to structurally diverse and highly substituted arenes through both transition‐metal‐catalyzed and metal‐free approaches.
Heeeun Kim, Yonghoon Kwon
wiley   +1 more source

Droplet microfluidics: Enabling the tailored fabrication of hydrogel particles

Droplet, Volume 5, Issue 3, July 2026.
Droplet microfluidics enables precise, versatile fabrication of hydrogel particles with controlled size, composition, and structure. This review summarizes fundamental principles, engineering strategies, and emerging applications, providing a framework for advancing microfluidic hydrogel technologies.
Zhongqiao Gan, Xu Hou
wiley   +1 more source

Poly(O‐Propargyl‐N‐Amino Carbamate), a Reactive Polymer to Underpin Biomedical Applications of Poly(acetylene)s

Macromolecular Rapid Communications, Volume 47, Issue 14, 20 July 2026.
We report here a new methodology to prepare functional poly(acetylene)s under aqueous conditions. This methodology is underpinned by poly(O‐propargyl‐N‐amino carbamate) (P1), a reactive poly(acetylene) carrying acyl hydrazines. Thus, P1 reacts with aldehydes to give functional poly(acetylene)s, including cationic, hydrophobic, and sugar‐loaded poly ...
Tom Leigh, Greta Bellio, Daniel Crisan, Amit Deb, Alba Ramil‐Bouzas, Andrey Romanyuk, Ivan Torreiro‐Leon, Ana Rey‐Rico, Paco Fernandez‐Trillo   +8 more
wiley   +1 more source

Microwave-Assisted Synthesis of Novel Functionalized Ketenimines and Azadienes via a Solvent-Free Reaction of Isatoic Anhydride, Alkyl-Isocyanides and Dialkyl Acetylenedicarboxylates [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2019
Ketenimines and azadienes are transient intermediates in organic chemistry especially in elimination-addition processes and in the formation of heterocyclic systems.
Samira Arab-Salmanabadi
doaj  

Passerini Reactions on Biocatalytically Derived Chiral Azetidines

Molecules, 2016
The purpose of this study was to explore a series of Passerini reactions on a biocatalytically derived enantiopure azetidine-2-carboxyaldehyde in order to obtain, in a diastereoselective manner, polyfunctionalised derivatives having the potential to be ...
Lisa Moni, Luca Banfi, Andrea Basso, Andrea Bozzano, Martina Spallarossa, Ludger Wessjohann, Renata Riva   +6 more
doaj   +1 more source

Divergent Synthesis of Novel Five-Membered Heterocyclic Compounds by Base-Mediated Rearrangement of Acrylamides Derived from a Novel Isocyanide-Based Multicomponent Reaction

Molecules, 2011
We have recently reported a novel multicomponent reaction between arylacetic acids and isocyanides, affording α-acyloxyacrylamides through an unusual mechanism.
Renata Riva, Andrea Basso, Luca Banfi
doaj   +1 more source