Results 71 to 80 of about 1,650 (181)

Multicomponent Reaction-Based Trimethoprim Analogues as Potential Antibiotics for Resistant Bacteria

Proceedings, 2019
Aminoimidazoles are relevant scaffolds in medicinal. [...]
Rodolfo Lavilla, Marina Pedrola, Ouldouz Ghashghaei, Eda Jardas, Ferran Jardí, Marta Jorba, Miquel Viñas   +6 more
doaj   +1 more source

Exploitation of the Ugi 5-Center-4-Component Reaction (U-5C-4CR) for the Generation of Diverse Libraries of Polycyclic (Spiro)Compounds

Frontiers in Chemistry, 2018
An Ugi multicomponent reaction with chiral cyclic amino acids, benzyl isocyanide and cyclic ketones (or acetone) has been exploited as key step for the generation of peptidomimetics.
Lisa Moni, Fabio De Moliner, Silvia Garbarino, Jörn Saupe, Christian Mang, Andrea Basso   +5 more
doaj   +1 more source

Studies on the interaction of isocyanides with imines: reaction scope and mechanistic variations

Beilstein Journal of Organic Chemistry, 2014
The interaction of imines with isocyanides has been studied. The main product results from a sequential process involving the attack of two units of isocyanide, under Lewis acid catalysis, upon the carbon–nitrogen double bond of the imine to form the 4 ...
Ouldouz Ghashghaei, Consiglia Annamaria Manna, Esther Vicente-García, Marc Revés, Rodolfo Lavilla   +4 more
doaj   +1 more source

The Groebke–Blackburn–Bienaymé reaction in its maturity: innovation and improvements since its 21st birthday (2019–2023)

Beilstein Journal of Organic Chemistry
The Groebke–Blackburn–Bienaymé (GBB) three-component reaction, discovered in 1998, is a very efficient strategy to assemble imidazo[1,2-a]-heterocycles starting from amidines, aldehydes and isocyanides.
Cristina Martini, Muhammad Idham Darussalam Mardjan, Andrea Basso   +2 more
doaj   +1 more source

Crystal structure and Hirshfeld surface analysis of chlorido(2,6-dimethylphenyl isocyanide)[N′-(2,6-dimethylphenyl)-N-(pyridin-2-yl)carbamimidoyl]platinum(II)

Acta Crystallographica Section E: Crystallographic Communications
In the title compound, [Pt(C14H14N3)Cl(C9H9N)], the platinum atom has a square-planar geometry. In the crystal, dimers with R22(8) motifs are formed by pairs of N—H...N hydrogen bonds.
Olga V. Repina, Elena Yu. Nevskaya, Ilya S. Kritchenkov, Victor N. Khrustalev, Alexander S. Novikov, Alexander G. Tskhovrebov, Namiq Q. Shikhaliyev, Aytan A. Niyazova, Mehmet Akkurt, Ajaya Bhattarai   +9 more
doaj   +1 more source

Development and mechanistic studies of calcium–BINOL phosphate-catalyzed hydrocyanation of hydrazones

Beilstein Journal of Organic Chemistry
Asymmetric hydrocyanation of hydrazones, catalyzed by a calcium–BINOL phosphate complex, has been studied for the first time both experimentally and computationally with DFT methods.
Carola Tortora, Christian A. Fischer, Sascha Kohlbauer, Alexandru Zamfir, Gerd M. Ballmann, Jürgen Pahl, Sjoerd Harder, Svetlana B. Tsogoeva   +7 more
doaj   +1 more source

Corrigendum: Exploitation of the Ugi 5-Center-4-Component Reaction (U-5C-4CR) for the Generation of Diverse Libraries of Polycyclic (Spiro)Compounds

Frontiers in Chemistry, 2018
Lisa Moni, Fabio De Moliner, Silvia Garbarino, Jörn Saupe, Christian Mang, Andrea Basso   +5 more
doaj   +1 more source

Non-innocent behaviour of aromatic isocyanides under visible light: a pathway to thioformimidates and dehydroalanine. [PDF]

Chem Sci
Wu M, Hanssens J, Russo C, Walia R, Giustiniano M, Troian-Gautier L, Saya JM, Orru R, Ranjan P.   +8 more
europepmc   +1 more source

Copper- and Silver-Catalyzed Reactions of Active Methylene Isocyanides: Facile Access to Highly Substituted Five- and Six-Membered Heterocycles. [PDF]

Chemistry
George J, Oh K.
europepmc   +1 more source

Stepwise B[triple bond, length as m-dash]N bond cleavage by isocyanides: access to the 3-azaborole structural motif. [PDF]

Chem Sci
Xiang L, Kwan KH, Jing Y, Wang J, Matler A, Chen X, Lin Z, Ye Q.   +7 more
europepmc   +1 more source