Results 81 to 90 of about 5,434 (218)

Biosynthetic Pathways and Regulation of Antibacterial Compounds From Endophytic Fungi: From Chemistry to Genomics and Biotechnology

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
Endophytic fungi encode abundant cryptic biosynthetic gene clusters that remain largely silent under conventional cultivation. This review highlights how genome mining, multi‐omics, and cluster activation strategies bridge the BGC‐to‐metabolite gap, enabling the discovery of structurally diverse antibacterial natural products with activity against ...
Farkhod Eshboev, Abubakar Siddiq Salihu, Lobar Khayrullaeva, Doniyor Khamdamov, Alex X. Gao, Kamila Mardieva, Wan Mohd Nuzul Hakimi Wan Salleh, Shakhnoz Azimova, Karl W. K. Tsim   +8 more
wiley   +1 more source

Leuckart-Wallach Approach to Sugar Isocyanides and Its IMCRs [PDF]

, 2015
We utilize our recently introduced Leuckart-Wallach approach to synthesize anomeric sugar isocyanides in good overall yields and two steps. Moreover, we show the general usage of these isocyanides in isocyanide-based multicomponent reactions (IMCRs) to ...
Neochoritis, Dinos, Zhang, Ji, Dömling, Alex   +2 more
core   +1 more source

Reactions of Isocyanides with Metal Carbyne Complexes: Isolation and Characterization of Metallacyclopropenimine Intermediates

, 2017
η2-Iminoketenyl species have often been postulated as the intermediates in nucleophile-induced carbyne-isocyanide C-C coupling processes. However, such species are elusive.
Liu, Gang, Ming Luo, Xia, Haiping, Luo, Ming, Haiping Xia, Zhang, Hong, Gang Liu, Yang, Yuhui, Yuhui Hua, Zhenyang Lin, Lipeng Long, Hua, Yuhui, Hong Zhang, Lin, Zhenyang, Yuhui Yang, Long, Lipeng   +15 more
core   +2 more sources

A straightforward preparation of chiral 5-(aminomethyl)oxazole derivatives from α-amino esters and α-lithiated isocyanides [PDF]

An efficient and general preparation of several chiral N-protected 5- (aminomethyl)oxazoles has been accomplished by treatment of N-protected α- amino esters with α-lithiated isocyanides, obtained by metalation of methyl and benzyl isocyanides with BuLi ...
Fujii, Tozo, Kubo, Hiroyuki, Seto, Shigeki, Ishibashi, Hiroyuki, Ohba, Masashi   +4 more
core   +2 more sources

Oxazole Synthesis from Isocyanides

, 2012
International audienceA new synthetic path toward oxazoles starting from isocyanides is presented. This two-step oxazole preparation involves a bromination-cyclization followed by a Suzuki cross-coupling.
Patil, Pravin, Grimaud, Laurence, El Kaim, Laurent   +2 more
core   +1 more source

Multicomponent reaction between (Z)-chloroximes, isocyanides and NH-heterocyclic rings

, 2021
An operationally simple multicomponent reaction utilizing (Z)-chloroximes, isocyanides and NH-heterocyclic rings (imidazole, benzimidazole, triazole, benzotriazole and tetrazole) affords a hitherto unknown class of compounds which cannot be obtained via ...
Russo C., Giustiniano M., Galli U., Tron G. C., Brunelli F., Francesca Brunelli, Mariateresa Giustiniano, Gian Cesare Tron, Ubaldina Galli, Camilla Russo   +9 more
core   +1 more source

Cyclopropylamine‐Derived Distonic Iminium Radicals: Photoinduced Strategies in Chemo‐ and Stereo‐Selective Synthesis

Chemistry – A European Journal, Volume 32, Issue 39, 22 October 2026.
Cyclopropylamines have emerged as powerful photocatalytic building blocks. Upon light‐induced single‐electron oxidation, they undergo strain‐release ring opening to generate distonic iminium radicals that enable diverse transformations, including ring‐opening functionalization, formal [3 + 2] cycloadditions, radical cascades, and asymmetric bond ...
Maria Chiara Cabua, Alberto Luridiana, Francesco Secci, Emanuele Cocco   +3 more
wiley   +1 more source

Hybrid Macrocyclic Peptides — Synthetic Strategies to Diversify and Cyclize Peptide Libraries in Phage Display Selections

Chemistry – A European Journal, Volume 32, Issue 39, 22 October 2026.
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley   +1 more source

Microwave-Assisted Synthesis of Novel Functionalized Ketenimines and Azadienes via a Solvent-Free Reaction of Isatoic Anhydride, Alkyl-Isocyanides and Dialkyl Acetylenedicarboxylates [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2019
Ketenimines and azadienes are transient intermediates in organic chemistry especially in elimination-addition processes and in the formation of heterocyclic systems.
Samira Arab-Salmanabadi
doaj  

Counterion Effects in Decatungstate Photocatalysis

European Journal of Organic Chemistry, Volume 29, Issue 39, 22 October 2026.
Decatungstate photocatalysis is often discussed from an anion‐centered perspective, treating the counterion as a passive charge‐balancing species. This review highlights that counterion identity can instead profoundly influence catalyst solubility, ion pairing, aggregation, stability, substrate accessibility, and catalytic performance.
Florence Babawale, Burkhard König, Indrajit Ghosh   +2 more
wiley   +1 more source