Results 101 to 110 of about 8,425 (228)

Multicomponent Reactions Upon the Known Drug Trimethoprim as a Source of Novel Antimicrobial Agents

Frontiers in Chemistry, 2019
Novel antibiotic compounds have been prepared through a selective multicomponent reaction upon the known drug Trimethoprim. The Groebke-Blackburn-Bienaymé reaction involving this α-aminoazine, with a range of aldehydes and isocyanides afforded the ...
Marina Pedrola, Marta Jorba, Marta Jorba, Eda Jardas, Ferran Jardi, Ouldouz Ghashghaei, Miguel Viñas, Miguel Viñas, Rodolfo Lavilla   +8 more
doaj   +1 more source

Rh(III)‐Catalyzed [4+2] Annulation of Imidazoles With α‐Diazocarbonyl Compounds: Direct Access to π‐Conjugated Imidazole‐Fused Isoquinolinone

European Journal of Organic Chemistry, EarlyView.
A Rh(III)‐catalyzed [4 + 2] annulation of 2‐aryl imidazoles/benzimidazoles with α‐diazocarbonyl compounds is developed for the synthesis of π‐conjugated imidazo/benzimidazo[2,1‐a]isoquinolinones systems. Mechanistic studies and control experiment reveal that the reaction proceeds via imidazole‐directed ortho C(sp2)–H activation, followed by carbene C–H
Ganesh P. Pawar, Duc Huy Le, Li Ching Shen, Sheng‐Cih Huang, Chung‐Ming Sun   +4 more
wiley   +1 more source

Poly(O‐Propargyl‐N‐Amino Carbamate), a Reactive Polymer to Underpin Biomedical Applications of Poly(acetylene)s

Macromolecular Rapid Communications, EarlyView.
We report here a new methodology to prepare functional poly(acetylene)s under aqueous conditions. This methodology is underpinned by poly(O‐propargyl‐N‐amino carbamate) (P1), a reactive poly(acetylene) carrying acyl hydrazines. Thus, P1 reacts with aldehydes to give functional poly(acetylene)s, including cationic, hydrophobic, and sugar‐loaded poly ...
Tom Leigh, Greta Bellio, Daniel Crisan, Amit Deb, Alba Ramil‐Bouzas, Andrey Romanyuk, Ivan Torreiro‐Leon, Ana Rey‐Rico, Paco Fernandez‐Trillo   +8 more
wiley   +1 more source

Multicomponent reactions of methyl substituted all-cis tetrafluorocyclohexane aldehydes [PDF]

, 2016
The authors thank the EPSRC for supporting this work and DO’H is grateful for a Royal Society Wolfson Research Merit Award.This paper reports the preparation of methyl substituted all-cis tetrafluorocyclohexanes prepared from a Birch reduction of benzoic
Al-Maharik, Nawaf, Bykova, Tanya, O'Hagan, David, Slawin, Alexandra Martha Zoya   +3 more
core   +1 more source

On Phosphatitanacycles

Zeitschrift für anorganische und allgemeine Chemie, EarlyView.
Titanocene phosphinidenes react with terminal alkynes in formal [2 + 2] cycloadditions to give unsaturated [C2PTi] metallcycles. Diphosphene complexes in combination with aryl‐substituted alkynes react similarly to provide metallacyclopentenes. Titanocene‐phosphinidene and diphosphanediide (or diphosphene) complexes Cp2Ti(PMe3)PMesTer and Cp2Ti(P2Ar2) (
Andrey Petrov, Christian Hering‐Junghans   +1 more
wiley   +1 more source

Synthesis of Benzopyranophenazines via Isocyanide-Based Three-Component Reactions

E-Journal of Chemistry, 2012
Benzo[a]pyrano[2,3-c]phenazines were synthesized in good yields by a three-component reaction of benzo[a]phenazin-5-oles, isocyanides and dialkyl acetylendicarboxylates In refluxing ethanol.
Ayoob Bazgir, Ali Mohammad Astaraki
doaj   +1 more source

Draft genome of Neofabraea vagabunda, the agent of bull's eye rot

Annals of Applied Biology, Volume 188, Issue 3, Page 941-946, May 2026.
Circular representation of the 12 major scaffolds from the draft genome of Neofabraea vagabunda showing gene density, density of repeated regions, GC content, and functional features (secrete and membrane proteins, proteases, and CAZymes) distribution.
Saveria Mosca, Antonino Malacrinò, Nesma Zakaria Mohamed, Martina Lucci, Alessandra Di Francesco   +4 more
wiley   +1 more source

Partial Sigma Covalent Bonding in Transition Metals

Journal of Computational Chemistry, Volume 47, Issue 11, 30 April 2026.
This study demonstrates partial σ‐covalent bonding is a general electronic phenomenon spanning main‐group biradicals and d8–d8 transition‐metal systems (Co, Rh, Ir). The analyses in this study reveal that ligand field (Dimen and Lantern organic frameworks) and orbital symmetry govern metal–metal interactions, with different bonding expressions ...
Lam H. Nguyen, Thanh N. Truong
wiley   +1 more source

Microwave-Assisted Synthesis of Novel Functionalized Ketenimines and Azadienes via a Solvent-Free Reaction of Isatoic Anhydride, Alkyl-Isocyanides and Dialkyl Acetylenedicarboxylates [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2019
Ketenimines and azadienes are transient intermediates in organic chemistry especially in elimination-addition processes and in the formation of heterocyclic systems.
Samira Arab-Salmanabadi
doaj  

Koordinationschemie perhalogenierter Cyclopentadiene und Alkine, X [PDF]

, 1992
Coordination Chemistry of Perhalogenated Cyclopentadienes and Alkynes, X[1]. - Synthesis and Molecular Structure of a Cyclopentadienyl-1,3-dithiol Complex, [C5Cl3(SH)2]Mn(CO)3 The reaction of [C5Cl4Li]Mn(CO)3 with elemental sulfur leads to [C5Cl4SLi]Mn(
Akabori, Davison, Egger, Fest, Herberhold, Herberhold, Mueller-Westerhoff, Müller, Peter, Sergheraert, Seyferth, Sidebotham, Sünkel, Sünkel, Sünkel, Sünkel   +15 more
core   +1 more source