Results 61 to 70 of about 202,861 (363)

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

open access: yesFEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang   +7 more
wiley   +1 more source

Therapeutic potential of the nitrite-generated NO pathway in vascular dysfunction.

open access: yesFrontiers in Immunology, 2013
Nitric oxide (NO) generated through L-arginine metabolism by endothelial nitric oxide synthase (eNOS) is an important regulator of the vessel wall. Dysregulation of this system has been implicated in various pathological vascular conditions, including ...
Michael eMadigan, Brian eZuckerbraun
doaj   +1 more source

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

open access: yesFEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui   +5 more
wiley   +1 more source

Improved Mechanical Performance of Epoxy Systems with Low Loadings of Milled Carbon Fiber via Chemical Surface Modification

open access: yesAdvanced Engineering Materials, EarlyView.
The authors explore thermally initiated diazonium chemical surface modification as a means of improving the mechanical performance of milled carbon fibers in epoxy matrix systems at varying loadings by weight. They report significant improvements at <1% w/w loading through examination of flexural and tensile strength and modulus.
Ben Newman   +4 more
wiley   +1 more source

Silver(I) complexes with nitrile ligands: new materials with versatile applications [PDF]

open access: yesAppl Organomet Chem. 2023;37:e7207
In the present study, the structure, thermal stability, conductive properties, and antimicrobial activity of silver(I) complexes with nitrile ligands were investigated. For the construction of the materials, 2 cyanopyridine (2-cpy), 4-cyanopyridine (4-cpy), 1,2-dicyanobenzene (1,2-dcb), and 1,3 dicyanobenzene (1,3-dcb) were used in addition to the ...
arxiv   +1 more source

Calibration of the NDHA model to describe N2O dynamics from respirometric assays [PDF]

open access: yes, 2017
The NDHA model comprehensively describes nitrous oxide (N2O) producing pathways by both autotrophic ammonium oxidizing and heterotrophic bacteria. The model was calibrated via a set of targeted extant respirometric assays using enriched nitrifying biomass from a lab-scale reactor.
arxiv   +1 more source

Application of Graphene-Based Materials for Detection of Nitrate and Nitrite in Water—A Review

open access: yesItalian National Conference on Sensors, 2019
Nitrite and nitrate are widely found in various water environments but the potential toxicity of nitrite and nitrate poses a great threat to human health. Recently, many methods have been developed to detect nitrate and nitrite in water.
Daoliang Li   +5 more
semanticscholar   +1 more source

Reaction mixtures formed by nitrite and selected sulfa-drugs showed mutagenicity in acidic medium

open access: yesQuímica Nova, 2009
Nitrite, which is present in preserved meat and can be produced in the oral cavity by reduction of nitrate taken from vegetables, could react in stomach with nitrosatable drugs, giving genotoxic-carcinogenic N-nitroso compounds (NOC). The mutagenicity of
Claudia Trossero   +7 more
doaj   +1 more source

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

open access: yesAdvanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto   +2 more
wiley   +1 more source

Stability of Nitrogen in Planetary Atmospheres in Contact with Liquid Water [PDF]

open access: yes, 2019
Molecular nitrogen is the most commonly assumed background gas that supports habitability on rocky planets. Despite its chemical inertness, nitrogen molecule is broken by lightning, hot volcanic vents, and bolide impacts, and can be converted into soluble nitrogen compounds and then sequestered in the ocean.
arxiv   +1 more source

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