Results 141 to 150 of about 50,424 (297)

Increase of reactive oxygen species by desferrioxamine during experimental Chagas' disease. [PDF]

open access: yes, 2010
Oxidative stress is common in inflammatory processes associated with many diseases including Chagas' disease. The aim of the present study was to evaluate, in a murine model, biomarkers of oxidative stress together with components of the antioxidant ...
Arantes, Jerusa Marilda   +10 more
core   +2 more sources

Redirecting Intermediary Metabolism to Counteract Cyanide Poisoning

open access: yesThe FASEB Journal, Volume 39, Issue 12, 30 June 2025.
Cyanide is coined “the classic metabolic poison”; however, FDA‐approved cyanide chelators do not counteract cyanide's metabolic damage. Here, we review the mechanisms of cyanide toxicity, with a focus on intermediary metabolism. We present the theory that, within the innate plasticity of the metabolome, there may reside metabolic pathways that can ...
Vik S. Bebarta, Anjali K. Nath
wiley   +1 more source

Superoxide reductase from Desulfoarculus baarsii [PDF]

open access: yesMethods in Enzymology, Elsevier, 2001, 349, pp.123-9, 2014
Superoxide radical (O2.-) is the univalent reduction product of molecular oxygen and belongs to the group of the so-called toxic oxygen derivatives. For years the only enzymatic system known to catalyze the elimination of superoxide was the superoxide dismutase (SOD), which catalyzes dismutation of superoxide radical anions to hydrogen peroxide and ...
arxiv  

Nitrogen Oxyanion-dependent Dissociation of a Two-component Complex That Regulates Bacterial Nitrate Assimilation [PDF]

open access: yes, 2013
Nitrogen is an essential nutrient for growth and is readily available to microbes in many environments in the form of ammonium and nitrate. Both ions are of environmental significance due to sustained use of inorganic fertilizers on agricultural soils ...
Goldman   +6 more
core   +1 more source

Purine Chemistry in the Early RNA World at the Origins of Life: From RNA and Nucleobases Lesions to Current Key Metabolic Routes

open access: yesChemBioChem, Volume 26, Issue 11, June 3, 2025.
In the nascent processes of the beginnings and evolution of life, nucleobases and especially purines, ribonucleos(t)ides and primitive RNAs have been continuously modified. A RNA‐peptide world and key metabolic pathways probably have emerged from the corresponding chemical modifications resulting from adenine deamination, purine alkylation and ...
Jean‐Luc Décout   +1 more
wiley   +1 more source

A QM/MM Study of Nitrite Binding Modes in a Three-Domain Heme-Cu Nitrite Reductase

open access: yesMolecules, 2018
Copper-containing nitrite reductases (CuNiRs) play a key role in the global nitrogen cycle by reducing nitrite (NO2−) to nitric oxide, a reaction that involves one electron and two protons.
Kakali Sen   +4 more
doaj   +1 more source

Pseudomonas chloritidismutans sp. nov., a non-denitrifying chlorate-reducing bacterium [PDF]

open access: yes, 2002
A Gram-negative, facultatively anaerobic, rod-shaped, dissimilatory chlorate-reducing bacterium, strain AW-1(T), was isolated from biomass of an anaerobic chlorate-reducing bioreactor.
Jonker, A.B.   +3 more
core   +3 more sources

Further Characterization of Ferredoxin Nitrite Reductase and the Relationship between the Enzyme and Methyl Viologen-dependent Nitrite Reductase

open access: yesAgricultural and Biological Chemistry, 1982
Ferredoxin-dependent nitrite reductase of spinach has been further characterized and the relationship between this enzyme and methyl viologen-dependent nitrite reductase studied. Purified ferredoxin nitrite reductase, having a molecular weight of 86, 000, showed 2.5 times higher ferredoxin-dependent activity than methyl viologen-linked activity ...
Masakazu Hirasawa-Soga   +2 more
openaire   +3 more sources

Optimal Selenium Fertilizer Affects the Formation of Foxtail Millet (Setaria italica L.) Quality by Regulating Flavonoid Metabolism and Amino Acid Metabolism

open access: yesFood Science &Nutrition, Volume 13, Issue 6, June 2025.
S2 treatment regulated the flavonoid and histidine metabolism pathways of Jingu 21, reduced the protein content, increased the fat and starch contents, and decreased the peak viscosity and breakdown value. S2 treatment regulated the Stilbenoid, diarylheptanoid, and gingerol pathway of Jingu 40, and S3 treatment activated the tyrosine metabolic pathway ...
Shu Wang   +5 more
wiley   +1 more source

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