Results 161 to 170 of about 292,870 (340)

Deoxymyoglobin Is a Nitrite Reductase That Generates Nitric Oxide and Regulates Mitochondrial Respiration

open access: yesCirculation Research, 2007
Previous studies have revealed a novel interaction between deoxyhemoglobin and nitrite to generate nitric oxide (NO) in blood. It has been proposed that nitrite acts as an endocrine reservoir of NO and contributes to hypoxic vasodilation and signaling ...
S. Shiva   +9 more
semanticscholar   +1 more source

Role of Inflammatory and Proresolving Mediators in Endothelial Dysfunction

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 136, Issue 5, May 2025.
ABSTRACT Excessive local inflammation is a common mechanism in many cardiovascular diseases (CVDs) such as hypertension, atherosclerosis and aortic aneurysms. In endothelial cells, inflammatory cytokines such as interferons, tumour necrosis factor alpha or interleukins increase oxidative stress and contractile prostanoids and the expression of adhesion
Ana M. Briones   +7 more
wiley   +1 more source

Cyanate Assimilation by the Alkaliphilic Cyanide-Degrading Bacterium Pseudomonas pseudoalcaligenes CECT5344: Mutational Analysis of the cyn Gene Cluster [PDF]

open access: yes, 2019
The alkaliphilic bacterium Pseudomonas pseudoalcaligenes CECT5344 can grow with cyanate, cyanide, or cyanide-containing industrial residues as the sole nitrogen source, but the assimilation of cyanide and cyanate takes place through independent pathways.
Cabello, Purificación   +5 more
core   +1 more source

Modelling N2O dynamics of activated sludge biomass under nitrifying and denitrifying conditions: pathway contributions and uncertainty analysis [PDF]

open access: yesarXiv, 2018
Nitrous oxide (N2O) is a potent greenhouse gas emitted during biological wastewater treatment. A pseudo-mechanistic model describing three biological pathways for nitric oxide (NO) and N2O production was calibrated for mixed culture biomass from an activated sludge process using laboratory-scale experiments.
arxiv  

Nitrite reductase activity of myoglobin regulates respiration and cellular viability in myocardial ischemia-reperfusion injury

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2008
The nitrite anion is reduced to nitric oxide (NO•) as oxygen tension decreases. Whereas this pathway modulates hypoxic NO• signaling and mitochondrial respiration and limits myocardial infarction in mammalian species, the pathways to nitrite ...
U. Hendgen-Cotta   +11 more
semanticscholar   +1 more source

In the nectar, there are answers: exploring the intersection of colored nectars and reactive oxygen species in manipulating pollinator behavior

open access: yesNew Phytologist, Volume 246, Issue 3, Page 901-910, May 2025.
Summary Nectar, a vital mediator of plant–pollinator interactions, exhibits remarkable chemical diversity beyond sugars, including reactive oxygen species and specialized metabolites such as pigments. Colored nectars, present in over 70 species, function as visual signals, inhibitors of microbial growth, or nutritional rewards, underscoring their ...
Evin T. Magner   +3 more
wiley   +1 more source

Niche differentiation in nitrogen metabolism among methanotrophs within an operational taxonomic unit [PDF]

open access: yes, 2014
Background: The currently accepted thesis on nitrogenous fertilizer additions on methane oxidation activity assumes niche partitioning among methanotrophic species, with activity responses to changes in nitrogen content being dependent on the in situ ...
Boon, Nico   +5 more
core   +3 more sources

Superoxide reductase from Desulfoarculus baarsii [PDF]

open access: yesMethods in Enzymology, Elsevier, 2001, 349, pp.123-9, 2014
Superoxide radical (O2.-) is the univalent reduction product of molecular oxygen and belongs to the group of the so-called toxic oxygen derivatives. For years the only enzymatic system known to catalyze the elimination of superoxide was the superoxide dismutase (SOD), which catalyzes dismutation of superoxide radical anions to hydrogen peroxide and ...
arxiv  

Enhancing nitrite reductase activity of modified hemoglobin: bis-tetramers and their PEGylated derivatives.

open access: yesBiochemistry, 2009
The clinical evaluation of stabilized tetrameric hemoglobin as alternatives to red cells revealed that the materials caused significant increases in blood pressure and related problems and this was attributed to the scavenging of nitric oxide and ...
Francine E. Lui, R. Kluger
semanticscholar   +1 more source

Nitrogen Assimilation Plays a Role in Balancing the Chloroplastic Glutathione Redox Potential Under High Light Conditions

open access: yesPlant, Cell &Environment, Volume 48, Issue 5, Page 3559-3572, May 2025.
ABSTRACT Nitrate reduction requires reducing equivalents produced by the photosynthetic electron transport chain. Therefore, it has been suggested that nitrate assimilation provides a sink for electrons under high light conditions. We tested this hypothesis by monitoring photosynthetic efficiency and the chloroplastic glutathione redox potential (chl ...
Gal Gilad   +8 more
wiley   +1 more source

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