Results 201 to 210 of about 3,240,611 (236)

A single‐molecule prodrug synergistically suppresses MYC‐amplified osteosarcoma through sequential nitric oxide release and photodynamic therapy

open access: yesSmart Molecules, EarlyView.
A cascade‐responsive small‐molecule prodrug (DHU‐NO3) sequentially releases methylene blue (triggered by reactive oxygen species) and nitric oxide (controlled by 405 nm light), enabling precise spatiotemporal coordination of photodynamic therapy and NO gas therapy to effectively inhibit MYC‐amplified osteosarcoma growth.
Shuxin Peng   +12 more
wiley   +1 more source

Cyanogenic Compounds, Physicochemical Parameters and Metals in Water From Cassava Processing Areas: A Study in the Brazilian Amazon, Using Multivariate Analysis

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT This study evaluated the water quality of artesian wells and effluents generated in cassava processing in a rural area of Bragança, Pará, with emphasis on physicochemical parameters, multielement composition, and cyanogenic compounds. The well water presented specific nonconformities, highlighting pH values below the recommended level and high
Alana Coêlho Maciel   +13 more
wiley   +1 more source

Maternal Lead Exposure Induces Glandular Alterations in the Salivary Glands of Rat Male Offspring

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Lead (Pb) is a widely distributed environmental pollutant that is highly noxious due to its toxicokinetic characteristics. Pb exposure can damage vital organ systems, including the central nervous and stomatognathic systems. As salivary glands play an important role in oral homeostasis, this study aimed to investigate the effects of maternal ...
Rayssa Maitê Farias Nazário   +8 more
wiley   +1 more source

Nitrate Toxicity in Ruminant Production Systems. [PDF]

open access: yesAnimals (Basel)
Haines G   +3 more
europepmc   +1 more source

Climate‐Modulated Particle Toxicity: Acute Exposure to an Environmentally Informed Microplastic Mixture Induces Sex‐Dependent Systemic Reorganization in Swiss Mice

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Microplastic (MP) pollution is widely recognized as an emerging environmental threat. Yet, most studies still rely on controlled experimental conditions that poorly reflect environmental complexity, potentially underestimating risks under realistic scenarios, particularly during short‐term exposures. Here, we tested whether acute oral exposure
Guilherme Malafaia   +5 more
wiley   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

open access: yesVIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe   +8 more
wiley   +1 more source

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