Results 211 to 220 of about 173,810 (326)

Pharmaceuticals Made with Hydrogen: A Sustainable and Efficient Approach Using Flow Synthesis

open access: yesChemistry – A European Journal, EarlyView.
We demonstrate a sustainable strategy for pharmaceutical manufacturing by combining hydrogen, heterogeneous catalysis, and continuous flow synthesis. The development of novel catalysts and their application in a multi‐step synthesis of donepezil enabled a highly productive process with no intermediate purification.
Shū Kobayashi, Haruro Ishitani
wiley   +1 more source

Controlling Competitive Radical Pathways: Insights from Aryl Diazonium Electrografting

open access: yesChemistry – A European Journal, EarlyView.
This work shows that nitrobenzene diazonium electrografting results from competition between aryl and diazenyl radicals, which govern film composition. Using simulations and control strategies, grafting conditions are tuned to favor specific radicals. It enables selective formation of azo‐enriched films and paves the way toward the precise control of ...
Sara Helis   +5 more
wiley   +1 more source

The versatility of nitro compounds [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 1976
J M, Hamilton-Miller, W, Brumfitt
openaire   +2 more sources

Photoinduced, Chemoselective γ‐Alkylation of 2‐Silyloxyfurans with α‐Bromoketones: A Rapid Entry to Chiral ε‐Keto‐γ‐Butenolides

open access: yesChemistry – A European Journal, EarlyView.
A photoinduced, regio‐ and chemoselective γ‐alkylation of 2‐silyloxyfurans with a‐bromoketones was achieved by exploiting a photoredox catalytic process promoted by blue light. This approach provides practical and efficient access to chiral, ε‐ketobutenolides, in one step and high yields.
Debora Guazzetti   +9 more
wiley   +1 more source

Catalytic Amyloids: Turning Fibrils Into Biocatalysts

open access: yesChemistry – A European Journal, EarlyView.
Amyloids, traditionally associated with diseases, have emerged as versatile catalytic scaffolds. From natural amyloid sequences to bioinspired and de novo designs, we highlight strategies to construct catalytic active sites and anchor enzymes onto fibrils, creating versatile nanomaterials with tunable activities. ABSTRACT Amyloids have been regarded as
Alessandra Esposito   +3 more
wiley   +1 more source

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