Results 231 to 240 of about 106,125 (294)

Structure-enabled enhancement of potency in a metronidazole-benznidazole hybrid: design, synthesis, and evaluation of antitrypanosomal activity of a benzylamide-linked 5-nitroimidazole. [PDF]

Front Pharmacol
Velez ASMM, Chaves OA, Costa T, Serpa C, Borges JM, Freire-de-Lima CG, Decote-Ricardo D, Lima MEF.   +7 more
europepmc   +1 more source

Controlled transfer-reduction of functional groups with ethanol by their interaction strength with the oxygen vacancies. [PDF]

Nat Commun
Yuan Z, Yao Z, Tang Q, Ren Y, Wang J, Zhou P, Zhang Z.   +6 more
europepmc   +1 more source

Regioselective approach to 5-arylsulfonylisoxazoles and their antimicrobial activity. [PDF]

Beilstein J Org Chem
Sazonov AS, Vasilenko DA, Porfiriev DV, Grishin YK, Gazzaeva RA, Chernyshova AP, Kryakvin MA, Baranova AA, Alferova VA, Averina EB.   +9 more
europepmc   +1 more source

A study of the effects of groups and their position on the rate of reduction of the nitro group of some benzene nitro compounds

, 1929
openaire   +1 more source

Nitro-Group-Containing Drugs

Journal of Medicinal Chemistry, 2018
The nitro group is considered to be a versatile and unique functional group in medicinal chemistry. Despite a long history of use in therapeutics, the nitro group has toxicity issues and is often categorized as a structural alert or a toxicophore, and evidence related to drugs containing nitro groups is rather contradictory.
Kunal Nepali, Hsueh-Yun Lee, Jing-Ping Liou   +2 more
openaire   +3 more sources

Charge-Transfer-Induced Twisting of the Nitro Group

The Journal of Physical Chemistry A, 2007
Excited-state relaxation dynamics of 2-amino-7-nitrofluorene (ANF) and 2-dimethylamino-7-nitrofluorene (DMANF) has been investigated in two aprotic solvents, namely acetonitrile and DMSO using femtosecond transient absorption spectroscopic technique.
Jahur A, Mondal, Moloy, Sarkar, Anunay, Samanta, Hirendra N, Ghosh, Dipak K, Palit   +4 more
openaire   +3 more sources

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Nitro and related groups

Journal of the Chemical Society, Perkin Transactions 1, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +1 more source

Selective Reduction of an Aromatic Nitro Group to an Azoxy Unit in the Presence of an Aliphatic Nitro Group.

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Ulrich Siemeling, Thomas T�rk, Udo Vorfeld, Heinrich Fink   +3 more
openaire   +1 more source

A new olefin synthesis. Synchronous elimination of nitro and ester groups or nitro and keto groups from .beta.-nitro esters or .beta.-nitro ketones

The Journal of Organic Chemistry, 1983
Synthese de nitriles, esters, cetones et sulfones vinyliques a partir de (chloro-1 nitro-1) ou de (bromo-1 nitro-1 ...
Noboru Ono, Rui Tamura, Hiromichi Eto, Isami Hamamoto, Tamon Nakatsuka, Junichi Hayami, Aritsune Kaji   +6 more
openaire   +1 more source

The position of the nitro group affects the mutagenicity of nitroarenes

Toxicology and Applied Pharmacology, 2022
The ease with which a nitrated polyaromatic hydrocarbon (NO2PAH) is activated by reductive metabolism is an important factor in determining mutagenicity. However, the mutagenicity of 3-nitrobenzo[a]pyrene (3-NO2BaP) is stronger than that of 1-NO2BaP despite similar reduction properties, and the more potent mutagenicity of 3,6-diNO2BaP relative to that ...
Akiko, Ohno, Yoshio, Okiyama, Akihiko, Hirose, Kiyoshi, Fukuhara   +3 more
openaire   +2 more sources