Results 1 to 10 of about 2,022 (179)

Nitroarginine Inhibits Endothelium-Derived Relaxation

Japanese Journal of Pharmacology, 1990
Effects of NG-nitro-L-arginine (NO2Arg), a guanidinonitro arginine derivative, on acetylcholine-induced relaxation of rabbit thoracic aorta ring preparation were studied. Relaxation by acetylcholine was inhibited by NO2Arg dose-dependently and the maximum relaxation with 10(2) microM NO2Arg was reduced to 10.1 +/- 4.3% (n = 5). L-arginine (10(2) microM)
Y, Kobayashi, K, Hattori
  +5 more sources

Ginkgo biloba leaf extract (EGb 761) enhances catalepsy induced by haloperidol and L-nitroarginine in mice [PDF]

Brazilian Journal of Medical and Biological Research, 2005
Ginkgo biloba extract EGb 761 has been reported to have therapeutic effects which have been attributed to anti-oxidant and free radical-scavenging activities, including a direct action on nitric oxide production.
L. Fontana, A.S. Souza, E.A. Del Bel, R.M.W. de Oliveira   +3 more
doaj   +2 more sources

N-Acetylcysteine and N-Nitroarginine Methyl Ester Attenuate Carboplatin-Induced Ototoxicity in Dissociated Spiral Ganglion Neuron Cultures [PDF]

Clinical and Experimental Otorhinolaryngology, 2011
ObjectivesCarboplatin, a platinum-containing anti-cancer drug used to treat a variety of cancers, induces ototoxicity. Since, reactive oxygen species (ROS) and nitric oxide (NO) seem to be responsible for this toxicity, the antioxidant, N-acetyl-L ...
Il Joon Moon, Ki Ryung Kim, Ho-Suk Chu, Se Hyung Kim, Won-Ho Chung, Yang-Sun Cho, Sung Hwa Hong   +6 more
doaj   +2 more sources

Single Crystals of α–LiIO3 Doped with L–arginine and L–nitroarginine [PDF]

Armenian Journal of Physics, 2022
One of the essential crystals for technology is the hexagonal modification of lithium iodate (α–LiIO3), which is endowed with nonlinear optical, pyroelectric, piezoelectric, acousto–optic properties. In recent years, a number of research groups studied physical and physiochemical properties of several single crystals (KDP, ADP, BTCA, ZTC) that were ...
A.A. Danghyan
openaire   +2 more sources

Effects of nitric oxide synthase inhibitors, l‐N^G‐nitroarginine and l‐N^G‐nitroarginine methyl ester, on responses to vasodilators of the guinea‐pig coronary vasculature [PDF]

British Journal of Pharmacology, 1992
The effects of l‐NG‐nitroarginine (l‐NOARG) and l‐NG‐nitroarginine methyl ester (l‐NAME) on vasodilatation induced by ATP, substance P, 5‐hydroxytryptamine (5‐HT), bradykinin and sodium nitroprusside (SNP) were examined in the guinea‐pig coronary bed, by use of a Langendorff technique.
A, Vials, G, Burnstock
openaire   +4 more sources

Quinapril Prevents Hypertension and Enhanced Vascular Reactivity in Nitroarginine-treated Rats [PDF]

Blood Pressure, 1997
Long-term inhibition of nitric oxide synthase (NOS) by substituted arginine analogues has previously been shown to induce systemic hypertension in several animal species; however, the precise mechanisms for the elevated blood pressure remain unclear.
J R, Charpie, P M, Charpie, C, Goud, B, Pitt, R C, Webb   +4 more
openaire   +3 more sources

Study of L-nitroarginine perchlorate and L-nitroarginine tetrafluoroborate crystals

Journal of Physics: Conference Series
Abstract In the present work, we report the results of vibrational spectroscopic (Fourier transform IR and Raman), UV-Vis transmission, thermal properties, and nonlinear optical activity of L-nitroarginine perchlorate (L-NNA·HClO4) and L-nitroarginine tetrafluoroborate (L-NNA·HBF4) crystals. The NLO activity of crystals was measured. All
R P Sukiasyan, R A Apreyan, A A Danghyan, N S Gharibyan, A K Atanesyan   +4 more
openaire   +2 more sources

RETRACTED: Neuroprotective Role of L-NG-Nitroarginine Methyl Ester (L-NAME) against Chronic Hypobaric Hypoxia with Crowding Stress (CHC) Induced Depression-Like Behaviour.

PLoS ONE, 2016
Improper neuroimmune responses following chronic stress exposure have been reported to cause neuronal dysfunctions leading to memory impairment, anxiety and depression like behaviours. Though several factors affecting microglial activation and consequent
Satya Narayan Deep, Iswar Baitharu, Apurva Sharma, Anoop Kishor Singh Gurjar, Dipti Prasad, Shashi Bala Singh   +5 more
doaj   +3 more sources

Role of potassium channels in endothelium‐dependent relaxation resistant to nitroarginine in the rat hepatic artery [PDF]

British Journal of Pharmacology, 1996
1. In the presence of indomethacin (IM, 10 microM) and N omega-nitro-L- arginine (L-NOARG, 0.3 mM), acetylcholine (ACh) induces an endothelium-dependent smooth muscle hyperpolarization and relaxation in the rat isolated hepatic artery. The potassium (K) channel inhibitors, tetrabutylammonium (TBA, 1 mM) and to a lesser extent 4-aminopyridine (4-AP, 1 ...
P M, Zygmunt, E D, Högestätt
openaire   +4 more sources

Effects of nitroarginine on endothelium-dependent relaxation of canine basilar artery

Japanese Journal of Pharmacology, 1990
Fumihito Ohta, Yuta Kobayashi, Keiko Shimoura, Keisuke Hattori, Kouzo Moritake   +4 more
openaire   +2 more sources