Results 91 to 100 of about 2,041 (198)

A roadmap for therapeutic discovery in pulmonary hypertension associated with left heart failure. A scientific statement of the Heart Failure Association (HFA) of the ESC and the ESC Working Group on Pulmonary Circulation & Right Ventricular Function

open access: yesEuropean Journal of Heart Failure, Volume 26, Issue 4, Page 707-729, April 2024.
Pulmonary hypertension (PH) associated with left heart failure (LHF) (PH‐LHF) is one of the most common causes of PH. It directly contributes to symptoms and reduced functional capacity and negatively affects right heart function, ultimately leading to a poor prognosis.
Pietro Ameri   +39 more
wiley   +1 more source

Insights into the influence of diet and genetics on feed efficiency and meat production in sheep

open access: yesAnimal Genetics, Volume 55, Issue 1, Page 20-46, February 2024.
Abstract Feed costs and carcass yields affect the profitability and sustainability of sheep production. Therefore, it is crucial to select animals with a higher feed efficiency and high‐quality meat production. This study focuses on the impact of dietary and genetic factors on production traits such as feed efficiency, carcass quality, and meat quality.
Steffimol Rose Chacko Kaitholil   +4 more
wiley   +1 more source

A key role for peroxynitrite-mediated inhibition of cardiac ERG (Kv11.1) K+ channels in carbon monoxide–induced proarrhythmic early afterdepolarizations [PDF]

open access: yes, 2017
Exposure to carbon monoxide (CO) causes early afterdepolarization arrhythmias. Previous studies in rats indicated arrhythmias arose due to augmentation of the late Na+ current.
Chris Peers   +8 more
core   +2 more sources

Evaluation of Nicorandil in Treatment of induced pulmonary arterial hypertension in male Rats

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences
Pulmonary arterial hypertension (PAH) is a chronic, rare, and non-treatable disease, resulting in elevated mean arterial pressure (≥25mmHg) during rest and (≥30mmHg) during exercise.
Taha Hashim Ahmed   +2 more
doaj   +1 more source

Nitric oxide regulates synaptic transmission between spiny projection neurons [PDF]

open access: yes, 2014
Recurrent axon collaterals are a major means of communication between spiny projection neurons (SPNs) in the striatum and profoundly affect the function of the basal ganglia.
Greengard, Paul   +9 more
core   +1 more source

Nitroarginine does not Inhibit Lysophosphatidylcholine (LPC)-Induced Vascular Relaxation and Accumulation of Cyclic GMP

open access: yesExperimental Biology and Medicine, 1991
Lysophosphatidylcholine (LPC) is a potent endothelium-dependent vascular smooth muscle relaxant. The possibility that its action is mediated through endothelium-derived nitric oxide (EDNO), although suggestive, has not been proven. Both lysophosphatidylcholine and endothelium-derived nitric oxide relax by activating guanylate cyclase to form cyclic GMP.
N K, Menon, R J, Bing
openaire   +2 more sources

Nitric Oxide Synthase Is Involved in Follicular Development via the PI3K/AKT/FoxO3a Pathway in Neonatal and Immature Rats

open access: yesAnimals, 2020
It is assumed that nitric oxide synthase and nitric oxide are involved in the regulation of female reproduction. This study aimed to assess the roles of nitric oxide synthase (NOS) in follicular development.
Junrong Li   +3 more
doaj   +1 more source

Contribution of hydrogen sulfide to the control of coronary blood flow [PDF]

open access: yes, 2014
This study examined the mechanisms by which H2S modulates coronary microvascular resistance and myocardial perfusion at rest and in response to cardiac ischemia. Experiments were conducted in isolated coronary arteries and in open-chest anesthetized dogs.
Berwick, Zachary C.   +5 more
core   +1 more source

Granulocyte-Colony Stimulating Factor Increases Cerebral Blood Flow via a NO Surge Mediated by Akt/eNOS Pathway to Reduce Ischemic Injury

open access: yesThe Scientific World Journal, 2015
Granulocyte-colony stimulating factor (G-CSF) protects brain from ischemic/reperfusion (I/R) injury, and inhibition of nitric oxide (NO) synthases partially reduces G-CSF protection.
Hock-Kean Liew   +3 more
doaj   +1 more source

Effects of diclofenac, L-NAME, L-Arginine, and pentadecapeptide BPC 157 on gastrointestinal, liver, and brain lesions, failed anastomosis, and intestinal adaptation deterioration in 24 hour-short-bowel rats [PDF]

open access: yes, 2016
Stable gastric pentadecapeptide BPC 157 was previously used to ameliorate wound healing following major surgery and counteract diclofenac toxicity. To resolve the increasing early risks following major massive small bowel resectioning surgery, diclofenac
Drmić, Domagoj   +9 more
core   +2 more sources

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