Results 101 to 110 of about 2,041 (198)
Libyan Journal of Medicine, 2017 Introduction: Nitrite has been found to protect liver graft from cold preservation injury. However, the cell signaling pathway involved in this protection remains unclear. Here, we attempt to clarify if the NOS pathway by using the NOS inhibitor, L-NAME (
Amani Cherif-Sayadi +6 more
doaj +1 more source
Ammonia toxicity to the brain [PDF]
, 2018 Hyperammonemia can be caused by various acquired or inherited disorders such as urea cycle defects. The brain is much more susceptible to the deleterious effects of ammonium in childhood than in adulthood.
Braissant, Olivier +2 more
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Synthesis of Dihydro-1,2,4-Triazin-6-one Containing Nitroarginine Moiety
, 2009 Nitrilimines (2), react with nitroarginine methyl ester (3) at room temperature, through cyclocondensation reaction, to give 1-aryl-3-substituted-1,2,4-triazin-6-ones (4a-k). The structure of these compounds was deduced from: elemental analysis, IR, mass spectra, 1H and 13C NMR.
Abu Thaher, Bassam A. +3 more
openaire +1 more source
Chronic Kidney Disease Increases Cerebral Microbleeds in Mouse and Man. [PDF]
, 2020 Brain microbleeds are increased in chronic kidney disease (CKD) and their presence increases risk of cognitive decline and stroke. We examined the interaction between CKD and brain microhemorrhages (the neuropathological substrate of microbleeds) in ...
Bangash, Maria +13 more
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Changes in murine anorectum signaling across the life course [PDF]
, 2018 Background: Increasing age is associated with an increase in the incidence of chronic constipation and fecal impaction. The contribution of the natural aging process to these conditions is not fully understood.
Fidalgo, S. +4 more
core +4 more sources
International Brazilian Journal of Urology, 2014 Purpose The aim of this study was to define if tadalafil causes detrusor muscle impairment and to observe the effect of combination of tadalafil with tamsulosin on the lower urinary tract of rats with bladder outlet obstruction (BOO) induced by chronic ...
Rommel Prata Regadas +6 more
doaj +1 more source
Signalling Mechanisms Underlying Doxorubicin and Nox2 NADPH Oxidase-Induced Cardiomyopathy: Involvement of Mitofusin-2 [PDF]
, 2017 BACKGROUND AND PURPOSE: The anthracycline doxorubicin (DOX), although successful as a first-line cancer treatment, induces cardiotoxicity linked with increased production of myocardial reactive oxygen species (ROS), with Nox2 NADPH oxidase-derived ...
Dunne, Philip D +7 more
core +1 more source
Diagnostic Ultrasound High Mechanical Index Impulses Restore Microvascular Flow In Peripheral Arterial Thromboembolism [PDF]
, 2016 We sought to explore mechanistically how intermittent high-mechanical-index (MI) diagnostic ultrasound impulses restore microvascular flow. Thrombotic microvascular obstruction was created in the rat hindlimb muscle of 36 rats.
Everbach, E. Carr +8 more
core +2 more sources
Naringenin inhibits pacemaking activity in interstitial cells of Cajal from murine small intestine
Integrative Medicine Research, 2017 Background: Naringenin (NRG) is a common dietary polyphenolic constituent of fruits. NRG has diverse pharmacological activities, and is used in traditional medicine to treat various diseases including gastrointestinal (GI) disorders.
Hyun Jung Kim, Byung Joo Kim
doaj +1 more source
In-Vitro evaluation of hydroalcoholic extract of Allium ampeloprasum on rat ileum contractions [PDF]
, 2014 Background: Ampeloprasum is traditionally used for gastrointestinal disorders. In this experimental study, the effect of ethanolic extract of Allium ampeloprasum was investigated on the rat ileum contractions. The mechanisms were also evaluated. Methods:
Hadi, Molouk. +4 more
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