Results 161 to 170 of about 2,041 (198)

Ammonolysis of Nitroarginine and Nitroarginine‐Containing Peptides; Some Side Reactions

Helvetica Chimica Acta, 1974
AbstractAmmonolysis of nitroarginine‐containing peptides leads to the formation of ornithine‐containing side products. The structure of these side products has been deduced from model experiments. This side reaction can be avoided by using the NG‐tosyl or the NG‐dicarbobenzoxy protecting groups.
Hans Künzi, Michael Manneberg, Rolf O. Studer   +2 more
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L-Nitroarginine monohydrochloride monohydrate

Acta Crystallographica Section C Crystal Structure Communications, 1994
Two conformers are present in the asymmetric unit of the title compound, C 6 H 14 N 5 O 4 + .CL - .H 2 O, whose conformational differences are characterized by rotations bout the C α -C β and C δ -N e bonds. The nitroguanidyl moieties of both conformers are nearly planar; each is involved in an intramolecular hydrogen bond between the N e atom and ...
N. Okabe, Y. Kohyama, K. Ikeda, S. Sunano   +3 more
openaire   +1 more source

ChemInform Abstract: AMMONOLYSIS OF NITROARGININE AND NITROARGININE‐CONTAINING PEPTIDES, SOME SIDE REACTIONS

Chemischer Informationsdienst, 1974
AbstractDie Ammonolyse von NG‐Nitroarginin‐haltigen Peptiden führt zur Bildung Omithinhaltiger Nebenprodukte.
HANS KUENZI, MICHAEL MANNEBERG, ROLF O. STUDER   +2 more
openaire   +1 more source

L‐NITROARGININE INCREASES BLOOD PRESSURE IN THE RAT

Clinical and Experimental Pharmacology and Physiology, 1991
SUMMARY1. Effects of administration of NG‐nitro‐L‐arginine (NO2Arg), a guanidino nitroarginine derivative, for 1 week on blood pressure and some vascular responses of rats were studied.2. A significant rise of the systolic blood pressure was observed after the administration of NO2Arg with food (0.023% in weight, about 2.8 mg of NO2Arg per rat per day).
Y, Kobayashi, K, Ikeda, K, Shinozuka, Y, Nara, Y, Yamori, K, Hattori   +5 more
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Effect of nitroarginine on phenylalanine under acid hydrolytic conditions

Analytical Biochemistry, 1971
Abstract When peptides containing phenylalanine and nitroarginine were hydrolyzed with hydrochloric acid the former amino acid was chlorinated to give a mixture of isomeric monochlorophenylalanines which were separated and identified. The effects on other susceptible amino acids have been examined. The implications on the interpretation of amino acid
P, Moritz, R, Wade
openaire   +2 more sources

On molecular structure of l-nitroarginine

Journal of Molecular Structure, 2008
Abstract We have found a new form of l -nitroarginine (β-form), which, unlike the known form (α-form) can be obtained in the form of single crystal. The crystal and molecular structures of β-form of l -nitroarginine have been determined and for the first time since the preparation of l -nitroarginine (1911) it has been shown that nitroarginine has
R.A. Apreyan, H.A. Karapetyan, A.M. Petrosyan   +2 more
openaire   +1 more source

Mobile Proton Triggered Radical Fragmentation of Nitroarginine Containing Peptides

Journal of the American Society for Mass Spectrometry, 2014
Protonated nitroarginine, [R(NO2) + H](+), which contains the nitroguanidine 'explosophore,' undergoes homolytic N - N nitro-imine bond cleavage to expel NO2(•) and form a radical cation of arginine in high yield (100% relative abundance) upon low-energy collision-induced dissociation (CID). Other ionization states of nitroarginine, including [R(NO2) -
Leeming, MG, White, JM, O'Hair, RAJ, Donald, WA   +3 more
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Nitroarginine methyl ester and canavanine lower intracellular reduced glutathione

Free Radical Biology and Medicine, 2003
In rat glial cells, arginine analogs N(G)-nitroarginine methyl ester (both D- and L-stereoisomer) and L-canavanine lower the intracellular levels of reduced glutathione, stimulate the pentose phosphate pathway, increase the level of malonyldialdehyde, and increase the leakage of lactate dehydrogenase.
RIGANTI, Chiara, ALDIERI, Elisabetta, BERGANDI, Loredana, MIRAGLIA, ERICA, COSTAMAGNA, Costanzo, BOSIA, Amalia, GHIGO, Dario Antonio   +6 more
openaire   +2 more sources

L-Nitroarginine Reduces Hippocampal Mediation of Place Learning in the Rat

Neurobiology of Learning and Memory, 1995
Based on previous results it was hypothesized that the neural substrate of the acquisition of place learning during inhibition of the nitric oxide synthesizing enzyme (NOS) by L-nitroarginine (L-N-ARG) differs from the neural substrate of normal task acquisition by a reduced or abolished participation of the hippocampus.
Mogensen, Jesper, Wörtwein, Gitta, Gustafson, Bettina, Ermens, Petra   +3 more
openaire   +2 more sources

Selective inhibition of constitutive nitric oxide synthase by L-NG-nitroarginine

Biochemistry, 1993
L-NG-Nitroarginine (NA) inhibited both the L-arginine oxidation and the L-arginine-independent NADPH oxidation reactions catalyzed by the calcium/calmodulin-dependent constitutive nitric oxide synthase (cNOS) from bovine brain. NA binding did not require calmodulin, calcium, or NADPH.
E S, Furfine, M F, Harmon, J E, Paith, E P, Garvey   +3 more
openaire   +2 more sources