Estrogen stimulates dimethylarginine dimethylaminohydrolase activity and the metabolism of asymmetric dimethylarginine. [PDF]
, 2003 Background— Experimental evidence suggests that estrogens stimulate the production of nitric oxide (NO) by vascular endothelial cells. This effect has been attributed to increased expression and enzymatic activity of both the constitutive and inducible ...
Cartwright, JE +3 more
core +1 more source
The influence of nitric oxide on perigeniculate GABAergic cell activity in the anaesthetized cat [PDF]
, 1996 [Abstract] We have tested the effect of iontophoretic application of the nitric oxide synthase inhibitor l-nitroarginine on the activity of a population of 53 perigeniculate (PGN) cells, recorded extracellularly in the anaesthetized paralysed cat. In all
Acuña, Carlos +4 more
core +2 more sources
The effect of L-arginine and L-NAME on myocardial capillary density in normal rats
Advanced Biomedical Research, 2013 Background: This study evaluated the effect of L-arginine (Nitric Oxide (NO) precursor) and L-NG-Nitroarginine Methyl Ester (L-NAME) (NO synthase inhibitor) on myocardial capillary density in normal rats.
Majid Khazaei +7 more
doaj +1 more source
Vasorelaxation effect of oxysophoridine on isolated thoracicc aorta rings of rats
Chinese Journal of Physiology, 2021 Oxysophoridine (OSR) is a main active alkaloid extracted from Sophora alopecuroides, which is a traditional Chinese herbal medicine that has been used widely.
Nan Li +6 more
doaj +1 more source
Tonic and phasic nitric oxide signals in hippocampal long-term potentiation [PDF]
, 2006 Nitric oxide ( NO) participates in long-term potentiation (LTP) and other forms of synaptic plasticity in many different brain areas but where it comes from and how it acts remain controversial.
Garthwaite, J, Hopper, RA
core +1 more source
Modulation of mitochondrial capacity and angiogenesis by red wine polyphenols via estrogen receptor, NADPH oxidase and nitric oxide synthase pathways. [PDF]
, 2013 Red wine polyphenolic compounds (RWPC) are reported to exert vasculoprotective properties on endothelial cells, involving nitric oxide (NO) release via a redox-sensitive pathway. This NO release involves the activation of the estrogen receptor-alpha (ERα)
C. Jacques +5 more
core +3 more sources
Omega-3 fatty acids differentially influences embryotoxicity in subtypes of preeclampsia
Clinical and Experimental Hypertension, 2020 Background: Early (EOP) and late onset (LOP) preeclampsia are two subtypes of preeclampsia. This study examines the effect of maternal omega-3 fatty acids and vitamin E supplementation in a rat model of preeclampsia.
Vaishali Kasture +4 more
doaj +1 more source
JACC: Basic to Translational Science, 2017 Summary: In patients hospitalized with acute heart failure, temporary serelaxin infusion reduced 6-month mortality through unknown mechanisms. This study therefore explored the cardiovascular effects of temporary serelaxin administration in mice ...
Joseph C. McCarthy, MS +5 more
doaj +1 more source
Preparo da veia safena na cirurgia de revascularização miocárdica: uma nova técnica -no touch- que mantém a parede da veia íntegra e proporciona uma alta perviabilidade imediata [PDF]
, 2003 BACKGROUND: The technique of harvesting the saphenous vein (SV) for coronary artery bypass grafting (CABG) influences the fate of vein grafts. A new no touch (NT) technique of SV preparation was developed where the vein is harvested with a pedicle of ...
Bomfim, Vollmer +7 more
core +3 more sources
Redox regulation of the AMP-activated protein kinase. [PDF]
PLoS ONE, 2010 Redox state is a critical determinant of cell function, and any major imbalances can cause severe damage or death.The aim of this study is to determine if AMP-activated protein kinase (AMPK), a cellular energy sensor, is activated by oxidants generated ...
Yingying Han +4 more
doaj +1 more source