Results 91 to 100 of about 2,815 (210)
Veterinary drugs play a crucial role in ensuring the healthy development of the livestock industry. However, improper or excessive use of veterinary drugs may pose threats to the environment and human health. To achieve effective monitoring of veterinary
HAN Yanrong +4 more
doaj +1 more source
Nitrofurans have been widely used either in waterbath or feed additives for the prevention and treatment of aquatic products. The European Union was able to assign a maximum residue limit and prohibited nitrofurans used to animals in 1995, because of the
Tsai, Chung-Wei
core
Genotoxicity testing of antiparasitic nitrofurans in the Drosophila wing somatic mutation and recombination test [PDF]
Nifurtimox and eight structurally related 5-nitrofuran compounds active against Trypanosoma cruzi were tested for genotoxicity in the wing somatic mutation and recombination test in Drosophila melanogaster.
Moraga, Angeles Alonso, Graf, Ulrich
core
Stability of radical anions derived from substituted 5-nitrofurans investigated by ESR spectroscopy
It has been found that the decay in dimethylformamide and dimethylformamide-water mixtures of radical anions in five of the investigated 5-nitrofurans is governed by a second-order reaction.
Jiří Volke +4 more
core +1 more source
Nitrofuran-Based STING Inhibitors
The cGAS-STING pathway plays a central role in the host response to foreign DNA. While cGAS-STING signaling is essential for antiviral immunity, aberrant STING activation is observed in amyotrophic lateral sclerosis (ALS), lupus, and autoinflammatory diseases such as Aicardi-Goutières syndrome (AGS) and STING associated vasculopathy with onset in ...
Leonard Barasa +17 more
openaire +2 more sources
Pentacyclic nitrofurans that rapidly kill nifurtimox-resistant trypanosomes
Objectives: In response to reports of Trypanosoma brucei resistance to the nitroaromatic drug nifurtimox, we evaluated the potential of antituberculosis nitrofuran isoxazolines as inhibitors of trypanosome growth. Methods: The susceptibility of T. brucei
Bruhn, David F. +7 more
core +1 more source
Mechanism of activation and primary resistance.
Activity of nitrofurans against M. tuberculosis H37Rv mutants deficient in enzymes required for bioreductive activation of PA-824.
Marcus M. Maddox (520204) +12 more
core +1 more source
Iatrogenic Events During Antibiotic Therapy (Pulmonary Disease)
Antibiotics occupy a leading position among drugs that cause adverse drug reaction (ADR), in Russia as well. Drug-induced pulmonary disease (DIPD), which is the least studied, takes a special place among ADR in antibiotic therapy.
L. I. Dvoretsky +2 more
doaj
A theoretical docking study was conducted on a sample of previously reported nitrofuran derivatives, at the binding sites of Trypanosoma cruzi trypanothione reductase (TR) and human erythrocyte glutathione reductase (GR), in order to examine interaction ...
Paulino, M. +5 more
core +1 more source
The data on the resistance frequency of the diarrheagenic E.coli isolates to antibacterial agents and a specific bacteriophage are presented. The strains were isolated from hospitalized children in St.Petersburg in 2011-2013 and belonged to three groups,
N. V. Gonchar +3 more
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