Results 121 to 130 of about 1,949 (178)
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Effect of activated nitrofurans on DNA
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1975Enzymically activated nitrofurazone reacts with co-valently closed circular DNA (derived from Escherichia coli minicells carrying lambdadv) to give at least two kinds of damage: breaks which are detected on neutral sucrose gradients and alkali-labile lesions in DNA which are converted to breaks when the DNA is subsequently Treated with alkali.
Y, Tu, D R, McCalla
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Polyneuropathy Associated with Nitrofuran Therapy
Archives of Neurology, 1960Furacin (nitrofurazone) has been used for the treatment of metastatic testicular carcinoma because of the disintegration of seminiferous epithelium produced in animals by nitrofurans. 1 Although a beneficial effect on the malignancy has occurred, a severe polyneuropathy has usually developed. Wildermuth's patient, who had received 49 gm.
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Paper chromatography of nitrofuran derivatives
Journal of Chromatography A, 1966Some investigations have been carried out on the paper chromatography of a group of new nitrofuran derivatives, along with three known preparations of the same group, viz. furacin, furadantin and furoxone. Nine solvent systems were employed, and it was established that for the identification and separation of this group of compounds, together with the ...
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Metabolic Degradation of the Nitrofurans
Journal of Medicinal and Pharmaceutical Chemistry, 1960H E, PAUL +3 more
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Journal of the American Pharmaceutical Association (Practical Pharmacy ed.), 1954
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Biological effects of nitrofurans
Journal of Antimicrobial Chemotherapy, 1977openaire +2 more sources