Results 61 to 70 of about 4,069 (227)

Synthesis, Antitubercular Activity, and Computational Characterization of Novel Phenylpyrazole‐Isoniazid Derivatives

Advances in Pharmacological and Pharmaceutical Sciences, Volume 2026, Issue 1, 2026.
Six new phenyl‐1H‐pyrazole‐carbaldehyde isonicotinylhydrazone derivatives 1-10 were synthesized and characterized by spectroscopic (FT‐IR, 1H NMR, and 13C NMR) techniques and electrospray ionization–mass spectrometry (ESI–MS). Homonuclear data from 2D‐NMR (1H‐1H NOESY) revealed that 3 and 5 adopt the transE isomeric form.
Fernando Carrasco, Wilfredo Hernández, Juan Z. Dávalos, Jackeline Mosquera, Oscar Chupayo, Nelly Sivipaucar, Jaime Tamayo, Eduardo Carrasco-S, Jorge Coronel, Osvaldo Yañez, William Tiznado, Anjali Chauhan   +11 more
wiley   +1 more source

Comparative efficacy of nitrofurans in children and adolescents with pyelonephritis in presence of crystalluria

Терапевтический архив, 2013
AIM: To evaluate the efficacy of nitrofurans in children and adolescents with pyelonephritis in the presence of crystalluria/MATERIAL AND METHODS: The study included 50 patients aged 4-14 years with chronic pyelonephritis in the presence of dysmetabolism.
N I Aver'ianova, L G Balueva, N V Ivanova   +2 more
doaj  

Isolation of a Protease‐Producing Microbacterium From the Intestinal Tract of Ruditapes philippinarum and Its Probiotic Effects

Aquaculture Nutrition, Volume 2026, Issue 1, 2026.
Aquatic probiotics are generally recognized as safe and nontoxic live bacterial preparations, primarily sourced from the culturing environment or directly from aquatic organisms. Upon entering the aquatic environment, these probiotics are capable of colonizing both the surface and internal compartments of aquatic organisms, thereby enhancing their ...
Hui Guan, Yaodong Qiu, Mingyue Guan, Sitong Quan, Shang Liu, Yingxu Chen, Haochen Li, Haolin Yu, Lei Fang, Zhongming Huo, Arkadios Dimitroglou   +10 more
wiley   +1 more source

Histopathological alterations in testicular tissue of male rats exposed to arsenic [PDF]

, 2012
The present study was designed to investigate the adverse effect of arsenic on testicular tissue of Swiss albino male rats. Sodium arsenite was administered to adult male rats by gavage at the doses 1, 2 and 3 mg/kg body weight for 30 days.
Pachnanda, Reema, Singh, Shiv Pal
core   +2 more sources

Synthesis and antimicrobial activity of 3,5-R-4-(3-(5-nitrofuran-2-yl)-allylidenamino)-1-R1-4H-1,2,4-triazole halides derivatives

Zaporožskij Medicinskij Žurnal, 2015
Aim. A number of new 3,5-R-4-(3-(5-nitrofuran-2-yl)allylidenami-no)-1-R1-4H-1,2,4-triazole halides have been synthesized, the structure of synthesized compounds has been proved by modern physical-chemical methods. Methods and results.
T. S. Brytanova , A. S. Gotsulya, O. I. Panasenko, Ye. G. Knysh, N. S. Fedyunina   +4 more
doaj   +1 more source

The risk of developing a Clostridium difficile infection from the administration of different classes of antibiotics and their combinations to children in an oncological hospital

Microbiology Independent Research Journal, 2020
Patients in pediatric oncological hospitals are at risk of developing a Clostridium difficile infection. The purpose of this study was to determine the risk of developing a Clostridium difficile infection in patients who are treated with antibiotics ...
Mariya G. Shvydkaya, Aleksandr M. Zatevalov, Dzhamilya T. Dzhandarova, Sergey D. Mitrokhin   +3 more
doaj   +1 more source

Heterocycle‐Tethered Aurones: Synthesis and Evaluation of α‐Glucosidase Inhibition

BioMed Research International, Volume 2026, Issue 1, 2026.
A wide range of heterocycle‐tethered aurones were synthesized using an efficient approach for the capture of in situ generated aurone‐based ortho‐quinone methide intermediates by 3‐(2‐hydroxyphenyl)enaminones and further ring‐opening and ring‐closure reaction with bidentate nucleophiles.
Oleksandr L. Kobzar, Antonina V. Popova, Svitlana P. Bondarenko, Galyna P. Mrug, Andriy I. Vovk, Mykhaylo S. Frasinyuk, Nahit Gencer   +6 more
wiley   +1 more source

Alterations in the cellular DNA and protein content determined by flow cytometry as indicators for chemically induced structural and numerical chromosome aberrations [PDF]

, 2017
Cellular DNA and protein content were determined simultaneously in freshly isolated fibroblast-like rat cells by flow cytometry. After exposure to doxorubicin, nitrofurantoin, propranolol and practolol at a low, tissue like oxygen concentration (5% O2 ...
Maier, Peter, Schawalder, Hanspeter
core  

The Role and Therapeutic Potential of the cGAS‐STING Signaling Pathway in Alzheimer's Disease

Brain and Behavior, Volume 15, Issue 12, December 2025.
This work reveals the relationship between the cGAS‐STING signaling pathway and the pathological mechanisms of Alzheimer's disease.The role of the cGAS‐STING signaling pathway in AD pathology. AD leads to the production of neutrophil extracellular traps (NETs), endoplasmic reticulum (ER) stress, and the release of mitochondrial DNA (mtDNA) and nuclear ...
Xue Li, Wei Gao, Qiuyan Ye, Honglin Li
wiley   +1 more source

Evaluating additives for swine rations (1993) [PDF]

, 1993
Swine producers today are making decisions about feed additives, which are promoted as an aid in reducing feed required per pound of gain. Additives on the market have been selected from a large number investigated for use in treatment of swine diseases ...
Rea, John Cyrus, Veum, Trygve Lauritz, 1940-   +1 more
core