Results 51 to 60 of about 1,949 (178)

Analysis of multiple bacterial species and antibiotic classes reveals large variation in the association between seasonal antibiotic use and resistance.

PLoS Biology, 2022
Understanding how antibiotic use drives resistance is crucial for guiding effective strategies to limit the spread of resistance, but the use-resistance relationship across pathogens and antibiotics remains unclear.
Daphne S Sun, Stephen M Kissler, Sanjat Kanjilal, Scott W Olesen, Marc Lipsitch, Yonatan H Grad   +5 more
doaj   +1 more source

Synthesis and antimicrobial activity of 3,5-R-4-(3-(5-nitrofuran-2-yl)-allylidenamino)-1-R1-4H-1,2,4-triazole halides derivatives

Zaporožskij Medicinskij Žurnal, 2015
Aim. A number of new 3,5-R-4-(3-(5-nitrofuran-2-yl)allylidenami-no)-1-R1-4H-1,2,4-triazole halides have been synthesized, the structure of synthesized compounds has been proved by modern physical-chemical methods. Methods and results.
T. S. Brytanova , A. S. Gotsulya, O. I. Panasenko, Ye. G. Knysh, N. S. Fedyunina   +4 more
doaj   +1 more source

Precision‐Engineered Poly(GMA‐EGDMA) Microspheres for Multifunctional Applications

Particle &Particle Systems Characterization, Volume 43, Issue 1, January 2026.
The study presents multifunctional poly(GMA‐EGDMA) microspheres designed for advanced separation, catalysis, and biomedical engineering. Through precision synthesis and surface engineering, these microspheres exhibit excellent stability, tunable porosity, and high reactivity.
Imran Ali, Shakeel Ahmad Khan, Mujeeb ur Rahman, Abdul Wasy Zia   +3 more
wiley   +1 more source

ANTIMICROBIAL ACTIVITY OF N-ARILIDENHYDRAZIDE OF CARBOXYETHYLALGINIC ACID

Разработка и регистрация лекарственных средств, 2019
The antibacterial and antifungal activity of the products of the interaction of hydrazides of carboxyethyl alginic acid with 5-nitrofurfurol and β-(5-nitro-2-furyl)-acrolein was studied.
D. N. Kosareva, T. I. Taradeyko, S. N. Galasheva, E. P. Ananieva, A. A. Iozep   +4 more
doaj  

The risk of developing a Clostridium difficile infection from the administration of different classes of antibiotics and their combinations to children in an oncological hospital

Microbiology Independent Research Journal, 2020
Patients in pediatric oncological hospitals are at risk of developing a Clostridium difficile infection. The purpose of this study was to determine the risk of developing a Clostridium difficile infection in patients who are treated with antibiotics ...
Mariya G. Shvydkaya, Aleksandr M. Zatevalov, Dzhamilya T. Dzhandarova, Sergey D. Mitrokhin   +3 more
doaj   +1 more source

Synthesis, Antitubercular Activity, and Computational Characterization of Novel Phenylpyrazole‐Isoniazid Derivatives

Advances in Pharmacological and Pharmaceutical Sciences, Volume 2026, Issue 1, 2026.
Six new phenyl‐1H‐pyrazole‐carbaldehyde isonicotinylhydrazone derivatives 1-10 were synthesized and characterized by spectroscopic (FT‐IR, 1H NMR, and 13C NMR) techniques and electrospray ionization–mass spectrometry (ESI–MS). Homonuclear data from 2D‐NMR (1H‐1H NOESY) revealed that 3 and 5 adopt the transE isomeric form.
Fernando Carrasco, Wilfredo Hernández, Juan Z. Dávalos, Jackeline Mosquera, Oscar Chupayo, Nelly Sivipaucar, Jaime Tamayo, Eduardo Carrasco-S, Jorge Coronel, Osvaldo Yañez, William Tiznado, Anjali Chauhan   +11 more
wiley   +1 more source

The Nitrofuran-Warhead-Equipped Spirocyclic Azetidines Show Excellent Activity against Mycobacterium tuberculosis

Molecules
A series of 21 new 7′H-spiro[azetidine-3,5′-furo [3,4-d]pyrimidine]s substituted at the pyrimidine ring second position were synthesized. The compounds showed high antibacterial in vitro activity against M. tuberculosis.
Kristina Komarova, Lyubov Vinogradova, Alexey Lukin, Maxim Zhuravlev, Dmitry Deniskin, Mikhail Chudinov, Maxim Gureev, Marine Dogonadze, Natalia Zabolotnykh, Tatiana Vinogradova, Anastasia Lavrova, Petr Yablonskiy   +11 more
doaj   +1 more source

Isolation of a Protease‐Producing Microbacterium From the Intestinal Tract of Ruditapes philippinarum and Its Probiotic Effects

Aquaculture Nutrition, Volume 2026, Issue 1, 2026.
Aquatic probiotics are generally recognized as safe and nontoxic live bacterial preparations, primarily sourced from the culturing environment or directly from aquatic organisms. Upon entering the aquatic environment, these probiotics are capable of colonizing both the surface and internal compartments of aquatic organisms, thereby enhancing their ...
Hui Guan, Yaodong Qiu, Mingyue Guan, Sitong Quan, Shang Liu, Yingxu Chen, Haochen Li, Haolin Yu, Lei Fang, Zhongming Huo, Arkadios Dimitroglou   +10 more
wiley   +1 more source

Synthesis, Structural Characterization, and DFT Studies of Fe(III), Co(II), and Ni(II) Mixed‐Ligand Complexes With Albendazole and Nifuroxazide With Molecular Docking Against Respiratory Pathogen Targets

Bioinorganic Chemistry and Applications, Volume 2026, Issue 1, 2026.
In this study, the structural, electronic, and biological characteristics of newly synthesized transition metal complexes FeABNF, CoABNF, and NiABNF, resulting from the chelation compounds albendazole (AB) and nifuroxazide (NF), were studied. The synthesized compounds were found to have excellent yields with high percentage yields (∼80%).
Yousef Aldabayan S., Hany M. Abd El-Lateef, Mai M. Khalaf, Aly Abdou, Guillermo Mendoza-Diaz   +4 more
wiley   +1 more source

Heterocycle‐Tethered Aurones: Synthesis and Evaluation of α‐Glucosidase Inhibition

BioMed Research International, Volume 2026, Issue 1, 2026.
A wide range of heterocycle‐tethered aurones were synthesized using an efficient approach for the capture of in situ generated aurone‐based ortho‐quinone methide intermediates by 3‐(2‐hydroxyphenyl)enaminones and further ring‐opening and ring‐closure reaction with bidentate nucleophiles.
Oleksandr L. Kobzar, Antonina V. Popova, Svitlana P. Bondarenko, Galyna P. Mrug, Andriy I. Vovk, Mykhaylo S. Frasinyuk, Nahit Gencer   +6 more
wiley   +1 more source