Results 101 to 110 of about 31,582 (220)

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Adult and Pediatric Intra-Institutional Trends of Ciprofloxacin Susceptibility in E. coli Positive Urinary Cultures

Antibiotics, 2014
Antimicrobial drug resistance in treatment of urinary tract infection (UTI) continues to rise worldwide. To examine contributions of physician prescribing patterns to fluoroquinolone (ciprofloxacin, CP) resistance, we examined Escherichia coli (E.
Winifred Owumi, Niaz Banaei, Linda D. Shortliffe   +2 more
doaj   +1 more source

Application of firefly luciferase assay for adenosine triphosphate (ATP) to antimicrobial drug sensitivity testing [PDF]

The development of a rapid method for determining microbial susceptibilities to antibiotics using the firefly luciferase assay for adenosine triphosphate (ATP) is documented. The reduction of bacterial ATP by an antimicrobial agent was determined to be a
Barza, M. J., Chappelle, E. W., Deming, J. W., Picciolo, G. L., Schrock, C. G., Tuttle, S. A., Wienstein, L.   +6 more
core   +1 more source

Raman and Terahertz Spectroscopic Investigation of Cocrystal Formation Involving Antibiotic Nitrofurantoin Drug and Coformer 4-aminobenzoic Acid

Crystals, 2016
Cocrystallization could improve most physicochemical properties of specific active pharmaceutical ingredients, which has great potential in pharmaceutical development.
Yong Du, Qiang Cai, Jiadan Xue, Qi Zhang
doaj   +1 more source

First lead structure for nitrofurantoin resistance inhibition activity against Enterobacteria

Journal of Medicinal Plants, 2003
We have previously shown that the ethanolic diluted essential oils of the aerial parts of Mentha longifolia could have nitrofurantoin resistance breaker activity against nitrofurantoin resistances Entherobacteriaceae.
AR Shahverdi, F Tavassoli
doaj  

Enhanced Drug Dissolution of Nitrofurantoin Using a Solid Dispersion Technique

BIO Integration
Background: Nitrofurantoin is a BCS II drug with a low solubility and dissolution rate. Therefore, the pharmaceutical applications of nitrofurantoin are limited.
D. S. Bhosale, M. S. Kalshetti
doaj   +1 more source

Microbial Load Monitor [PDF]

The Microbial Load Monitor (MLM) is an automated and computerized system for detection and identification of microorganisms. Additionally, the system is designed to enumerate and provide antimicrobic susceptibility profiles for medically significant ...
Gibson, S. F., Royer, E. R.
core   +1 more source

Management of urinary tract infections in elderly at the Rehabilitation Hospital Karin Grech [PDF]

, 2014
OBJECTIVE: To assess the percentage of patients suffering from urinary tract infections (UTIs) who were treated at the Rehabilitation Hospital Karin Grech (RHKG) and to evaluate treatment choices used to manage UTIs at the same hospital during a one ...
Ali Omar, Asma, Azzopardi, Lilian M.
core  

The Anterior Tarsal Tunnel Syndrome [PDF]

, 1977
Krause, Klaus-Henning, Ross, A., Witt, T. N.   +2 more
core   +1 more source

Evaluation 1- year period pathogens and antibiograms in urine Culturs in Ardabil Laboratories [PDF]

Introduction: Urinary tract infection Spans all age groups and considered as a serious and common bacterial infection in children it maybe a symptomatic or an asymptomatic type.
شاددل, لیلا, صالح زاده, فرهاد, علیمحمدی, حسین   +2 more
core