Results 81 to 90 of about 23,620 (204)

Women's Experiences of Recurrent UTIs: A Qualitative Study of Preventive Management and Decision Support Needs

Health Expectations, Volume 29, Issue 5, October 2026.
ABSTRACT Introduction Recurrent urinary tract infections (rUTIs) are common in women and significantly impact their daily lives. Prophylactic antibiotics are the primary preventive option for rUTIs when other options have been unsuccessful, but their use can increase the risk of antimicrobial resistance.
Catherine V. Hayes, Donna M. Lecky, Haroon Ahmed, Rebecca Cannings‐John, Adrian Edwards, Fiona Wood, Leigh Sanyaolu   +6 more
wiley   +1 more source

Nitrofurantoin methanol monosolvate

, 2011
The antibiotic nitrofurantoin {systematic name: (E)-1-[(5-nitro-2-furyl)methylideneamino]imidazolidine-2,4-dione} crystallizes as a methanol monosolvate, C8H6N4O5·CH4O.
Chow, P.S., Pui Shan Chow, Vangala, V.R., Venu R. Vangala, Tan, R.B.H., Reginald B. H. Tan   +5 more
core   +1 more source

Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang, Changbin Zhang, Mengyuan Lyu, Yongbo Luo, Jierou Zhang, Yujiao Chen, Lintao Luo, Wen Qiao, Xiangyangpeng Li, Yu Zhou, Zhongling Wei, Yuling Xiao, Qian Niu, Juan Zhou, Guanglin He, Binwu Ying, Zhaoming Su, Hao Chen, Xiaodi Tang, Haohao Dong   +19 more
wiley   +1 more source

Nitrofurantoin-induced lung- and hepatotoxicity

, 2017
We present the case of a patient referred to the gastroenterology service for investigation of abnormal liver function tests. She had been taking nitrofurantoin for 16 months as prophylaxis against urinary tract infections.
Tan, Chew, Moschos, John, Bhat, Shivaram, Koulaouzidis, Anastasios, De Ramón, Ana   +4 more
core  

Microsomal oxidative stress induced by NADPH is inhibited by nitrofurantoin redox biotranformation [PDF]

, 2014
Nitrofurantoin is used in the antibacterial therapy of the urinary tract. This therapy is associated with various adverse eff ects whose mechanisms remain unclear.
Lazo Hernández, Carlos Enrique, Molina Berríos, Alfredo Enrique, Larraín, J. I., Navarro, J., Aracena, P., Letelier, M. E., Reinoso, C., Sepúlveda, D. R.   +7 more
core   +1 more source

Reduced Graphene Oxide/β-Cyclodextrin Nanocomposite for the Electrochemical Detection of Nitrofurantoin

Chemosensors
In this work, a glassy carbon electrode (GCE) modified with reduced graphene oxide and β-cyclodextrin (rGO/β-CD) nanocomposite was developed for the electrochemical detection of nitrofurantoin (NFT).
Al Amin, Gajapaneni Venkata Prasad, Venkatachalam Vinothkumar, Seung Joo Jang, Da Eun Oh, Tae Hyun Kim   +5 more
doaj   +1 more source

Identification of a Nonribosomal Peptide Analog With Activity Against Multiple Gram‐Positive Bacteria via a Synthetic Bioinformatic Natural Product Discovery Approach

Advanced Science, Volume 13, Issue 50, 7 September 2026.
The genome of Rhodococcus erythropolis D‐1 was analyzed by bioinformatic tools to mine a novel nonribosomal peptide synthetase (NRPS) gene cluster. A nonribosomal peptide analog ZURJC5 associated with the NRPS was chemically synthesized. Through structure‐activity relationship studies, ZURJC28 was ultimately obtained and showed antibacterial activity ...
Keyi Chen, Jiayi Liang, Yujia Wu, Jianan Xu, Yi Liu, Wenguang Wang, Xinhang Jiang, Benjie Gao, Yueyue Wang, Hui Jiang   +9 more
wiley   +1 more source

Rapid in vitro and in vivo conversion of hydroxymethyl-nitrofurantoin into nitrofurantoin as measured by HPLC

, 1979
For the first time a method of separation between nitrofurantion and hydroxymethylnitrofurantoin is reported. Until now it has not been possible to separate these two substances because of a rapid degradation of hydroxymethyl-nitrofurantoin into ...
Sorel, R.H.A., Roseboom, H.
core  

Acute Respiratory Distress Syndrome and Hepatotoxicity Associated with Single Dose Nitrofurantoin Use [PDF]

, 2012
Nitrofurantoin is a synthetic nitrofuran compound. It is generally used in urinary tract infections, either alone or in combination with other antibiotics. A number of adverse effects may develop in different body systems during nitrofurantoin treatment;
Gokhan Sargın, Osman Elbek, Cem Balantekin, İbrahim Meteoglu, Nil Culhacı   +4 more
core   +1 more source

Mycobacterium tuberculosis acg Gene Is Required for Growth and Virulence In Vivo. [PDF]

, 2011
Mycobacterium tuberculosis dosRS two-component regulatory system controls transcription of approximately 50 genes including hspX, acg and Rv2030c, in response to hypoxia and nitric oxide conditions and within macrophages and mice.
Hu, Y, Yanmin Hu, Hu Yanmin, Anthony R M Coates, Anthony R. M. Coates, Coates, AR, Coates Anthony R. M.   +6 more
core   +2 more sources