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Clinical Pharmacology and Therapeutics, 1981
Nitrofurantoin (50 mg) was administered in a three-way random crossover design to six healthy men. After a 45-min intravenous infusion the plasma concentration data could be described by a two-compartment open-body model with a terminal t 1/2 of 58.1 +/- 15 min. Oral availability of a tablet was 0.87 +/- 0.13 on a fasting stomach and 0.94 +/- 0.13 when
B, Hoener, S E, Patterson
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Nitrofurantoin (50 mg) was administered in a three-way random crossover design to six healthy men. After a 45-min intravenous infusion the plasma concentration data could be described by a two-compartment open-body model with a terminal t 1/2 of 58.1 +/- 15 min. Oral availability of a tablet was 0.87 +/- 0.13 on a fasting stomach and 0.94 +/- 0.13 when
B, Hoener, S E, Patterson
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Drug Intelligence & Clinical Pharmacy, 1985
For more than 30 years nitrofurantoin has been a widely prescribed and effective agent in the treatment of urinary tract infections. During this time, it has withstood the rigors of constant clinical evaluation and has competed successfully with more recent antibacterial agents.
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For more than 30 years nitrofurantoin has been a widely prescribed and effective agent in the treatment of urinary tract infections. During this time, it has withstood the rigors of constant clinical evaluation and has competed successfully with more recent antibacterial agents.
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Obstetrical & Gynecological Survey, 1989
Nitrofurantoin has been in clinical use for more than 35 years for the treatment of urinary tract infections (UTIs). In particular, it has been used to treat acute uncomplicated UTIs, recurrent urinary tract infections, and asymptomatic bacteriuria of pregnancy. Most recently, it has been used for both prophylaxis and treatment of nosocomial infections
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Nitrofurantoin has been in clinical use for more than 35 years for the treatment of urinary tract infections (UTIs). In particular, it has been used to treat acute uncomplicated UTIs, recurrent urinary tract infections, and asymptomatic bacteriuria of pregnancy. Most recently, it has been used for both prophylaxis and treatment of nosocomial infections
openaire +2 more sources