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Spectrophotometric Determination of Nitrofurazone
Analytical Letters, 1986Abstract A new sensitive and seleactive method for rapid and accurated determination of nitrofarazone is described. The nitrofurazone is reacted with hydroxyl-amine hydrochloride in alkaline medium to give hydroxamic acid which forms the purple violet coloured complex with iron (III), FeCl3, in acidic medium.
Y. K. Agrawal, D. R. Patel
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DERMATITIS FOLLOWING THE USE OF NITROFURAZONE
Archives of Dermatology, 1948A new group of bacteriostatic agents, the nitrofurans, of which 5-nitro-2-furaldehyde semicarbazone 1 is an example, has been found effective in the treatment of infected wounds. 2 To our knowledge, no examples of cutaneous sensitization to this particular group of drugs have been reported.
W R, HILL, W E, FLOOD
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Site of Reduction of Nitrofurazone by Bacteria
Nature, 1957ANTIBACTERIAL, nitrofurans are reduced to the corresponding amino-compounds by Aerobacter aerogenes 1. The site of the reaction (in a different organism) is now shown to be the cytoplasmic membrane rather than the cell wall or cytoplasm. Lack of an enzyme system capable of effecting this reaction in the bacterial cell walls was not unexpected2.
A H, BECKETT, A E, ROBINSON
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