Results 81 to 90 of about 4,154 (206)

Dyclonine rescues frataxin deficiency in animal models and buccal cells of patients with Friedreich's ataxia. [PDF]

, 2014
Inherited deficiency in the mitochondrial protein frataxin (FXN) causes the rare disease Friedreich's ataxia (FA), for which there is no successful treatment. We identified a redox deficiency in FA cells and used this to model the disease.
Al-Mahdawi, Al-Mahdawi, Al-Mahdawi, Albano, Bidichandani, Brandon Brown, Brian D. Scott, Bridwell-Rabb, Campuzano, Catterall, Chantrel-Groussard, Chorley, Chutake, Condò, Cossée, Cox, De Biase, Deutsch, Drechsel, Dürr, Fahey, Filla, Florestano, Frank, Friedman, Gino A. Cortopassi, Greene, Hashemy, Heike Wulff, Huang, Kalinin, Kensler, Kim, Kim, Koeppen, Koeppen, Kosower, Kosower, Kruger, Lai, Larkin, Liu, Lopert, Lu, Lu, Marissa Z. McMackin, Mark A. Pook, Miranda, Mittal Jasoliya, Montermini, Osburn, Paredes-Gonzalez, Paupe, Riah, Sandi, Sangster, Saveliev, Schmitz-Hübsch, Selak, Shan, Shan, Shan, Shelmire, Sinha, Streck, Subramaniam, Sunil Sahdeo, Susan L. Perlman, Tan, Tan, Tella, Verdon, Wang, Wang, Weaver, Willis, Yang, Yu, Zhang   +78 more
core   +1 more source

Isoniazid‐Dihydropyrimidinone Molecular Hybrids: Design, Synthesis, Antitubercular Activity, and Cytotoxicity Investigations with Computational Validation

ChemMedChem, Volume 20, Issue 11, June 2, 2025.
Antitubercular evaluation of a novel library of isoniazid‐dihydropyrimidinone molecular hybrids (8a–8n) discloses a potent compound with MIC = 0.39μg mL−1 against M. tuberculosis mc26230. Cytotoxicity, stability, and in silico studies, including molecular docking and ADME/T (absorption, distribution, metabolism, excretion, and toxicity) analysis ...
Gobind Kumar, Pule Seboletswe, Sahil Mishra, Neha Manhas, Safiyah Ghumran, Nagaraju Kerru, Françoise Roquet‐Banères, Maëlle Foubert, Laurent Kremer, Gaurav Bhargava, Parvesh Singh   +10 more
wiley   +1 more source

Electrochemical Behavior of Nitrofurazone in Aqueous Media Applying Multi‐Walled Carbon Nanotubes and Cu‐Phthalocyanine

Electroanalysis, Volume 37, Issue 6, June 2025.
Under alkaline conditions (pH > 9), hydroxyl ions promote the formation of Cu(OH)2 on the CuPc surface, which is electrochemically oxidized to generate Cu(III) (CuOOH). This high‐valent copper species acts as an electron‐transfer mediator, facilitating the one‐electron reduction of nitrofurazone to its nitro‐anion radical (R‐NO2•−) and subsequently ...
Charles L. Brito, Elizabeth I. Ferreira, Mauro A. La‐Scalea   +2 more
wiley   +1 more source

Probiotic Characteristics of Bifidobacterium Spp. by in Vitro Assessment [PDF]

, 1996
Probiotics are organisms which are natural gut isolates and used as dietary adjuncts that is believed to benefit man and animals. An organism to be selected as a probiotic should posses certain important characteristics.
Vengrasalam, Kalaivaani
core  

Safe and effective catheterisation for patients in the community [PDF]

, 2015
Approximately 450 000 people use long-term urinary catheters in the UK. Permanent catheters are used by 3% of the community population and occupy an estimated 4% of a district nurse's caseload in the UK.
Bardsley, Alison
core   +1 more source

Histopathologic study of the effect of low level Gallium-Arsenide laser on healing of grade 3 cutaneous burns in the rat [PDF]

Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2017
The healing of burn wounds has always attracted attention due to disruption of the healing process which leads to prolonged recovery period. Therefore, the quest for finding clinically effective wound-healing agents is important in the medical management
siamand bastani, a rezaei
doaj  

Evaluation of contact sensitivity to topical drugs in patients with contact dermatitis [PDF]

, 2013
Background and Design: Topical drugs are an important group of contact allergens. The present study aimed to evaluate contact sensitivity to topical drugs in patients with contact dermatitis.
Aynur Akyol, Ayşe Boyvat, Bilge Bülbül Şen   +2 more
core  

Effects of two common antibiotics on the skin microbiome of ornamental reef fishes: Implications for manipulative experiments in microbial dynamics

Aquaculture, Fish and Fisheries
An understanding of the mechanistic drivers of animal‐microbial symbiosis and associations generally requires experiments that manipulate specific symbionts or microbial communities.
Ana Pereira, Anya Brown, Davis Strobel, Marta C. Soares, Raquel Xavier, Amy Apprill, Paul Sikkel   +6 more
doaj   +1 more source

Chromatographic detection of nitrofurans in foods of animal origin

Arquivos do Instituto Biológico
Nitrofurans are antibacterials banned in livestock by different countries due to its relationship with the production of carcinogenic metabolites. Several studies have been conducted to find the best methodology to identify these residues.
César Aquiles Lázaro de la Torre, Juan Espinoza Blanco, Joab Trajano Silva, Vânia Margaret Flosi Paschoalin, Carlos Adam Conte Júnior   +4 more
doaj   +1 more source

Effect of cow urine on wound healing property in Wister Albino Rats [PDF]

Veterinary World, 2011
The wound healing activity of cow urine was studied in Wistar albino rats. The efficacy of wound healing property was evaluated by excision wound model. The parameter studied was the rate of wound contraction.
V.P. Tikare.,Paniraj K.L and Swetha R, Jayakumar.K., Jayaramu G.M., Jagadeesh S. Sanganal   +3 more
doaj