Results 181 to 190 of about 27,351 (240)

Evaluation of a pantoprazole and 4‐desmethylpantoprazole‐sulfate metabolic ratio as a novel CYP2C19 phenotyping method

British Journal of Clinical Pharmacology, EarlyView.
Aims CYP2C19 is one of the most important pharmacogenes, and its activity is highly variable due to factors such as genetics or drug–drug interactions. Due to the lack of an appropriate endogenous CYP2C19 biomarker, surrogate methods to assess its activity are warranted.
Julian Peter Müller, Vladimir N. Belov, Sabrina Yamoune, Bob Miller, Mohammed Hasoumi, Jolanta Tupiec, Thea Laurentius, L. Cornelius Bollheimer, Julia C. Stingl, Katja S. Just   +9 more
wiley   +1 more source

Dietary inequality marker reveals 10,000 years of gender and cultural disparity in Europe. [PDF]

PNAS Nexus
Colleter R, Jaouen K, Garcia D, Richards MP.   +3 more
europepmc   +1 more source

Metabolic Flux Analysis Reveals Cell Line‐Specific Rewiring in CHO Cells Following TCA Cycle Intermediate Feeding for Bioprocess pH Control

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Chinese hamster ovary (CHO) cells are the leading host for recombinant therapeutic protein production in the biopharma industry. In this study, we investigated how feeding acidic forms of tricarboxylic acid (TCA) cycle intermediates—malic acid, succinic acid, and α‐ketoglutaric acid—affects cell culture performance and metabolism in two ...
Sarah A. Sacco, Kevin J. Ruiz‐Márquez, Rachel Moen, Irina Trenary, Xiaolin Zhang, Xiaowen Wang, Malik Padellan, Henry Lin, Jamey D. Young   +8 more
wiley   +1 more source

Analyses of eye lens stable isotopes across ontogeny of trophically diverse freshwater salmonids. [PDF]

PLoS One
Schumacher GT, Peebles EB, Furey NB, Kinnison MT, Kronisch GR, Murphy CA.   +5 more
europepmc   +1 more source

Nitrogen Isotope Separation by Laser

Oyo Buturi, 1975
IZAWA, Yasukazu, NOGUCHI, Hirohisa, YAMANAKA, Chiyoe   +2 more
openaire   +1 more source

Challenges and Future Directives of Synthetic Biology in Engineering Plant–Microbe Partnerships for Sustainable Agriculture

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Synthetic biology has recently proven to be a valuable tool for enhancing agriculture even in the face of environmental and biological stresses. Understanding the challenges that militate synthetic biology will assist in ensuring safe, stable, and scalable crop production.
Ben Jesuorsemwen Enagbonma, Rebaona Reaobaka Molefe‐Madlaliso, Alaba Adewole Adebayo, Oghoye Priscilla Oyedoh, Godfrey Okainemen Oribhabor, Oluwaseun Emmanuel Shittu, Olubukola Oluranti Babalola   +6 more
wiley   +1 more source

When collagen fails: Zinc isotopes unlock Sumerian lifeways in southern Mesopotamia. [PDF]

Proc Natl Acad Sci U S A
Giaccari M, Romano L, Soncin S, Panella S, Alhaique F, D'Agostino F, Jaouen K, Tafuri MA.   +7 more
europepmc   +1 more source

Regional variations in the diet of the South Polar Skua (Stercorarius maccormicki) in the Ross Sea region, Antarctica. [PDF]

PLoS One
Kim J, Kim Y, Kim JU, Oh Y, Kim JH.
europepmc   +1 more source

Challenges and Methodologies to Assess Protein Requirement and Quality Across Different Life Stages in Dogs: A Review. [PDF]

Animals (Basel)
Scarpim LB, Pacheco LG.
europepmc   +1 more source

Rising competition among North Sea mammalian top predators: a multi-method perspective on trophic ecology. [PDF]

Sci Rep
Heße E, Boyi JO, Das K, Lehnert K, Piette M, Pinzone M, Siebert U, Gilles A.   +7 more
europepmc   +1 more source