Results 31 to 40 of about 154 (130)

2-Benzyloxy-3-nitropyridine

Acta Crystallographica Section E Structure Reports Online, 2005
The mol­ecule of the title compound, C12H10N2O3, is non-planar. The nitro group is twisted out of the pyridine ring plane by 31.0 (1)°. Inversion-related mol­ecules are arranged in layers.
Yu Cui, Hui-Min Liu, Wen-Qin Zhang
openaire   +1 more source

Intracellular Delivery of Native Proteins by BioReversible Arginine Modification (BioRAM) on Amino Groups

Angewandte Chemie International Edition, Volume 64, Issue 34, August 18, 2025.
Bioreversible Arginine Modification of amine‐containing protein residues (termed BioRAM) allows the serum‐compatible, readily accessible, and efficient delivery of native proteins into live cells. Combined with cell‐penetrating peptide (CPP) additives, BioRAM results in intracellular RNase A activity at nanomolar concentrations, thus enabling the ...
Jonathan Franke, Jan Vincent V. Arafiles, Christian Leis, Christian P. R. Hackenberger   +3 more
wiley   +1 more source

Design, Synthesis, and Molecular Evaluation of SNAr‐Reactive N‐(6‐Fluoro‐3‐Nitropyridin‐2‐yl)Isoquinolin‐3‐Amines as Covalent USP7 Inhibitors Reveals an Unconventional Binding Mode

Archiv der Pharmazie, Volume 358, Issue 8, August 2025.
The ubiquitin‐specific protease 7 (USP7) catalyzes the removal of ubiquitin and protects substrate proteins from degradation. USP7 causes structural changes upon ubiquitin binding, making it particularly suitable for use in covalent targeting approaches. The development, synthesis, and biophysical screening of a series of mildly electrophilic compounds
Larissa N. Ernst, Jason Stahlecker, Finn Mier, Ricardo A. M. Serafim, Valentin R. Wydra, Benedikt Masberg, Simon J. Jaag, Cornelius Knappe, Michael Lämmerhofer, Thilo Stehle, Matthias Gehringer, Frank M. Boeckler   +11 more
wiley   +1 more source

Straightforward and Efficient Protocol for the Synthesis of Pyrazolo [4,3-b]pyridines and Indazoles. [PDF]

Int J Mol Sci, 2023
Nikol'skiy VV, Minyaev ME, Bastrakov MA, Starosotnikov AM.   +3 more
europepmc   +1 more source

P^III/P^V═O-Catalyzed Intermolecular N-N Bond Formation: Cross-Selective Reductive Coupling of Nitroarenes and Anilines. [PDF]

J Am Chem Soc, 2021
Li G, Miller SP, Radosevich AT.
europepmc   +1 more source

Cu-Catalyzed Cross-Coupling of Nitroarenes with Aryl Boronic Acids to Construct Diarylamines. [PDF]

ACS Catal, 2021
Guan X, Zhu H, Driver TG.
europepmc   +1 more source

Synthetic Applications of Nitropyridine Derivatives

, 2010
The present work represents a continuation of the investigation of the chemistry of nitropyridine derivatives, based on the methodology for nitration of pyridines developed by Professor Jan M. Bakke and co-workers at NTNU. Nitropyridines have been utilized as substrates for the formation of novel bis- and tris-heterocyclic compounds, and new synthetic ...
openaire   +2 more sources

Enantioselective inhibition of the SARS-CoV-2 main protease with rhenium(i) picolinic acid complexes. [PDF]

Chem Sci, 2023
Karges J, Giardini MA, Blacque O, Woodworth B, Siqueira-Neto JL, Cohen SM.   +5 more
europepmc   +1 more source

Azides in the Synthesis of Various Heterocycles. [PDF]

Molecules, 2022
Nayl AA, Aly AA, Arafa WAA, Ahmed IM, Abd-Elhamid AI, El-Fakharany EM, Abdelgawad MA, Tawfeek HN, Bräse S.   +8 more
europepmc   +1 more source

The Synthesis of beta-Nitropyridine Compounds. [PDF]

Acta Chemica Scandinavica, 1999
Jan M. Bakke, Eli Ranes, Jaroslav Riha, Harald Svensen, G. Liptay, Jorma Mattinen, Alexander Senning, Xin-Kan Yao, Hong-Gen Wang, J. -P. Tuchagues, Mattias Ögren   +10 more
openaire   +1 more source